Top 10 most read in June 2024 – a focus on Study Protocols

In June, there were 7 new entries to our top 10 list, 5 of which were protocol articles. Protocols are vital for open science, preventing unnecessary duplication of work and increasing transparency beyond what traditional registries can provide. As highlighted by their prevalence in this months most-read articles, they also are great for providing exposure to new research activity, ultimately allowing researchers and funding bodies to keep up-to-date with their fields and to hopefully foster collaboration in the research community. Please see the table for the full details of this months articles, though 2 protocols are highlighted below.

In a new addition to the top ten, the most read article of the month comes from Wijma et al who present a single-centre, single-arm, non-randomised clinical trial which aims to investigate the effect of a home-based bimodal lifestyle programme (“FIT4Cirrhotics@Home”) in patients with end stage liver disease awaiting transplantation. The intervention is an exercise programme combined with nutritional support, and the authors aim to complete recruitment in early 2025. See the link for more details of the study.

Another new addition is the protocol presented by Xiao et al where the authors plan to assess the associations between online and in-person social interaction, and measures of mental health (loneliness) in adolescents in Scotland. Adolescents increasingly interact digitally, though whether online and offline social interaction have distinct effects on the levels of loneliness and mental health isn’t clear. The authors plan to conduct a patient and public involvement phase to help inform the full design of the final Ecological Momentary Assessment (EMA) study.

 

Kip et al, Bjornsdottir et al, and van Dijk et al, all keep a spot in the top 10 – please see previous blogs for a summary of van Dijk et al, who present a perspective article discussing the use of artificial intelligence in systematic reviews and meta-analysis.

Below are the top ten most-read papers in BMJ Open during June 2024:

*Most read figures are based on pdf downloads and full text views. Abstract views are excluded.
Rank* Author(s) Title
1 Wijma et al. Effects of a home-based bimodal lifestyle intervention in frail patients with end-stage liver disease awaiting orthotopic liver transplantation: study protocol of a non-randomised clinical trial
2 Kip et al. Is LDL cholesterol associated with long-term mortality among primary prevention adults? A retrospective cohort study from a large healthcare system
3 Naik et al. Low-dose naltrexone for post-COVID fatigue syndrome: a study protocol for a double-blind, randomised trial in British Columbia
4 Bjornsdottir et al. Association between physical activity over a 10-year period and current insomnia symptoms, sleep duration and daytime sleepiness: a European population-based study
5 Calvet et al. Viral shedding of SARS-CoV-2 in body fluids associated with sexual activity: a systematic review and meta-analysis
6 van Dijk et al. Artificial intelligence in systematic reviews: promising when appropriately used
7 Zemouri et al. Exploring discrimination and racism in healthcare: a qualitative phenomenology study of Dutch persons with migration backgrounds
8 Xiao et al. Loneliness in the Digital World: protocol for a co-produced ecological momentary assessment study in adolescents
9 Graham et al. Realist process evaluation of occupational performance coaching: protocol
10 Besnier et al. Opioid-free anaesthesia with dexmedetomidine and lidocaine versus remifentanil-based anaesthesia in cardiac surgery: study protocol of a French randomised, multicentre and single-blinded OFACS trial

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