{"id":2812,"date":"2014-08-14T09:50:19","date_gmt":"2014-08-14T08:50:19","guid":{"rendered":"https:\/\/blogs.bmj.com\/medical-ethics\/?p=2812"},"modified":"2014-08-14T09:50:19","modified_gmt":"2014-08-14T08:50:19","slug":"advance-directives-critical-interests-and-dementia-research","status":"publish","type":"post","link":"https:\/\/blogs.bmj.com\/medical-ethics\/2014\/08\/14\/advance-directives-critical-interests-and-dementia-research\/","title":{"rendered":"Advance Directives, Critical Interests, and Dementia Research"},"content":{"rendered":"<p><strong>Guest post by Tom Buller,\u00a0Illinois State University<br \/>\n<\/strong><\/p>\n<p><span style=\"text-decoration: underline;color: #0000ff\"><a href=\"http:\/\/jme.bmj.com\/content\/early\/2014\/08\/12\/medethics-2014-102024.full\"><span style=\"text-decoration: underline;color: #0000ff\">In my paper<\/span><\/a><\/span>, \u201cAdvance Directives, Critical Interests, and Dementia Research&#8221;, I investigate whether advance directives can be applied in the context of dementia research. Consider, for the sake of argument, the following fictional case. William, a 77-year-old man who has moderate to severe dementia. When he was first diagnosed and while still competent he declared on many occasions that he wished to do all he could to help future sufferers of the disease and find a cure for Alzheimer\u2019s, and he repeatedly said that he very much wanted to participate in any clinical trials, even those that might involve hardship and risk. With the full agreement of his family William was enrolled in a five-year clinical trial testing a new treatment for Alzheimer\u2019s that involves.<\/p>\n<p>I think it can be legitimately argued that William has the right to make a future-binding decision to participate in the above trial, for the reasons that justify the use of a decision in the treatment context also apply in the present research context. First, William\u2019s beneficent desire to help future sufferers of Alzheimer\u2019s is part and parcel of his character and what gives his life value. Second, the principle of precedent autonomy is not invalidated by the fact the person is encouraging, rather than, refusing intervention, and that the chosen course of action requires the assistance of others. Third, William\u2019s decision is not invalidated by the fact that it is motivated by beneficence rather than self-interest.<\/p>\n<p>If this analysis is correct, then it would seem that there are good reasons to think that a competent person has the right to decide to participate in future research once competence has been lost, even research that is (significantly) greater than minimal risk.<\/p>\n<p>&nbsp;<\/p>\n<p><em>Read the full paper online first\u00a0<span style=\"text-decoration: underline\"><span style=\"color: #0000ff\"><a href=\"http:\/\/jme.bmj.com\/content\/early\/2014\/08\/12\/medethics-2014-102024.full\"><span style=\"color: #0000ff;text-decoration: underline\">here<\/span><\/a><\/span><\/span><\/em>.<!--TrendMD v2.4.8--><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Guest post by Tom Buller,\u00a0Illinois State University In my paper, \u201cAdvance Directives, Critical Interests, and Dementia Research&#8221;, I investigate whether advance directives can be applied in the context of dementia research. Consider, for the sake of argument, the following fictional case. William, a 77-year-old man who has moderate to severe dementia. When he was first [&#8230;]<\/p>\n<p><a class=\"btn btn-secondary understrap-read-more-link\" href=\"https:\/\/blogs.bmj.com\/medical-ethics\/2014\/08\/14\/advance-directives-critical-interests-and-dementia-research\/\">Read More&#8230;<\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[968,2153,443,328],"tags":[317],"class_list":["post-2812","post","type-post","status-publish","format-standard","hentry","category-clinical-ethics","category-guest-post","category-jme","category-philosophy","tag-research"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.6 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Advance Directives, Critical Interests, and Dementia Research - Journal of Medical Ethics blog<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/blogs.bmj.com\/medical-ethics\/2014\/08\/14\/advance-directives-critical-interests-and-dementia-research\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Advance Directives, Critical Interests, and Dementia Research - Journal of Medical Ethics blog\" \/>\n<meta property=\"og:description\" content=\"Guest post by Tom Buller,\u00a0Illinois State University In my paper, \u201cAdvance Directives, Critical Interests, and Dementia Research&#8221;, I investigate whether advance directives can be applied in the context of dementia research. 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