{"id":228,"date":"2011-02-16T21:37:56","date_gmt":"2011-02-16T21:37:56","guid":{"rendered":"https:\/\/blogs.bmj.com\/sti\/?p=228"},"modified":"2011-05-02T21:11:51","modified_gmt":"2011-05-02T21:11:51","slug":"the-case-for-better-hepatitis-c-surveillance-in-hiv-infected-men","status":"publish","type":"post","link":"https:\/\/blogs.bmj.com\/sti\/2011\/02\/16\/the-case-for-better-hepatitis-c-surveillance-in-hiv-infected-men\/","title":{"rendered":"The case for better Hepatitis C surveillance in HIV-infected men"},"content":{"rendered":"

Far more needs to be done to diagnose incident Hepatitis C (HCV) in HIV-infected men in the era highly active anti-retroviral therapy (HAART).\u00a0 This is the message coming out of a recent US long-term study (http:\/\/cid.oxfordjournals.org\/content\/early\/2011\/01\/29\/cid.ciq201.full)<\/a>.<\/p>\n

Current US Public Health Service HIV guidelines endorse HCV testing only at initial HIV diagnosis \u2013 maybe because of low rates of HCV transmission in heterosexual couples.\u00a0 But, according to the authors of this study, this does not respond to the importance of male to male transmission, and strong possibility, indicated by this study and others, that intravenous drug use is not the dominant means of transmission.\u00a0 HCV in HIV-infected people is a serious cause of morbidity and mortality, but clinically silent until an advanced stage.\u00a0 In order to be able to intervene at the acute stage where the disease is responsive to treatment, and to contain epidemiological spread, it is imperative, the authors argue, to develop new approaches to diagnosis and treatment.<\/p>\n

Of the 1830 men engaged in the study (94% in HAART) 36 sero-converted, amounting to an incidence of .51 cases in 100 person years.\u00a0 Sero-conversion was also associated with IDU history (25%) and poor HIV suppression.\u00a0 This suggests nonparenteral transmission, and possibly a tendency to poor adherence to HAART, suggestive of risk-taking behaviour.<\/p>\n

What would be the optimal interval of routine HCV anti-body surveillance for at risk HIV infected persons?\u00a0 This remains to be determined \u2013 but our authors cite the recommendation of the New York State Department of Health AIDS Department, which is for annual serological testing.<\/p>\n

Lynn E. Taylor, \u201cIncident Hepatatis C Virus Infection among US HIV Infected men enrolled in Clinical Trials\u201d, Clinical Infectious Diseases, March 2011<\/p>\n

http:\/\/cid.oxfordjournals.org\/content\/early\/2011\/01\/29\/cid.ciq201.full<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

Far more needs to be done to diagnose incident Hepatitis C (HCV) in HIV-infected men in the era highly active anti-retroviral therapy (HAART).\u00a0 This is the message coming out of a recent US long-term study (http:\/\/cid.oxfordjournals.org\/content\/early\/2011\/01\/29\/cid.ciq201.full). Current US Public Health Service HIV guidelines endorse HCV testing only at initial HIV diagnosis \u2013 maybe because of […]<\/p>\n

Read More…<\/a><\/p>\n","protected":false},"author":152,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[2042,1613],"tags":[],"class_list":["post-228","post","type-post","status-publish","format-standard","hentry","category-hiv-care","category-sexual-health-services"],"yoast_head":"\nThe case for better Hepatitis C surveillance in HIV-infected men - Sexually Transmitted Infections<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/blogs.bmj.com\/sti\/2011\/02\/16\/the-case-for-better-hepatitis-c-surveillance-in-hiv-infected-men\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"The case for better Hepatitis C surveillance in HIV-infected men - Sexually Transmitted Infections\" \/>\n<meta property=\"og:description\" content=\"Far more needs to be done to diagnose incident Hepatitis C (HCV) in HIV-infected men in the era highly active anti-retroviral therapy (HAART).\u00a0 This is the message coming out of a recent US long-term study (http:\/\/cid.oxfordjournals.org\/content\/early\/2011\/01\/29\/cid.ciq201.full). 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