Expanding the antibody spectrum of limbic encephalitis!

Limbic encephalitis (LE) mat have an underlying autoimmune etiologiy.  over the last decade numerous antibodies have emerged as potenital causative agents, and the antibodies have been directed against external epitopes of specific receptors.  In an upcoming issue of JNNP, Onugoren and colleagues reaffirm the association between GABAB and AMPR receptor antibodies and LE.  Importantly neoplastic causes need to be considered.

 

Read more at :  http://jnnp.bmj.com/content/early/2014/10/09/jnnp-2014-308814.full

 

Typical MRI changes in LE

Figure 2