{"id":1016,"date":"2015-01-20T12:00:43","date_gmt":"2015-01-20T12:00:43","guid":{"rendered":"https:\/\/blogs.bmj.com\/spcare\/?p=1016"},"modified":"2015-01-13T15:28:39","modified_gmt":"2015-01-13T15:28:39","slug":"news-and-updates-from-www-palliativedrugs-com-72","status":"publish","type":"post","link":"https:\/\/blogs.bmj.com\/spcare\/2015\/01\/20\/news-and-updates-from-www-palliativedrugs-com-72\/","title":{"rendered":"News and updates from www.palliativedrugs.com"},"content":{"rendered":"<p>Selected items from the News and Latest Additions sections of<a href=\"%20www.palliativedrugs.com\" target=\"_blank\"> www.palliativedrugs.com<\/a>, the world\u2019s leading palliative care website.<\/p>\n<p>&nbsp;<\/p>\n<p><strong>Safety Alerts<\/strong><\/p>\n<p><strong>Gabapentin and Pregabalin Potential for Misuse<\/strong><br \/>\nPublic Health England and NHS England have published advice for prescribers on the risk of misuse of gabapentin and pregabalin. For more information, click <a href=\"https:\/\/www.gov.uk\/government\/uploads\/system\/uploads\/attachment_data\/file\/385791\/PHE-NHS_England_pregabalin_and_gabapentin_advice_Dec_2014.pdf\" target=\"_blank\">here<\/a>.<\/p>\n<p>&nbsp;<\/p>\n<p><strong>Hot Topics<\/strong><\/p>\n<p><strong>Drugs and Driving, MHRA Clarification<\/strong><br \/>\nThe new offence of driving with certain controlled drugs above specified limits in the blood which comes into force in March 2015 (see our news item <a href=\"http:\/\/www.palliativedrugs.com\/news\/july\/new-drug-driving-offence-department-for-transport-guidance.html\" target=\"_blank\">9 July 2014<\/a>) is for England, Wales and Scotland only. In Northern Ireland a similar offence is under consideration. MHRA have produced a <a href=\"http:\/\/www.mhra.gov.uk\/home\/groups\/dsu\/documents\/publication\/con437439.pdf\" target=\"_blank\">Patient Information Leaflet<\/a>. For more information, click <a href=\"http:\/\/www.mhra.gov.uk\/Safetyinformation\/DrugSafetyUpdate\/CON462303\" target=\"_blank\">here<\/a>.<\/p>\n<p><strong>New Scottish Palliative Care Guidelines<\/strong><br \/>\nThe new Scottish Palliative Care Guidelines have been launched. These national guidelines replace the previous pain &amp; symptom control section of the Lothian Palliative Care Guidelines (2010). For more information, click <a href=\"http:\/\/www.palliativecareguidelines.scot.nhs.uk\/\" target=\"_blank\">here<\/a>.<\/p>\n<p><strong>New Medicines Compliance Aid Database<\/strong><br \/>\nUK Medicines Information (UKMi) has launched an open access medicines compliance aid database, which makes recommendations on the suitability of transferring solid dose formulations from the manufacturers\u2019 original packaging into multi-compartment compliance aids. For more information, click <a href=\"http:\/\/www.ukmi.nhs.uk\/applications\/mca\/\" target=\"_blank\">here<\/a>.<\/p>\n<p><strong>APPM Master Formulary 2015 3rd Edition Now Available<\/strong><br \/>\nThe 3rd edition of the Association for Paediatric Palliative Medicine (APPM) Master Formulary is now available and can be downloaded from the APPM website <a href=\"http:\/\/www.appm.org.uk\/10.html\" target=\"_blank\">here<\/a>.<\/p>\n<p>&nbsp;<\/p>\n<p><strong>Drug Updates<\/strong><\/p>\n<p><strong>FDA Approves Additional Indication for Denosumab<\/strong><br \/>\nThe US FDA has approved denosumab (Xgeva; Amgen) for the treatment of hypercalcaemia of malignancy refractory to bisphosphonate therapy. In the UK, denosumab is currently only authorized for prevention of skeletal related events in adults with bone metastases from solid tumours; and treatment of adults and skeletally mature adolescents with giant cell tumour of bone that is unresectable or where surgical resection is likely to result in severe morbidity. For US Prescribing Information, click <a href=\"http:\/\/pi.amgen.com\/united_states\/xgeva\/xgeva_pi.pdf\" target=\"_blank\">here<\/a>. For the UK SPC, click <a href=\"http:\/\/www.medicines.org.uk\/emc\/medicine\/24755\" target=\"_blank\">here<\/a>.<\/p>\n<p><strong>Haldol Injection Discontinued<\/strong><br \/>\nThe Haldol brand of haloperidol injection 5mg\/mL (Janssen-Cilag) has been discontinued. Generic haloperidol 5mg\/mL injections are available.<\/p>\n<p><strong>Rivotril Tablets Discontinued<\/strong><br \/>\nThe Rivotril brand of clonazepam 500microgram and 2mg tablets (Roche) has been discontinued. Generic clonazepam 500microgram and 2mg tablets are available.<\/p>\n<p><strong>Macrodantin Capsules Discontinued<br \/>\n<\/strong>The Macrodantin brand of nitrofurantoin 50mg and 100mg hard capsules (Amdipharm Mercury) has been discontinued. Generic nitrofurantoin 50mg and 100mg tablets are available.<\/p>\n<p>&nbsp;<\/p>\n<p><strong>Latest Additions<\/strong><\/p>\n<p><strong>Use of Dexamethasone Formulations in Palliative Care: a palliativedrugs.com Response to Recent Changes<\/strong><br \/>\nFollowing the recent changes in the formulation of one of the dexamethasone injections in the UK (see our news item <a href=\"http:\/\/www.palliativedrugs.com\/news\/october\/dexamethasone-4mgml-injection-changes.html\" target=\"_blank\">21 October 2014<\/a>), we have put together a palliativedrugs.com summary in order to clarify the situation on the use of dexamethasone formulations in adults in palliative care. This can be downloaded <a href=\"http:\/\/www.palliativedrugs.com\/download\/dexamethasone_injection_changes_V11_141218_aw_final.pdf\" target=\"_blank\">here<\/a>. The on-line PCF systemic corticosteroids monograph will be updated shortly to reflect this guidance.<\/p>\n<p>In addition, there is now a manufacturer&#8217;s supply problem with the Hospira brand of dexamethasone base 3.3mg\/mL, 1mL ampoules, which is not expected to be resolved until January 2015.<\/p>\n<p>&nbsp;<\/p>\n<p><strong>Survey Results<\/strong><\/p>\n<p><strong>Website Satisfaction Survey Winners and Results<\/strong><br \/>\nResults from our satisfaction survey (<a href=\"http:\/\/www.palliativedrugs.com\/download\/141217_satisfaction_survey2014_v02_sc_final.pdf\" target=\"_blank\">October \u2013 November 2014<\/a>).<\/p>\n<p>&nbsp;<\/p>\n<p>Prepared by Sarah Charlesworth and Andrew Wilcock<!--TrendMD v2.4.8--><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Selected items from the News and Latest Additions sections of www.palliativedrugs.com, the world\u2019s leading palliative care website. &nbsp; Safety Alerts Gabapentin and Pregabalin Potential for Misuse Public Health England and NHS England have published advice for prescribers on the risk of misuse of gabapentin and pregabalin. For more information, click here. &nbsp; Hot Topics Drugs [&#8230;]<\/p>\n<p><a class=\"btn btn-secondary understrap-read-more-link\" href=\"https:\/\/blogs.bmj.com\/spcare\/2015\/01\/20\/news-and-updates-from-www-palliativedrugs-com-72\/\">Read More&#8230;<\/a><\/p>\n","protected":false},"author":201,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[2833],"tags":[],"class_list":["post-1016","post","type-post","status-publish","format-standard","hentry","category-updates-from-www-palliativedrugs-com"],"_links":{"self":[{"href":"https:\/\/blogs.bmj.com\/spcare\/wp-json\/wp\/v2\/posts\/1016","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/blogs.bmj.com\/spcare\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/blogs.bmj.com\/spcare\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/blogs.bmj.com\/spcare\/wp-json\/wp\/v2\/users\/201"}],"replies":[{"embeddable":true,"href":"https:\/\/blogs.bmj.com\/spcare\/wp-json\/wp\/v2\/comments?post=1016"}],"version-history":[{"count":0,"href":"https:\/\/blogs.bmj.com\/spcare\/wp-json\/wp\/v2\/posts\/1016\/revisions"}],"wp:attachment":[{"href":"https:\/\/blogs.bmj.com\/spcare\/wp-json\/wp\/v2\/media?parent=1016"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/blogs.bmj.com\/spcare\/wp-json\/wp\/v2\/categories?post=1016"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/blogs.bmj.com\/spcare\/wp-json\/wp\/v2\/tags?post=1016"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}