{"id":431,"date":"2014-08-06T12:15:52","date_gmt":"2014-08-06T12:15:52","guid":{"rendered":"https:\/\/blogs.bmj.com\/jnnp\/?p=431"},"modified":"2014-08-06T12:15:52","modified_gmt":"2014-08-06T12:15:52","slug":"glutamate-and-memory-a-novel-paradigm-in-ms","status":"publish","type":"post","link":"https:\/\/blogs.bmj.com\/jnnp\/2014\/08\/06\/glutamate-and-memory-a-novel-paradigm-in-ms\/","title":{"rendered":"Glutamate and memory: A novel paradigm in MS"},"content":{"rendered":"

Glutamate is a major excitatory\u00a0 neurotransmitter in the human brain vital for multiple functions, including memory and cognition.\u00a0 Importantly, excessive glutamate activity may be harmful<\/p>\n

to the CNS, leading to neurodegeneration.\u00a0 In this issue of JNNP, Muhlert and colleagues report a link between glutamate levels and memory, a unique link in MS.\u00a0 Given that forgetfulness is a common symptom in MS, the possibility of using glutamate agonist, or enhancer of the glutamatergic system,\u00a0\u00a0 has real potential.<\/p>\n

 <\/p>\n

Read more at :\u00a0 http:\/\/jnnp.bmj.com\/content\/85\/8\/833.abstract<\/p>\n

Memory in multiple sclerosis is linked to glutamate concentration in grey matter regions<\/h1>\n

\"Open<\/a><\/span><\/p>\n

\n
    \n
  1. Nils Muhlert<\/a><\/span>1<\/a>,<\/span>2<\/a>,<\/li>\n
  2. Matteo Atzori<\/a><\/span>3<\/a>,<\/span>4<\/a>,<\/li>\n
  3. Enrico De Vita<\/a><\/span>5<\/a>,<\/span>6<\/a>,<\/li>\n
  4. David L Thomas<\/a><\/span>6<\/a>,<\/li>\n
  5. Rebecca S Samson<\/a><\/span>1<\/a>,<\/li>\n
  6. Claudia A M Wheeler-Kingshott<\/a><\/span>1<\/a>,<\/li>\n
  7. Jeroen J G Geurts<\/a><\/span>7<\/a>,<\/li>\n
  8. David H Miller<\/a><\/span>1<\/a>,<\/span>8<\/a>,<\/li>\n
  9. Alan J Thompson<\/a><\/span>3<\/a>,<\/span>8<\/a>,<\/li>\n
  10. Olga Ciccarelli<\/a><\/span>3<\/a>,<\/span>8<\/a><\/li>\n<\/ol>\n<\/div>\n

     <\/p>\n","protected":false},"excerpt":{"rendered":"

    Glutamate is a major excitatory\u00a0 neurotransmitter in the human brain vital for multiple functions, including memory and cognition.\u00a0 Importantly, excessive glutamate activity may be harmful to the CNS, leading to neurodegeneration.\u00a0 In this issue of JNNP, Muhlert and colleagues report a link between glutamate levels and memory, a unique link in MS.\u00a0 Given that forgetfulness […]<\/p>\n

    Read More…<\/a><\/p>\n","protected":false},"author":160,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":["post-431","post","type-post","status-publish","format-standard","hentry","category-uncategorized"],"yoast_head":"\nGlutamate and memory: A novel paradigm in MS - JNNP blog<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/blogs.bmj.com\/jnnp\/2014\/08\/06\/glutamate-and-memory-a-novel-paradigm-in-ms\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Glutamate and memory: A novel paradigm in MS - JNNP blog\" \/>\n<meta property=\"og:description\" content=\"Glutamate is a major excitatory\u00a0 neurotransmitter in the human brain vital for multiple functions, including memory and cognition.\u00a0 Importantly, excessive glutamate activity may be harmful to the CNS, leading to neurodegeneration.\u00a0 In this issue of JNNP, Muhlert and colleagues report a link between glutamate levels and memory, a unique link in MS.\u00a0 Given that forgetfulness [...]Read More...\" \/>\n<meta property=\"og:url\" content=\"https:\/\/blogs.bmj.com\/jnnp\/2014\/08\/06\/glutamate-and-memory-a-novel-paradigm-in-ms\/\" \/>\n<meta property=\"og:site_name\" content=\"JNNP blog\" \/>\n<meta property=\"article:published_time\" content=\"2014-08-06T12:15:52+00:00\" \/>\n<meta property=\"og:image\" content=\"http:\/\/jnnp.bmj.com\/publisher\/icons\/open-access-logo.gif\" \/>\n<meta name=\"author\" content=\"Steve Vucic, Web Editor\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Steve Vucic, Web Editor\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/blogs.bmj.com\\\/jnnp\\\/2014\\\/08\\\/06\\\/glutamate-and-memory-a-novel-paradigm-in-ms\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/blogs.bmj.com\\\/jnnp\\\/2014\\\/08\\\/06\\\/glutamate-and-memory-a-novel-paradigm-in-ms\\\/\"},\"author\":{\"name\":\"Steve Vucic, Web Editor\",\"@id\":\"https:\\\/\\\/blogs.bmj.com\\\/jnnp\\\/#\\\/schema\\\/person\\\/5b9f797a427758da9d63182166e6458c\"},\"headline\":\"Glutamate and memory: A novel paradigm in MS\",\"datePublished\":\"2014-08-06T12:15:52+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/blogs.bmj.com\\\/jnnp\\\/2014\\\/08\\\/06\\\/glutamate-and-memory-a-novel-paradigm-in-ms\\\/\"},\"wordCount\":137,\"commentCount\":0,\"publisher\":{\"@id\":\"https:\\\/\\\/blogs.bmj.com\\\/jnnp\\\/#organization\"},\"image\":{\"@id\":\"https:\\\/\\\/blogs.bmj.com\\\/jnnp\\\/2014\\\/08\\\/06\\\/glutamate-and-memory-a-novel-paradigm-in-ms\\\/#primaryimage\"},\"thumbnailUrl\":\"http:\\\/\\\/jnnp.bmj.com\\\/publisher\\\/icons\\\/open-access-logo.gif\",\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"CommentAction\",\"name\":\"Comment\",\"target\":[\"https:\\\/\\\/blogs.bmj.com\\\/jnnp\\\/2014\\\/08\\\/06\\\/glutamate-and-memory-a-novel-paradigm-in-ms\\\/#respond\"]}]},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/blogs.bmj.com\\\/jnnp\\\/2014\\\/08\\\/06\\\/glutamate-and-memory-a-novel-paradigm-in-ms\\\/\",\"url\":\"https:\\\/\\\/blogs.bmj.com\\\/jnnp\\\/2014\\\/08\\\/06\\\/glutamate-and-memory-a-novel-paradigm-in-ms\\\/\",\"name\":\"Glutamate and memory: A novel paradigm in MS - 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