{"id":642,"date":"2014-03-24T18:55:02","date_gmt":"2014-03-24T18:55:02","guid":{"rendered":"https:\/\/blogs.bmj.com\/jmg\/?p=642"},"modified":"2026-02-25T19:49:26","modified_gmt":"2026-02-25T19:49:26","slug":"mapping-of-hepatic-expression-quantitative-trait-loci-eqtls-in-a-han-chinese-population","status":"publish","type":"post","link":"https:\/\/blogs.bmj.com\/jmg\/2014\/03\/24\/mapping-of-hepatic-expression-quantitative-trait-loci-eqtls-in-a-han-chinese-population\/","title":{"rendered":"Mapping of hepatic expression quantitative trait loci (eQTLs) in a Han Chinese population (Contributed by Dr. Zhihai Peng)"},"content":{"rendered":"<p>Understanding genetic control for gene expression in human livers is important to elucidate the mechanism underlying health and disease. Wang et al. carried out the first genome-wide analysis in liver tissues of a Han Chinese population and observed 1,669 genetic loci significantly associated with hepatic gene expression. The study also found that at least 41% of these alleles were significantly associated hepatic gene expression in a Caucasian population. In addition, the study revealed that disease-associated alleles and the alleles significantly involved in drug metabolism and response were more likely to control gene expression in human livers. (<a href=\"http:\/\/jmg.bmj.com\/content\/early\/2014\/03\/24\/jmedgenet-2013-102045\">http:\/\/jmg.bmj.com\/content\/early\/2014\/03\/24\/jmedgenet-2013-102045<\/a> )<!--TrendMD v2.4.8--><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Understanding genetic control for gene expression in human livers is important to elucidate the mechanism underlying health and disease. Wang et al. carried out the first genome-wide analysis in liver tissues of a Han Chinese population and observed 1,669 genetic loci significantly associated with hepatic gene expression. The study also found that at least 41% [&#8230;]<\/p>\n<p><a class=\"btn btn-secondary understrap-read-more-link\" href=\"https:\/\/blogs.bmj.com\/jmg\/2014\/03\/24\/mapping-of-hepatic-expression-quantitative-trait-loci-eqtls-in-a-han-chinese-population\/\">Read More&#8230;<\/a><\/p>\n","protected":false},"author":123,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":["post-642","post","type-post","status-publish","format-standard","hentry","category-uncategorized"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.6 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Mapping of hepatic expression quantitative trait loci (eQTLs) in a Han Chinese population (Contributed by Dr. Zhihai Peng) - JMG Contact blog<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/blogs.bmj.com\/jmg\/2014\/03\/24\/mapping-of-hepatic-expression-quantitative-trait-loci-eqtls-in-a-han-chinese-population\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Mapping of hepatic expression quantitative trait loci (eQTLs) in a Han Chinese population (Contributed by Dr. Zhihai Peng) - JMG Contact blog\" \/>\n<meta property=\"og:description\" content=\"Understanding genetic control for gene expression in human livers is important to elucidate the mechanism underlying health and disease. Wang et al. carried out the first genome-wide analysis in liver tissues of a Han Chinese population and observed 1,669 genetic loci significantly associated with hepatic gene expression. The study also found that at least 41% [...]Read More...\" \/>\n<meta property=\"og:url\" content=\"https:\/\/blogs.bmj.com\/jmg\/2014\/03\/24\/mapping-of-hepatic-expression-quantitative-trait-loci-eqtls-in-a-han-chinese-population\/\" \/>\n<meta property=\"og:site_name\" content=\"JMG Contact blog\" \/>\n<meta property=\"article:published_time\" content=\"2014-03-24T18:55:02+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2026-02-25T19:49:26+00:00\" \/>\n<meta name=\"author\" content=\"hqqu\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:creator\" content=\"@HuiQiQu\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"hqqu\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/blogs.bmj.com\\\/jmg\\\/2014\\\/03\\\/24\\\/mapping-of-hepatic-expression-quantitative-trait-loci-eqtls-in-a-han-chinese-population\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/blogs.bmj.com\\\/jmg\\\/2014\\\/03\\\/24\\\/mapping-of-hepatic-expression-quantitative-trait-loci-eqtls-in-a-han-chinese-population\\\/\"},\"author\":{\"name\":\"hqqu\",\"@id\":\"https:\\\/\\\/blogs.bmj.com\\\/jmg\\\/#\\\/schema\\\/person\\\/be0250f8d5b52412c3e7c222dabd591b\"},\"headline\":\"Mapping of hepatic expression quantitative trait loci (eQTLs) in a Han Chinese population (Contributed by Dr. Zhihai Peng)\",\"datePublished\":\"2014-03-24T18:55:02+00:00\",\"dateModified\":\"2026-02-25T19:49:26+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/blogs.bmj.com\\\/jmg\\\/2014\\\/03\\\/24\\\/mapping-of-hepatic-expression-quantitative-trait-loci-eqtls-in-a-han-chinese-population\\\/\"},\"wordCount\":120,\"commentCount\":0,\"publisher\":{\"@id\":\"https:\\\/\\\/blogs.bmj.com\\\/jmg\\\/#organization\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"CommentAction\",\"name\":\"Comment\",\"target\":[\"https:\\\/\\\/blogs.bmj.com\\\/jmg\\\/2014\\\/03\\\/24\\\/mapping-of-hepatic-expression-quantitative-trait-loci-eqtls-in-a-han-chinese-population\\\/#respond\"]}]},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/blogs.bmj.com\\\/jmg\\\/2014\\\/03\\\/24\\\/mapping-of-hepatic-expression-quantitative-trait-loci-eqtls-in-a-han-chinese-population\\\/\",\"url\":\"https:\\\/\\\/blogs.bmj.com\\\/jmg\\\/2014\\\/03\\\/24\\\/mapping-of-hepatic-expression-quantitative-trait-loci-eqtls-in-a-han-chinese-population\\\/\",\"name\":\"Mapping of hepatic expression quantitative trait loci (eQTLs) in a Han Chinese population (Contributed by Dr. Zhihai Peng) - 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