Is the rationale more important than deception? A randomized controlled trial of open-label placebo analgesia. Locher C, Frey Nascimento A, Kirsch I, Kossowsky J, Meyer A, Gaab J. Pain. 2017 Dec;158(12):2320 2328. Healthy volunteers were recruited to an experimental heat pain analgesia randomized controlled trial. Forty healthy volunteers in each group were randomly assigned to […]
Category: Short Cuts
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Risk of acute myocardial infarction with NSAIDs in real world use: bayesian meta-analysis of individual patient data. Bally M, Dendukuri N, Rich B, Nadeau L, Helin-Salmivaara A, Garbe E, Brophy JM. BMJ. 2017 May 9;357:j1909. A bayesian meta-analysis of individual patient data from Canadian and European healthcare databases (61460 cases of acute myocardial infarction and […]
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C-reactive protein, symptoms and activity of daily living in patients with advanced cancer receiving palliative care. Amano K, Maeda I, Morita T, et al J Cachexia Sarcopenia Muscle. 2017 Jun;8(3):457-465. A secondary data analysis of a cross-sectional study looked at the associations between C-reactive protein (CRP) level, manual muscle testing of limbs, symptoms and activities […]
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Retrospective review of serotonergic medication tolerability in patients with neuroendocrine tumors with biochemically proven carcinoid syndrome. Shi DD, Yuppa DP, Dutton T, et al. Cancer. 2017 Jul 15;123(14):2735-2742 A retrospective review of patients with metastatic carcinoid tumours and elevated serotonin levels who received serotonergic antidepressants was performed to evaluate the effect of serotonergic antidepressants on […]
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Prevalence and incidence of chronic pain with or without neuropathic characteristics in patients with cancer. Bouhassira D, Luporsi E, Krakowski I. Pain. 2017 Jun;158(6):1118-1125. A prospective observational study in France recruited 1805 cancer patients attending out-patients for cancer treatment from 12 oncology units. A clinical examination, DN4 questionnaire and Brief Pain Inventory were used to […]
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Cost analysis of a prospective multi-site cohort study of palliative care consultation teams for adults with advanced cancer: Where do cost-savings come from? May P, Garrido MM, Cassel JB, Kelley AS, Meier DE, Normand C, Smith TJ, Morrison RS. Palliat Med. 2017 Apr;31(4):378-386. A prospective multi-site cohort study in three US hospitals included 863 […]
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Comparing the symptom experience of cancer patients and non-cancer patients. Deshields TL, Penalba V, Liu J, Avery J. Support Care Cancer. 2017 Apr;25(4):1103-1109. This study focussed on symptom burden of 301 consecutive patients from a general medical clinic and 558 cancer patients from a tumour registry who completed the Memorial Symptom Assessment Scale. Results […]
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Predictors of Complicated Grief and Depression in Bereaved Caregivers: A Nationwide Prospective Cohort Study. Nielsen MK, Neergaard MA, Jensen AB, et al. J Pain Symptom Manage. 2017 Mar;53(3):540-550 A prospective survey of 3635 caregivers to terminally ill patients in Denmark was conducted. 2420 were bereaved within six months and of the survey, 2125 (88%) […]
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A systematic review of prognostic factors at the end of life for people with a hematological malignancy. Button E, Chan RJ, Chambers S, Butler J, Yates P. BMC Cancer. 2017 Mar 23;17(1):213. This systematic review looked at identifying prognostic factors in the last 3 months of life that are associated with increased risk of […]
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Caregivers’ Perspectives on the Use of Long-Term Oxygen Therapy for the Treatment of Refractory Breathlessness: A Qualitative Study Aileen Collier, Katrina Breaden, Jane L. Phillips, Meera Agar, Caroline Litster, David C. Currow. J Pain Symptom Manage. 2017 Jan;53(1):33-39. A qualitative study of the perspectives of 20 caregivers in the palliative setting of patients on […]