{"id":240,"date":"2011-03-02T21:55:12","date_gmt":"2011-03-02T21:55:12","guid":{"rendered":"https:\/\/blogs.bmj.com\/sti\/?p=240"},"modified":"2011-05-02T21:11:01","modified_gmt":"2011-05-02T21:11:01","slug":"so-the-%e2%80%9cclap%e2%80%9d-has-a-human-side","status":"publish","type":"post","link":"https:\/\/blogs.bmj.com\/sti\/2011\/03\/02\/so-the-%e2%80%9cclap%e2%80%9d-has-a-human-side\/","title":{"rendered":"So the \u201cclap\u201d has a human side!"},"content":{"rendered":"

Neisseria gonorrhoeae<\/em> is a nimble bacterium, and past master at adapting itself to resist the challenge of our antibiotics.\u00a0 So maybe we shouldn\u2019t be surprised at this latest accolade: to have been the first proven case of horizontal gene transfer (HGT) between organisms as disparate as the bacterium and a human being!\u00a0 A recent study claims to demonstrate that Neisseria gonorrhoeae<\/em> has integrated human genetic material into its own genome, and that this development is of recent evolutionary origin. Horizontal (inter-species) transfer of genetic material is, of course, the means by which these organisms evolve – along with vertical (inter-generation) transfer.\u00a0 But transfer from mammal to bacterium has not, it seems, been recorded \u2013 until now.<\/p>\n

There is actually a good reason why it should be\u00a0 Neisseria gonorrhoeae <\/em>of all bacteria that gains this place in history. Its exclusive relationship to its human host seems to have been a characteristic that has facilitated the identification of the transferred genetic material.\u00a0 As for whether it derives any advantage from this particular adaptation, or whether it offers a clue to the gonococcus’s nimble ability to continually adapt and survive in its human host, we really don\u2019t know yet. But this discovery may turn out to have important implications for our future understanding of its success.<\/p>\n

Mark T.Anderson and H. Steven Seifert, \u201cOpportunity and Means: Horizontal Gene Transfer from the Human Host to a Bacterial Pathogen\u201d, mBio<\/em> 2011<\/p>\n

http:\/\/www.asm.org\/<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

Neisseria gonorrhoeae is a nimble bacterium, and past master at adapting itself to resist the challenge of our antibiotics.\u00a0 So maybe we shouldn\u2019t be surprised at this latest accolade: to have been the first proven case of horizontal gene transfer (HGT) between organisms as disparate as the bacterium and a human being!\u00a0 A recent study […]<\/p>\n

Read More…<\/a><\/p>\n","protected":false},"author":152,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[2103],"tags":[],"class_list":["post-240","post","type-post","status-publish","format-standard","hentry","category-gonorrhoea"],"yoast_head":"\nSo the \u201cclap\u201d has a human side! - Sexually Transmitted Infections<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/blogs.bmj.com\/sti\/2011\/03\/02\/so-the-\u201cclap\u201d-has-a-human-side\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"So the \u201cclap\u201d has a human side! - Sexually Transmitted Infections\" \/>\n<meta property=\"og:description\" content=\"Neisseria gonorrhoeae is a nimble bacterium, and past master at adapting itself to resist the challenge of our antibiotics.\u00a0 So maybe we shouldn\u2019t be surprised at this latest accolade: to have been the first proven case of horizontal gene transfer (HGT) between organisms as disparate as the bacterium and a human being!\u00a0 A recent study [...]Read More...\" \/>\n<meta property=\"og:url\" content=\"https:\/\/blogs.bmj.com\/sti\/2011\/03\/02\/so-the-\u201cclap\u201d-has-a-human-side\/\" \/>\n<meta property=\"og:site_name\" content=\"Sexually Transmitted Infections\" \/>\n<meta property=\"article:published_time\" content=\"2011-03-02T21:55:12+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2011-05-02T21:11:01+00:00\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/blogs.bmj.com\\\/sti\\\/2011\\\/03\\\/02\\\/so-the-%e2%80%9cclap%e2%80%9d-has-a-human-side\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/blogs.bmj.com\\\/sti\\\/2011\\\/03\\\/02\\\/so-the-%e2%80%9cclap%e2%80%9d-has-a-human-side\\\/\"},\"author\":{\"name\":\"\",\"@id\":\"\"},\"headline\":\"So the \u201cclap\u201d has a human side!\",\"datePublished\":\"2011-03-02T21:55:12+00:00\",\"dateModified\":\"2011-05-02T21:11:01+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/blogs.bmj.com\\\/sti\\\/2011\\\/03\\\/02\\\/so-the-%e2%80%9cclap%e2%80%9d-has-a-human-side\\\/\"},\"wordCount\":248,\"commentCount\":0,\"publisher\":{\"@id\":\"https:\\\/\\\/blogs.bmj.com\\\/sti\\\/#organization\"},\"articleSection\":[\"Gonorrhoea\"],\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"CommentAction\",\"name\":\"Comment\",\"target\":[\"https:\\\/\\\/blogs.bmj.com\\\/sti\\\/2011\\\/03\\\/02\\\/so-the-%e2%80%9cclap%e2%80%9d-has-a-human-side\\\/#respond\"]}]},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/blogs.bmj.com\\\/sti\\\/2011\\\/03\\\/02\\\/so-the-%e2%80%9cclap%e2%80%9d-has-a-human-side\\\/\",\"url\":\"https:\\\/\\\/blogs.bmj.com\\\/sti\\\/2011\\\/03\\\/02\\\/so-the-%e2%80%9cclap%e2%80%9d-has-a-human-side\\\/\",\"name\":\"So the \u201cclap\u201d has a human side! 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