{"id":379,"date":"2014-05-03T08:57:19","date_gmt":"2014-05-03T08:57:19","guid":{"rendered":"https:\/\/blogs.bmj.com\/jnnp\/?p=379"},"modified":"2014-05-03T08:57:19","modified_gmt":"2014-05-03T08:57:19","slug":"perivascular-hyperintensities-and-cognitive-impairment-no-link","status":"publish","type":"post","link":"https:\/\/blogs.bmj.com\/jnnp\/2014\/05\/03\/perivascular-hyperintensities-and-cognitive-impairment-no-link\/","title":{"rendered":"Perivascular hyperintensities and cognitive impairment: No link"},"content":{"rendered":"

The detection of T2 hyperintensities within the CNS, often termed small vessel disease, has been linked to development of cognitive impairment and is though to be driven by vascular risk factors such as hypertension.\u00a0 MRI-visible perivascular spaces (PVS), see fig below, appear to be reliable MRI bio-markers of small vessel disease and have been associated with development of dementia and cognitive dysfunction in the elderly.\u00a0 In this issue of JNNP, an elegant study by Hurford and colleagues report an absence of any association between PVS and cognitive impairment.\u00a0 Interestingly, hypertension was a risk factor for PVS occurrence.<\/p>\n

 <\/p>\n

What does this, however, mean?\u00a0 Are the lesions in the wrong place for dementia, is a critical lesion load required for dementia.<\/p>\n

 <\/p>\n

READ MORE AT:\u00a0 http:\/\/jnnp.bmj.com\/content\/85\/5\/522.full<\/strong><\/em><\/p>\n

 <\/p>\n

\"\"<\/p>\n

Perivascular space in white square.\u00a0 PVS are differentiated from lacunae by the smaller size (< 3 mm for PVS) and being a sharpy delineated structure of CSF (dots or lines)<\/p>\n

that follow the plane of the small blood vessel, absence of surrounding hyperintensity.<\/p>\n","protected":false},"excerpt":{"rendered":"

The detection of T2 hyperintensities within the CNS, often termed small vessel disease, has been linked to development of cognitive impairment and is though to be driven by vascular risk factors such as hypertension.\u00a0 MRI-visible perivascular spaces (PVS), see fig below, appear to be reliable MRI bio-markers of small vessel disease and have been associated […]<\/p>\n

Read More…<\/a><\/p>\n","protected":false},"author":160,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":["post-379","post","type-post","status-publish","format-standard","hentry","category-uncategorized"],"yoast_head":"\nPerivascular hyperintensities and cognitive impairment: No link - JNNP blog<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/blogs.bmj.com\/jnnp\/2014\/05\/03\/perivascular-hyperintensities-and-cognitive-impairment-no-link\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Perivascular hyperintensities and cognitive impairment: No link - JNNP blog\" \/>\n<meta property=\"og:description\" content=\"The detection of T2 hyperintensities within the CNS, often termed small vessel disease, has been linked to development of cognitive impairment and is though to be driven by vascular risk factors such as hypertension.\u00a0 MRI-visible perivascular spaces (PVS), see fig below, appear to be reliable MRI bio-markers of small vessel disease and have been associated [...]Read More...\" \/>\n<meta property=\"og:url\" content=\"https:\/\/blogs.bmj.com\/jnnp\/2014\/05\/03\/perivascular-hyperintensities-and-cognitive-impairment-no-link\/\" \/>\n<meta property=\"og:site_name\" content=\"JNNP blog\" \/>\n<meta property=\"article:published_time\" content=\"2014-05-03T08:57:19+00:00\" \/>\n<meta property=\"og:image\" content=\"http:\/\/brain.oxfordjournals.org\/content\/131\/9\/2332\/F8.large.jpg\" \/>\n<meta name=\"author\" content=\"Steve Vucic, Web Editor\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Steve Vucic, Web Editor\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/blogs.bmj.com\\\/jnnp\\\/2014\\\/05\\\/03\\\/perivascular-hyperintensities-and-cognitive-impairment-no-link\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/blogs.bmj.com\\\/jnnp\\\/2014\\\/05\\\/03\\\/perivascular-hyperintensities-and-cognitive-impairment-no-link\\\/\"},\"author\":{\"name\":\"Steve Vucic, Web Editor\",\"@id\":\"https:\\\/\\\/blogs.bmj.com\\\/jnnp\\\/#\\\/schema\\\/person\\\/5b9f797a427758da9d63182166e6458c\"},\"headline\":\"Perivascular hyperintensities and cognitive impairment: No link\",\"datePublished\":\"2014-05-03T08:57:19+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/blogs.bmj.com\\\/jnnp\\\/2014\\\/05\\\/03\\\/perivascular-hyperintensities-and-cognitive-impairment-no-link\\\/\"},\"wordCount\":180,\"commentCount\":0,\"publisher\":{\"@id\":\"https:\\\/\\\/blogs.bmj.com\\\/jnnp\\\/#organization\"},\"image\":{\"@id\":\"https:\\\/\\\/blogs.bmj.com\\\/jnnp\\\/2014\\\/05\\\/03\\\/perivascular-hyperintensities-and-cognitive-impairment-no-link\\\/#primaryimage\"},\"thumbnailUrl\":\"http:\\\/\\\/brain.oxfordjournals.org\\\/content\\\/131\\\/9\\\/2332\\\/F8.large.jpg\",\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"CommentAction\",\"name\":\"Comment\",\"target\":[\"https:\\\/\\\/blogs.bmj.com\\\/jnnp\\\/2014\\\/05\\\/03\\\/perivascular-hyperintensities-and-cognitive-impairment-no-link\\\/#respond\"]}]},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/blogs.bmj.com\\\/jnnp\\\/2014\\\/05\\\/03\\\/perivascular-hyperintensities-and-cognitive-impairment-no-link\\\/\",\"url\":\"https:\\\/\\\/blogs.bmj.com\\\/jnnp\\\/2014\\\/05\\\/03\\\/perivascular-hyperintensities-and-cognitive-impairment-no-link\\\/\",\"name\":\"Perivascular hyperintensities and cognitive impairment: No link - 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