Pregnancy and MS. The need to commence treatment post-partum?

Posted on by Steve Vucic, Web Editor

While pregnancy is associated with a reduced risk of relapses, caution is required in the post-partum period.  In this issue of JNNP, Portaccio and colleagues elegantly demonstrate an increased risk of relapse in the post-partum period.   Greater disease activity before and during pregnancy were reported as predictors of an increased chance of a relapse in the post-partum period.  Therapy with DMDs in the immediate post-partum period seemed to reduced risk of future relapse.

 

Read more at http://jnnp.bmj.com/content/85/8/845.abstract

 

Neurol Neurosurg Psychiatry 2014;85:845-850 doi:10.1136/jnnp-2013-306054
  • Multiple sclerosis
  • Research paper

Postpartum relapses increase the risk of disability progression in multiple sclerosis: the role of disease modifying drugs

  1. Emilio Portaccio1,
  2. Angelo Ghezzi2,
  3. Bahia Hakiki1,
  4. Andrea Sturchio1,
  5. Vittorio Martinelli3,
  6. Lucia Moiola3,
  7. Francesco Patti4,
  8. Gian Luigi Mancardi5,
  9. Claudio Solaro6,
  10. Maria Rosaria Tola7,
  11. Carlo Pozzilli8,
  12. Laura De Giglio8,
  13. Rocco Totaro9,
  14. Alessandra Lugaresi10,
  15. Giovanna De Luca10,
  16. Damiano Paolicelli11,
  17. Maria Giovanna Marrosu12,
  18. Giancarlo Comi3,
  19. Maria Trojano11,
  20. Maria Pia Amato1,
  21. for the MS Study Group of the Italian Neurological Society

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