{"id":851,"date":"2016-01-08T19:26:51","date_gmt":"2016-01-08T19:26:51","guid":{"rendered":"https:\/\/blogs.bmj.com\/jmg\/?p=851"},"modified":"2026-02-25T00:18:58","modified_gmt":"2026-02-25T00:18:58","slug":"a-genetic-region-associated-with-seizure-susceptibility-is-identified-in-wolf-hischhorn-syndrome","status":"publish","type":"post","link":"https:\/\/blogs.bmj.com\/jmg\/2016\/01\/08\/a-genetic-region-associated-with-seizure-susceptibility-is-identified-in-wolf-hischhorn-syndrome\/","title":{"rendered":"A Genetic Region Associated with Seizure Susceptibility is Identified in Wolf-Hischhorn Syndrome (Contributed by Dr. Karen Ho, Dr. John Carey, and Dr. Agatino Battaglia)"},"content":{"rendered":"<p>Wolf-Hirschhorn syndrome (WHS) is a contiguous gene deletion syndrome involving variable size deletions of the short arm of chromosome 4. Approximately 90% of individuals with WHS have seizures. These seizures can be intractable and can seriously affect an individual\u2019s quality of life, especially during childhood.<\/p>\n<p>&nbsp;<\/p>\n<p>To study the genetic correlates of seizure susceptibility in WHS, we used a custom, high density chromosomal microarray platform designed for optimal detection of genomic changes associated with autism and neurodevelopmental disorders. By correlating the size and location of chromosome 4p deletions of forty-eight individuals with WHS with their seizure phenotypes, we identified a new genetic region located at the 4p terminus for seizure susceptibility. This region includes a potential candidate gene for seizure susceptibility, <em>PIGG<\/em>.<\/p>\n<p>&nbsp;<\/p>\n<p>Future studies will involve the use of new computational and statistical methods to identify more genetic correlates of WHS traits, as well as to further characterize the mechanism of seizures based on this study\u2019s findings. Such studies aim to identify potential treatments for many of the medical issues faced by individuals with WHS. (<a href=\"http:\/\/jmg.bmj.com\/content\/early\/2016\/01\/08\/jmedgenet-2015-103626\">http:\/\/jmg.bmj.com\/content\/early\/2016\/01\/08\/jmedgenet-2015-103626<\/a> )<\/p>\n<p><a href=\"https:\/\/blogs.bmj.com\/jmg\/files\/2016\/01\/Untitled.jpg\" rel=\"attachment wp-att-853\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-medium wp-image-853\" src=\"https:\/\/blogs.bmj.com\/jmg\/files\/2016\/01\/Untitled-300x250.jpg\" alt=\"Untitled\" width=\"300\" height=\"250\" srcset=\"https:\/\/blogs.bmj.com\/jmg\/files\/2016\/01\/Untitled-300x250.jpg 300w, https:\/\/blogs.bmj.com\/jmg\/files\/2016\/01\/Untitled-768x641.jpg 768w, https:\/\/blogs.bmj.com\/jmg\/files\/2016\/01\/Untitled.jpg 933w\" sizes=\"auto, (max-width: 300px) 100vw, 300px\" \/><\/a><!--TrendMD v2.4.8--><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Wolf-Hirschhorn syndrome (WHS) is a contiguous gene deletion syndrome involving variable size deletions of the short arm of chromosome 4. Approximately 90% of individuals with WHS have seizures. These seizures can be intractable and can seriously affect an individual\u2019s quality of life, especially during childhood. &nbsp; To study the genetic correlates of seizure susceptibility in [&#8230;]<\/p>\n<p><a class=\"btn btn-secondary understrap-read-more-link\" href=\"https:\/\/blogs.bmj.com\/jmg\/2016\/01\/08\/a-genetic-region-associated-with-seizure-susceptibility-is-identified-in-wolf-hischhorn-syndrome\/\">Read More&#8230;<\/a><\/p>\n","protected":false},"author":123,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":["post-851","post","type-post","status-publish","format-standard","hentry","category-uncategorized"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.6 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>A Genetic Region Associated with Seizure Susceptibility is Identified in Wolf-Hischhorn Syndrome (Contributed by Dr. Karen Ho, Dr. John Carey, and Dr. Agatino Battaglia) - JMG Contact blog<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/blogs.bmj.com\/jmg\/2016\/01\/08\/a-genetic-region-associated-with-seizure-susceptibility-is-identified-in-wolf-hischhorn-syndrome\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"A Genetic Region Associated with Seizure Susceptibility is Identified in Wolf-Hischhorn Syndrome (Contributed by Dr. Karen Ho, Dr. John Carey, and Dr. Agatino Battaglia) - JMG Contact blog\" \/>\n<meta property=\"og:description\" content=\"Wolf-Hirschhorn syndrome (WHS) is a contiguous gene deletion syndrome involving variable size deletions of the short arm of chromosome 4. Approximately 90% of individuals with WHS have seizures. These seizures can be intractable and can seriously affect an individual\u2019s quality of life, especially during childhood. &nbsp; To study the genetic correlates of seizure susceptibility in [...]Read More...\" \/>\n<meta property=\"og:url\" content=\"https:\/\/blogs.bmj.com\/jmg\/2016\/01\/08\/a-genetic-region-associated-with-seizure-susceptibility-is-identified-in-wolf-hischhorn-syndrome\/\" \/>\n<meta property=\"og:site_name\" content=\"JMG Contact blog\" \/>\n<meta property=\"article:published_time\" content=\"2016-01-08T19:26:51+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2026-02-25T00:18:58+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/blogs.bmj.com\/jmg\/files\/2016\/01\/Untitled.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"933\" \/>\n\t<meta property=\"og:image:height\" content=\"779\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"hqqu\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:creator\" content=\"@HuiQiQu\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"hqqu\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/blogs.bmj.com\\\/jmg\\\/2016\\\/01\\\/08\\\/a-genetic-region-associated-with-seizure-susceptibility-is-identified-in-wolf-hischhorn-syndrome\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/blogs.bmj.com\\\/jmg\\\/2016\\\/01\\\/08\\\/a-genetic-region-associated-with-seizure-susceptibility-is-identified-in-wolf-hischhorn-syndrome\\\/\"},\"author\":{\"name\":\"hqqu\",\"@id\":\"https:\\\/\\\/blogs.bmj.com\\\/jmg\\\/#\\\/schema\\\/person\\\/be0250f8d5b52412c3e7c222dabd591b\"},\"headline\":\"A Genetic Region Associated with Seizure Susceptibility is Identified in Wolf-Hischhorn Syndrome (Contributed by Dr. Karen Ho, Dr. John Carey, and Dr. Agatino Battaglia)\",\"datePublished\":\"2016-01-08T19:26:51+00:00\",\"dateModified\":\"2026-02-25T00:18:58+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/blogs.bmj.com\\\/jmg\\\/2016\\\/01\\\/08\\\/a-genetic-region-associated-with-seizure-susceptibility-is-identified-in-wolf-hischhorn-syndrome\\\/\"},\"wordCount\":208,\"commentCount\":0,\"publisher\":{\"@id\":\"https:\\\/\\\/blogs.bmj.com\\\/jmg\\\/#organization\"},\"image\":{\"@id\":\"https:\\\/\\\/blogs.bmj.com\\\/jmg\\\/2016\\\/01\\\/08\\\/a-genetic-region-associated-with-seizure-susceptibility-is-identified-in-wolf-hischhorn-syndrome\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/blogs.bmj.com\\\/jmg\\\/files\\\/2016\\\/01\\\/Untitled-300x250.jpg\",\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"CommentAction\",\"name\":\"Comment\",\"target\":[\"https:\\\/\\\/blogs.bmj.com\\\/jmg\\\/2016\\\/01\\\/08\\\/a-genetic-region-associated-with-seizure-susceptibility-is-identified-in-wolf-hischhorn-syndrome\\\/#respond\"]}]},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/blogs.bmj.com\\\/jmg\\\/2016\\\/01\\\/08\\\/a-genetic-region-associated-with-seizure-susceptibility-is-identified-in-wolf-hischhorn-syndrome\\\/\",\"url\":\"https:\\\/\\\/blogs.bmj.com\\\/jmg\\\/2016\\\/01\\\/08\\\/a-genetic-region-associated-with-seizure-susceptibility-is-identified-in-wolf-hischhorn-syndrome\\\/\",\"name\":\"A Genetic Region Associated with Seizure Susceptibility is Identified in Wolf-Hischhorn Syndrome (Contributed by Dr. Karen Ho, Dr. John Carey, and Dr. Agatino Battaglia) - JMG Contact blog\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/blogs.bmj.com\\\/jmg\\\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\\\/\\\/blogs.bmj.com\\\/jmg\\\/2016\\\/01\\\/08\\\/a-genetic-region-associated-with-seizure-susceptibility-is-identified-in-wolf-hischhorn-syndrome\\\/#primaryimage\"},\"image\":{\"@id\":\"https:\\\/\\\/blogs.bmj.com\\\/jmg\\\/2016\\\/01\\\/08\\\/a-genetic-region-associated-with-seizure-susceptibility-is-identified-in-wolf-hischhorn-syndrome\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/blogs.bmj.com\\\/jmg\\\/files\\\/2016\\\/01\\\/Untitled-300x250.jpg\",\"datePublished\":\"2016-01-08T19:26:51+00:00\",\"dateModified\":\"2026-02-25T00:18:58+00:00\",\"breadcrumb\":{\"@id\":\"https:\\\/\\\/blogs.bmj.com\\\/jmg\\\/2016\\\/01\\\/08\\\/a-genetic-region-associated-with-seizure-susceptibility-is-identified-in-wolf-hischhorn-syndrome\\\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\\\/\\\/blogs.bmj.com\\\/jmg\\\/2016\\\/01\\\/08\\\/a-genetic-region-associated-with-seizure-susceptibility-is-identified-in-wolf-hischhorn-syndrome\\\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\\\/\\\/blogs.bmj.com\\\/jmg\\\/2016\\\/01\\\/08\\\/a-genetic-region-associated-with-seizure-susceptibility-is-identified-in-wolf-hischhorn-syndrome\\\/#primaryimage\",\"url\":\"https:\\\/\\\/blogs.bmj.com\\\/jmg\\\/files\\\/2016\\\/01\\\/Untitled.jpg\",\"contentUrl\":\"https:\\\/\\\/blogs.bmj.com\\\/jmg\\\/files\\\/2016\\\/01\\\/Untitled.jpg\",\"width\":933,\"height\":779},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\\\/\\\/blogs.bmj.com\\\/jmg\\\/2016\\\/01\\\/08\\\/a-genetic-region-associated-with-seizure-susceptibility-is-identified-in-wolf-hischhorn-syndrome\\\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\\\/\\\/blogs.bmj.com\\\/jmg\\\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"A Genetic Region Associated with Seizure Susceptibility is Identified in Wolf-Hischhorn Syndrome (Contributed by Dr. Karen Ho, Dr. John Carey, and Dr. Agatino Battaglia)\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\\\/\\\/blogs.bmj.com\\\/jmg\\\/#website\",\"url\":\"https:\\\/\\\/blogs.bmj.com\\\/jmg\\\/\",\"name\":\"JMG Contact blog\",\"description\":\"JMG Contact blog\",\"publisher\":{\"@id\":\"https:\\\/\\\/blogs.bmj.com\\\/jmg\\\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\\\/\\\/blogs.bmj.com\\\/jmg\\\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"},{\"@type\":\"Organization\",\"@id\":\"https:\\\/\\\/blogs.bmj.com\\\/jmg\\\/#organization\",\"name\":\"JMG Contact blog\",\"url\":\"https:\\\/\\\/blogs.bmj.com\\\/jmg\\\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\\\/\\\/blogs.bmj.com\\\/jmg\\\/#\\\/schema\\\/logo\\\/image\\\/\",\"url\":\"https:\\\/\\\/blogs.bmj.com\\\/jmg\\\/files\\\/2017\\\/10\\\/blog-logo-jmg.png\",\"contentUrl\":\"https:\\\/\\\/blogs.bmj.com\\\/jmg\\\/files\\\/2017\\\/10\\\/blog-logo-jmg.png\",\"width\":300,\"height\":34,\"caption\":\"JMG Contact blog\"},\"image\":{\"@id\":\"https:\\\/\\\/blogs.bmj.com\\\/jmg\\\/#\\\/schema\\\/logo\\\/image\\\/\"}},{\"@type\":\"Person\",\"@id\":\"https:\\\/\\\/blogs.bmj.com\\\/jmg\\\/#\\\/schema\\\/person\\\/be0250f8d5b52412c3e7c222dabd591b\",\"name\":\"hqqu\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/920bc4e81500cde88def4bfd7775029cb154e422c5460b9cf80d5c47137d6f35?s=96&d=mm&r=g\",\"url\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/920bc4e81500cde88def4bfd7775029cb154e422c5460b9cf80d5c47137d6f35?s=96&d=mm&r=g\",\"contentUrl\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/920bc4e81500cde88def4bfd7775029cb154e422c5460b9cf80d5c47137d6f35?s=96&d=mm&r=g\",\"caption\":\"hqqu\"},\"description\":\"Huiqi Qu has a background as a physician trained in internal medicine and a PhD in Experimental Medicine (Endocrinology). His research applies human genetics and multi-omics to complex and pediatric diseases, including GWAS, polygenic risk scores (PRS), single-cell transcriptomics, and integrative genomics to support precision medicine and clinical translation.\",\"sameAs\":[\"https:\\\/\\\/x.com\\\/HuiQiQu\"],\"url\":\"https:\\\/\\\/blogs.bmj.com\\\/jmg\\\/author\\\/hqiqu\\\/\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"A Genetic Region Associated with Seizure Susceptibility is Identified in Wolf-Hischhorn Syndrome (Contributed by Dr. Karen Ho, Dr. John Carey, and Dr. Agatino Battaglia) - JMG Contact blog","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/blogs.bmj.com\/jmg\/2016\/01\/08\/a-genetic-region-associated-with-seizure-susceptibility-is-identified-in-wolf-hischhorn-syndrome\/","og_locale":"en_US","og_type":"article","og_title":"A Genetic Region Associated with Seizure Susceptibility is Identified in Wolf-Hischhorn Syndrome (Contributed by Dr. Karen Ho, Dr. John Carey, and Dr. Agatino Battaglia) - JMG Contact blog","og_description":"Wolf-Hirschhorn syndrome (WHS) is a contiguous gene deletion syndrome involving variable size deletions of the short arm of chromosome 4. Approximately 90% of individuals with WHS have seizures. These seizures can be intractable and can seriously affect an individual\u2019s quality of life, especially during childhood. &nbsp; To study the genetic correlates of seizure susceptibility in [...]Read More...","og_url":"https:\/\/blogs.bmj.com\/jmg\/2016\/01\/08\/a-genetic-region-associated-with-seizure-susceptibility-is-identified-in-wolf-hischhorn-syndrome\/","og_site_name":"JMG Contact blog","article_published_time":"2016-01-08T19:26:51+00:00","article_modified_time":"2026-02-25T00:18:58+00:00","og_image":[{"width":933,"height":779,"url":"https:\/\/blogs.bmj.com\/jmg\/files\/2016\/01\/Untitled.jpg","type":"image\/jpeg"}],"author":"hqqu","twitter_card":"summary_large_image","twitter_creator":"@HuiQiQu","twitter_misc":{"Written by":"hqqu","Est. reading time":"1 minute"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/blogs.bmj.com\/jmg\/2016\/01\/08\/a-genetic-region-associated-with-seizure-susceptibility-is-identified-in-wolf-hischhorn-syndrome\/#article","isPartOf":{"@id":"https:\/\/blogs.bmj.com\/jmg\/2016\/01\/08\/a-genetic-region-associated-with-seizure-susceptibility-is-identified-in-wolf-hischhorn-syndrome\/"},"author":{"name":"hqqu","@id":"https:\/\/blogs.bmj.com\/jmg\/#\/schema\/person\/be0250f8d5b52412c3e7c222dabd591b"},"headline":"A Genetic Region Associated with Seizure Susceptibility is Identified in Wolf-Hischhorn Syndrome (Contributed by Dr. Karen Ho, Dr. John Carey, and Dr. Agatino Battaglia)","datePublished":"2016-01-08T19:26:51+00:00","dateModified":"2026-02-25T00:18:58+00:00","mainEntityOfPage":{"@id":"https:\/\/blogs.bmj.com\/jmg\/2016\/01\/08\/a-genetic-region-associated-with-seizure-susceptibility-is-identified-in-wolf-hischhorn-syndrome\/"},"wordCount":208,"commentCount":0,"publisher":{"@id":"https:\/\/blogs.bmj.com\/jmg\/#organization"},"image":{"@id":"https:\/\/blogs.bmj.com\/jmg\/2016\/01\/08\/a-genetic-region-associated-with-seizure-susceptibility-is-identified-in-wolf-hischhorn-syndrome\/#primaryimage"},"thumbnailUrl":"https:\/\/blogs.bmj.com\/jmg\/files\/2016\/01\/Untitled-300x250.jpg","inLanguage":"en-US","potentialAction":[{"@type":"CommentAction","name":"Comment","target":["https:\/\/blogs.bmj.com\/jmg\/2016\/01\/08\/a-genetic-region-associated-with-seizure-susceptibility-is-identified-in-wolf-hischhorn-syndrome\/#respond"]}]},{"@type":"WebPage","@id":"https:\/\/blogs.bmj.com\/jmg\/2016\/01\/08\/a-genetic-region-associated-with-seizure-susceptibility-is-identified-in-wolf-hischhorn-syndrome\/","url":"https:\/\/blogs.bmj.com\/jmg\/2016\/01\/08\/a-genetic-region-associated-with-seizure-susceptibility-is-identified-in-wolf-hischhorn-syndrome\/","name":"A Genetic Region Associated with Seizure Susceptibility is Identified in Wolf-Hischhorn Syndrome (Contributed by Dr. Karen Ho, Dr. John Carey, and Dr. Agatino Battaglia) - JMG Contact blog","isPartOf":{"@id":"https:\/\/blogs.bmj.com\/jmg\/#website"},"primaryImageOfPage":{"@id":"https:\/\/blogs.bmj.com\/jmg\/2016\/01\/08\/a-genetic-region-associated-with-seizure-susceptibility-is-identified-in-wolf-hischhorn-syndrome\/#primaryimage"},"image":{"@id":"https:\/\/blogs.bmj.com\/jmg\/2016\/01\/08\/a-genetic-region-associated-with-seizure-susceptibility-is-identified-in-wolf-hischhorn-syndrome\/#primaryimage"},"thumbnailUrl":"https:\/\/blogs.bmj.com\/jmg\/files\/2016\/01\/Untitled-300x250.jpg","datePublished":"2016-01-08T19:26:51+00:00","dateModified":"2026-02-25T00:18:58+00:00","breadcrumb":{"@id":"https:\/\/blogs.bmj.com\/jmg\/2016\/01\/08\/a-genetic-region-associated-with-seizure-susceptibility-is-identified-in-wolf-hischhorn-syndrome\/#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/blogs.bmj.com\/jmg\/2016\/01\/08\/a-genetic-region-associated-with-seizure-susceptibility-is-identified-in-wolf-hischhorn-syndrome\/"]}]},{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/blogs.bmj.com\/jmg\/2016\/01\/08\/a-genetic-region-associated-with-seizure-susceptibility-is-identified-in-wolf-hischhorn-syndrome\/#primaryimage","url":"https:\/\/blogs.bmj.com\/jmg\/files\/2016\/01\/Untitled.jpg","contentUrl":"https:\/\/blogs.bmj.com\/jmg\/files\/2016\/01\/Untitled.jpg","width":933,"height":779},{"@type":"BreadcrumbList","@id":"https:\/\/blogs.bmj.com\/jmg\/2016\/01\/08\/a-genetic-region-associated-with-seizure-susceptibility-is-identified-in-wolf-hischhorn-syndrome\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/blogs.bmj.com\/jmg\/"},{"@type":"ListItem","position":2,"name":"A Genetic Region Associated with Seizure Susceptibility is Identified in Wolf-Hischhorn Syndrome (Contributed by Dr. Karen Ho, Dr. John Carey, and Dr. Agatino Battaglia)"}]},{"@type":"WebSite","@id":"https:\/\/blogs.bmj.com\/jmg\/#website","url":"https:\/\/blogs.bmj.com\/jmg\/","name":"JMG Contact blog","description":"JMG Contact blog","publisher":{"@id":"https:\/\/blogs.bmj.com\/jmg\/#organization"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/blogs.bmj.com\/jmg\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"en-US"},{"@type":"Organization","@id":"https:\/\/blogs.bmj.com\/jmg\/#organization","name":"JMG Contact blog","url":"https:\/\/blogs.bmj.com\/jmg\/","logo":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/blogs.bmj.com\/jmg\/#\/schema\/logo\/image\/","url":"https:\/\/blogs.bmj.com\/jmg\/files\/2017\/10\/blog-logo-jmg.png","contentUrl":"https:\/\/blogs.bmj.com\/jmg\/files\/2017\/10\/blog-logo-jmg.png","width":300,"height":34,"caption":"JMG Contact blog"},"image":{"@id":"https:\/\/blogs.bmj.com\/jmg\/#\/schema\/logo\/image\/"}},{"@type":"Person","@id":"https:\/\/blogs.bmj.com\/jmg\/#\/schema\/person\/be0250f8d5b52412c3e7c222dabd591b","name":"hqqu","image":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/secure.gravatar.com\/avatar\/920bc4e81500cde88def4bfd7775029cb154e422c5460b9cf80d5c47137d6f35?s=96&d=mm&r=g","url":"https:\/\/secure.gravatar.com\/avatar\/920bc4e81500cde88def4bfd7775029cb154e422c5460b9cf80d5c47137d6f35?s=96&d=mm&r=g","contentUrl":"https:\/\/secure.gravatar.com\/avatar\/920bc4e81500cde88def4bfd7775029cb154e422c5460b9cf80d5c47137d6f35?s=96&d=mm&r=g","caption":"hqqu"},"description":"Huiqi Qu has a background as a physician trained in internal medicine and a PhD in Experimental Medicine (Endocrinology). His research applies human genetics and multi-omics to complex and pediatric diseases, including GWAS, polygenic risk scores (PRS), single-cell transcriptomics, and integrative genomics to support precision medicine and clinical translation.","sameAs":["https:\/\/x.com\/HuiQiQu"],"url":"https:\/\/blogs.bmj.com\/jmg\/author\/hqiqu\/"}]}},"_links":{"self":[{"href":"https:\/\/blogs.bmj.com\/jmg\/wp-json\/wp\/v2\/posts\/851","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/blogs.bmj.com\/jmg\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/blogs.bmj.com\/jmg\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/blogs.bmj.com\/jmg\/wp-json\/wp\/v2\/users\/123"}],"replies":[{"embeddable":true,"href":"https:\/\/blogs.bmj.com\/jmg\/wp-json\/wp\/v2\/comments?post=851"}],"version-history":[{"count":0,"href":"https:\/\/blogs.bmj.com\/jmg\/wp-json\/wp\/v2\/posts\/851\/revisions"}],"wp:attachment":[{"href":"https:\/\/blogs.bmj.com\/jmg\/wp-json\/wp\/v2\/media?parent=851"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/blogs.bmj.com\/jmg\/wp-json\/wp\/v2\/categories?post=851"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/blogs.bmj.com\/jmg\/wp-json\/wp\/v2\/tags?post=851"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}