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Archive for February, 2013

All tied up in knots

28 Feb, 13 | by Emma

Anything that is linear and remotely flexible may get knotted up. This is well demonstrated in the images accompanying the present case. Murphy’s law applies, and the advice given by the authors is very sound.

Kirsten Moller

All tied up in knots

Adenocarcinoma: not all that wheezes is asthma

6 Feb, 13 | by Emma

This is well written case report of a rare presentation of a rare condition. It provides a important reminder to consider a differential diagnosis in patients with asthma.

Large airway tumours are rare (0.2%) amongst patients with lung cancer, and amongst tracheal tumours it is thought that adenocarcinomas represent 4-10%.1-5 The majority of tracheal adenocaricinomas are diagnosed in smokers.3-4 In one case series of tracheal tumours 21% had symptoms of progressive bronchial asthma.5

Dr Ian Clifton
St James’s University


1. Li W, Ellerbroek NA, Libshitz HI. Primary malignant tumors of the trachea. A radiologic and clinical study. Cancer 1990;66:894–9.
2. Hajdu SI, Huvos AG, Goodner JT, et al. Carcinoma of the trachea. Clinicopathologic study of 41 cases. Cancer 1970;25:1448–56.
3. Gelder CM, Hetzel MR. Primary tracheal tumours: a national survey. Thorax 1993;48:688–92.
4. Licht PB, Friis S, Pettersson G. Tracheal cancer in Denmark: a nationwide study. Eur J Cardiothorac Surg 2001;19:339–45.
5. Houston HE, Payne WS, Harrison EG Jr, et al. Primary cancers of the trachea. Arch Surg 1969;99:132–40.

Adenocarcinoma: not all that wheezes is asthma

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