Progression in MS has been associated with cortical atrophy. Consequently, the holy grail of trying to prevent diability development in MS is to slow or even prevent the rate of cortical atrophy. In this issue of JNNP, Zivadinovs groups elegantly demonstrate that cortical atrophy evolves over a 10 year period, being more pronounced in those patients developing disability. This is an important study, especially when drug therapies are considered.
Read more at: http://jnnp.bmj.com/content/85/10/1109.abstract
- Multiple sclerosis
- Research paper
Brain atrophy and disability progression in multiple sclerosis patients: a 10-year follow-up study