Guillain-Barre syndrome (GBS) is an autoimmune neuropathy with a heterogeneous etiology affecting both the myelin and the axon.  GBS is probably the most frequent cause of a rapidly progressive neuropathy in the Western world.  Although the demyelinating variant is more frequent in Western forms of GBS in Asia, the axonal form (termed AMAN) is more frequent.  The review by Bae and colleagues in this issue of JNNP is an authoritative review on the topic providing novel clinical, physiological, pathological and pathophysiological insights.

Must read at http://jnnp.bmj.com/content/85/8/907.abstract

Guillain–Barré syndrome in Asia