{"id":373,"date":"2012-10-02T18:35:02","date_gmt":"2012-10-02T18:35:02","guid":{"rendered":"https:\/\/blogs.bmj.com\/jmg\/?p=373"},"modified":"2026-02-25T20:31:20","modified_gmt":"2026-02-25T20:31:20","slug":"the-speech-gene-foxp2-is-not-imprinted","status":"publish","type":"post","link":"https:\/\/blogs.bmj.com\/jmg\/2012\/10\/02\/the-speech-gene-foxp2-is-not-imprinted\/","title":{"rendered":"The speech gene FOXP2 is not imprinted (Contributed by Dr. Philip Stanier)"},"content":{"rendered":"<p><em>FOXP2<\/em> is a gene that plays a critical role in setting up the brain circuitry enabling\u00a0\u00a0 speech-language. \u00a0Preliminary data suggested that <em>FOXP2<\/em> could be regulated according to its parental origin (genomic imprinting), with only the paternal copy expressed. \u00a0Imprinting is thought to involve antagonism between the parental genomes and has been put forward as a theory to explain the evolution of speech and language. We tested the hypothesis that <em>FOXP2<\/em> is imprinted and found that this gene is expressed equally from both parental copies.\u00a0 We therefore conclude that parental conflict is an unlikely evolutionary mechanism for speech and language function.\u00a0 (<a href=\"http:\/\/jmg.bmj.com\/content\/early\/2012\/10\/01\/jmedgenet-2012-101242\">http:\/\/jmg.bmj.com\/content\/early\/2012\/10\/01\/jmedgenet-2012-101242<\/a> )<!--TrendMD v2.4.8--><\/p>\n","protected":false},"excerpt":{"rendered":"<p>FOXP2 is a gene that plays a critical role in setting up the brain circuitry enabling\u00a0\u00a0 speech-language. \u00a0Preliminary data suggested that FOXP2 could be regulated according to its parental origin (genomic imprinting), with only the paternal copy expressed. \u00a0Imprinting is thought to involve antagonism between the parental genomes and has been put forward as a [&#8230;]<\/p>\n<p><a class=\"btn btn-secondary understrap-read-more-link\" href=\"https:\/\/blogs.bmj.com\/jmg\/2012\/10\/02\/the-speech-gene-foxp2-is-not-imprinted\/\">Read More&#8230;<\/a><\/p>\n","protected":false},"author":123,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":["post-373","post","type-post","status-publish","format-standard","hentry","category-uncategorized"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.4 - 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