The issue of whether excessive work may lead to increased weakness in hereditary neuropathy is a vexing one and critical for patient management. in this issue of JNNP this notion has been categorcially dismissed. There was no worsening weakness with overwork in a large CMT1A cohort.
Read more: http://jnnp.bmj.com/content/85/12/1354.abstract
Neurol Neurosurg Psychiatry 2014;85:1354-1358 doi:10.1136/jnnp-2014-307598
- Neuromuscular
- Research paper
Is overwork weakness relevant in Charcot–Marie–Tooth disease?
- G Piscosquito1,
- M M Reilly2,
- A Schenone3,
- G M Fabrizi4,
- T Cavallaro4,
- L Santoro5,
- G Vita6,
- A Quattrone7,
- L Padua8,
- F Gemignani9,
- F Visioli10,11,
- M Laurà2,
- D Calabrese1,
- R A C Hughes2,
- D Radice12,
- A Solari1,
- D Pareyson1
- for the CMT-TRIAAL & CMT-TRAUK Group
+ Author Affiliations
(Visited 158 times, 1 visits today)