{"id":399,"date":"2014-06-05T03:25:17","date_gmt":"2014-06-05T03:25:17","guid":{"rendered":"https:\/\/blogs.bmj.com\/jnnp\/?p=399"},"modified":"2014-06-05T03:27:09","modified_gmt":"2014-06-05T03:27:09","slug":"reduction-in-blood-pressure-is-it-really-bad-in-acute-stroke","status":"publish","type":"post","link":"https:\/\/blogs.bmj.com\/jnnp\/2014\/06\/05\/reduction-in-blood-pressure-is-it-really-bad-in-acute-stroke\/","title":{"rendered":"Reduction in blood pressure: Does the J curve still talk??"},"content":{"rendered":"<p>A \u2018J-curve\u2019 association between blood pressure (BP) and stroke has been previously reported, whereby highest and the lowest BPs were associated with increased risks of recurrent stroke among patients with recent ischaemic stroke.\u00a0 Clearly, such a finding has management implications.\u00a0 In an upcoming issue of JNNP,\u00a0the PROGRESS Collaborative Group dismiss this myth.\u00a0 Namely, large reductions of BP (&gt; 20 mmHg) WERE NOT associated with an increased risk of any types of stroke, with the annual incidence hovering between 2-3%.<\/p>\n<p>&nbsp;<\/p>\n<p>So I guess, the answer may well be to treat hypertension aggressively, but not to the point of dizziness.<\/p>\n<p>&nbsp;<\/p>\n<p>Read more:\u00a0 http:\/\/jnnp.bmj.com\/content\/early\/2014\/05\/14\/jnnp-2014-307856.full<\/p>\n<p>&nbsp;<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"shrinkToFit decoded\" src=\"http:\/\/jnnp.bmj.com\/content\/early\/2014\/05\/14\/jnnp-2014-307856\/F1.large.jpg\" alt=\"http:\/\/jnnp.bmj.com\/content\/early\/2014\/05\/14\/jnnp-2014-307856\/F1.large.jpg\" width=\"452\" height=\"197\" \/><\/p>\n<p>&nbsp;<\/p>\n<h1 id=\"article-title-1\">Degree of blood pressure reduction and recurrent stroke: the PROGRESS trial<\/h1>\n<div class=\"contributors\">\n<ol id=\"contrib-group-1\" class=\"contributor-list\">\n<li id=\"contrib-1\" class=\"contributor\"><span class=\"name\"><a class=\"name-search\" href=\"http:\/\/jnnp.bmj.com\/search?author1=Hisatomi+Arima&amp;sortspec=date&amp;submit=Submit\">Hisatomi Arima<\/a><\/span><a id=\"xref-aff-1-1\" class=\"xref-aff\" href=\"http:\/\/jnnp.bmj.com\/content\/early\/2014\/05\/14\/jnnp-2014-307856.full#aff-1\">1<\/a>,<\/li>\n<li id=\"contrib-2\" class=\"contributor\"><span class=\"name\"><a class=\"name-search\" href=\"http:\/\/jnnp.bmj.com\/search?author1=Craig+Anderson&amp;sortspec=date&amp;submit=Submit\">Craig Anderson<\/a><\/span><a id=\"xref-aff-1-2\" class=\"xref-aff\" href=\"http:\/\/jnnp.bmj.com\/content\/early\/2014\/05\/14\/jnnp-2014-307856.full#aff-1\">1<\/a>,<\/li>\n<li id=\"contrib-3\" class=\"contributor\"><span class=\"name\"><a class=\"name-search\" href=\"http:\/\/jnnp.bmj.com\/search?author1=Teruo+Omae&amp;sortspec=date&amp;submit=Submit\">Teruo Omae<\/a><\/span><a id=\"xref-aff-2-1\" class=\"xref-aff\" href=\"http:\/\/jnnp.bmj.com\/content\/early\/2014\/05\/14\/jnnp-2014-307856.full#aff-2\">2<\/a>,<\/li>\n<li id=\"contrib-4\" class=\"contributor\"><span class=\"name\"><a class=\"name-search\" href=\"http:\/\/jnnp.bmj.com\/search?author1=Mark+Woodward&amp;sortspec=date&amp;submit=Submit\">Mark Woodward<\/a><\/span><a id=\"xref-aff-1-3\" class=\"xref-aff\" href=\"http:\/\/jnnp.bmj.com\/content\/early\/2014\/05\/14\/jnnp-2014-307856.full#aff-1\">1<\/a>,<\/li>\n<li id=\"contrib-5\" class=\"contributor\"><span class=\"name\"><a class=\"name-search\" href=\"http:\/\/jnnp.bmj.com\/search?author1=Stephen+MacMahon&amp;sortspec=date&amp;submit=Submit\">Stephen MacMahon<\/a><\/span><a id=\"xref-aff-1-4\" class=\"xref-aff\" href=\"http:\/\/jnnp.bmj.com\/content\/early\/2014\/05\/14\/jnnp-2014-307856.full#aff-1\">1<\/a><span class=\"xref-sep\">,<\/span><a id=\"xref-aff-3-1\" class=\"xref-aff\" href=\"http:\/\/jnnp.bmj.com\/content\/early\/2014\/05\/14\/jnnp-2014-307856.full#aff-3\">3<\/a>,<\/li>\n<li id=\"contrib-6\" class=\"contributor\"><span class=\"name\"><a class=\"name-search\" href=\"http:\/\/jnnp.bmj.com\/search?author1=Giuseppe+Mancia&amp;sortspec=date&amp;submit=Submit\">Giuseppe Mancia<\/a><\/span><a id=\"xref-aff-4-1\" class=\"xref-aff\" href=\"http:\/\/jnnp.bmj.com\/content\/early\/2014\/05\/14\/jnnp-2014-307856.full#aff-4\">4<\/a>,<\/li>\n<li id=\"contrib-7\" class=\"contributor\"><span class=\"name\"><a class=\"name-search\" href=\"http:\/\/jnnp.bmj.com\/search?author1=Marie-Germaine+Bousser&amp;sortspec=date&amp;submit=Submit\">Marie-Germaine Bousser<\/a><\/span><a id=\"xref-aff-5-1\" class=\"xref-aff\" href=\"http:\/\/jnnp.bmj.com\/content\/early\/2014\/05\/14\/jnnp-2014-307856.full#aff-5\">5<\/a>,<\/li>\n<li id=\"contrib-8\" class=\"contributor\"><span class=\"name\"><a class=\"name-search\" href=\"http:\/\/jnnp.bmj.com\/search?author1=Christophe+Tzourio&amp;sortspec=date&amp;submit=Submit\">Christophe Tzourio<\/a><\/span><a id=\"xref-aff-6-1\" class=\"xref-aff\" href=\"http:\/\/jnnp.bmj.com\/content\/early\/2014\/05\/14\/jnnp-2014-307856.full#aff-6\">6<\/a><span class=\"xref-sep\">,<\/span><a id=\"xref-aff-7-1\" class=\"xref-aff\" href=\"http:\/\/jnnp.bmj.com\/content\/early\/2014\/05\/14\/jnnp-2014-307856.full#aff-7\">7<\/a>,<\/li>\n<li id=\"contrib-9\" class=\"contributor\"><span class=\"name\"><a class=\"name-search\" href=\"http:\/\/jnnp.bmj.com\/search?author1=Stephen+Harrap&amp;sortspec=date&amp;submit=Submit\">Stephen Harrap<\/a><\/span><a id=\"xref-aff-8-1\" class=\"xref-aff\" href=\"http:\/\/jnnp.bmj.com\/content\/early\/2014\/05\/14\/jnnp-2014-307856.full#aff-8\">8<\/a>,<\/li>\n<li id=\"contrib-10\" class=\"contributor\"><span class=\"name\"><a class=\"name-search\" href=\"http:\/\/jnnp.bmj.com\/search?author1=Lisheng+Liu&amp;sortspec=date&amp;submit=Submit\">Lisheng Liu<\/a><\/span><a id=\"xref-aff-9-1\" class=\"xref-aff\" href=\"http:\/\/jnnp.bmj.com\/content\/early\/2014\/05\/14\/jnnp-2014-307856.full#aff-9\">9<\/a>,<\/li>\n<li id=\"contrib-11\" class=\"contributor\"><span class=\"name\"><a class=\"name-search\" href=\"http:\/\/jnnp.bmj.com\/search?author1=Bruce+Neal&amp;sortspec=date&amp;submit=Submit\">Bruce Neal<\/a><\/span><a id=\"xref-aff-1-5\" class=\"xref-aff\" href=\"http:\/\/jnnp.bmj.com\/content\/early\/2014\/05\/14\/jnnp-2014-307856.full#aff-1\">1<\/a>,<\/li>\n<li id=\"contrib-12\" class=\"contributor\"><span class=\"name\"><a class=\"name-search\" href=\"http:\/\/jnnp.bmj.com\/search?author1=John+Chalmers&amp;sortspec=date&amp;submit=Submit\">John Chalmers<\/a><\/span><a id=\"xref-aff-1-6\" class=\"xref-aff\" href=\"http:\/\/jnnp.bmj.com\/content\/early\/2014\/05\/14\/jnnp-2014-307856.full#aff-1\">1<\/a>,<\/li>\n<li id=\"contrib-13\" class=\"last\"><span id=\"collab-1\" class=\"collab\">for the PROGRESS Collaborative Group<\/span><\/li>\n<\/ol>\n<p><cite><span id=\"article-slug-jnl-abbr\"><abbr class=\"slug-jnl-abbrev\" title=\"Journal of Neurology, Neurosurgery &amp; Psychiatry\"> J Neurol Neurosurg Psychiatry<\/abbr> <\/span> <span class=\"slug-doi\" title=\"10.1136\/jnnp-2014-307856\"> doi:10.1136\/jnnp-2014-307856 <\/span><\/cite><\/p>\n<\/div>\n<p><!--TrendMD v2.4.8--><\/p>\n","protected":false},"excerpt":{"rendered":"<p>A \u2018J-curve\u2019 association between blood pressure (BP) and stroke has been previously reported, whereby highest and the lowest BPs were associated with increased risks of recurrent stroke among patients with recent ischaemic stroke.\u00a0 Clearly, such a finding has management implications.\u00a0 In an upcoming issue of JNNP,\u00a0the PROGRESS Collaborative Group dismiss this myth.\u00a0 Namely, large reductions [&#8230;]<\/p>\n<p><a class=\"btn btn-secondary understrap-read-more-link\" href=\"https:\/\/blogs.bmj.com\/jnnp\/2014\/06\/05\/reduction-in-blood-pressure-is-it-really-bad-in-acute-stroke\/\">Read More&#8230;<\/a><\/p>\n","protected":false},"author":160,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":["post-399","post","type-post","status-publish","format-standard","hentry","category-uncategorized"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.4 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Reduction in blood pressure: Does the J curve still talk?? - JNNP blog<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/blogs.bmj.com\/jnnp\/2014\/06\/05\/reduction-in-blood-pressure-is-it-really-bad-in-acute-stroke\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Reduction in blood pressure: Does the 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