{"id":2235,"date":"2026-09-23T14:27:19","date_gmt":"2026-09-23T14:27:19","guid":{"rendered":"https:\/\/blogs.bmj.com\/jmg\/?p=2235"},"modified":"2026-09-23T14:27:19","modified_gmt":"2026-09-23T14:27:19","slug":"review-of-estimates-of-birth-incidence-and-population-prevalence-over-time-and-between-countries-of-the-rare-neurodevelopmental-condition-prader-willi-syndrome-contributed-by-dr-joyce-whittington","status":"publish","type":"post","link":"https:\/\/blogs.bmj.com\/jmg\/2026\/09\/23\/review-of-estimates-of-birth-incidence-and-population-prevalence-over-time-and-between-countries-of-the-rare-neurodevelopmental-condition-prader-willi-syndrome-contributed-by-dr-joyce-whittington\/","title":{"rendered":"Review of estimates of birth incidence and population prevalence over time and between countries of the rare neurodevelopmental condition Prader-Willi syndrome (Contributed by Dr Joyce Whittington)"},"content":{"rendered":"<p>The aims of the study were to answer the questions: are there universal values for birth incidence and population prevalence for the rare neurodevelopmental condition Prader-Willi syndrome (PWS)? If so, why are published estimates so widely different? A review of the 11 published estimates revealed methodological flaws resulting in higher estimates. Consideration of characteristics of PWS and the use of appropriate methods showed that any accurate estimate would depend on the demographics of the population at that point in time. In the absence of studies of the effects of characteristics, such as ethnicity, on prevalence rates, it is not known whether other factors also influence incidence and prevalence rates. (<a href=\"https:\/\/jmg.bmj.com\/content\/63\/9\/543\">https:\/\/jmg.bmj.com\/content\/63\/9\/543<\/a>)<!--TrendMD v2.4.8--><\/p>\n","protected":false},"excerpt":{"rendered":"<p>The aims of the study were to answer the questions: are there universal values for birth incidence and population prevalence for the rare neurodevelopmental condition Prader-Willi syndrome (PWS)? If so, why are published estimates so widely different? A review of the 11 published estimates revealed methodological flaws resulting in higher estimates. Consideration of characteristics of [&#8230;]<\/p>\n<p><a class=\"btn btn-secondary understrap-read-more-link\" href=\"https:\/\/blogs.bmj.com\/jmg\/2026\/09\/23\/review-of-estimates-of-birth-incidence-and-population-prevalence-over-time-and-between-countries-of-the-rare-neurodevelopmental-condition-prader-willi-syndrome-contributed-by-dr-joyce-whittington\/\">Read More&#8230;<\/a><\/p>\n","protected":false},"author":123,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":["post-2235","post","type-post","status-publish","format-standard","hentry","category-uncategorized"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.7 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Review of estimates of birth incidence and population prevalence over time and between countries of the rare neurodevelopmental condition Prader-Willi syndrome (Contributed by Dr Joyce Whittington) - JMG Contact blog<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/blogs.bmj.com\/jmg\/2026\/09\/23\/review-of-estimates-of-birth-incidence-and-population-prevalence-over-time-and-between-countries-of-the-rare-neurodevelopmental-condition-prader-willi-syndrome-contributed-by-dr-joyce-whittington\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Review of estimates of birth incidence and population prevalence over time and between countries of the rare neurodevelopmental condition Prader-Willi syndrome (Contributed by Dr Joyce Whittington) - JMG Contact blog\" \/>\n<meta property=\"og:description\" content=\"The aims of the study were to answer the questions: are there universal values for birth incidence and population prevalence for the rare neurodevelopmental condition Prader-Willi syndrome (PWS)? If so, why are published estimates so widely different? A review of the 11 published estimates revealed methodological flaws resulting in higher estimates. Consideration of characteristics of [...]Read More...\" \/>\n<meta property=\"og:url\" content=\"https:\/\/blogs.bmj.com\/jmg\/2026\/09\/23\/review-of-estimates-of-birth-incidence-and-population-prevalence-over-time-and-between-countries-of-the-rare-neurodevelopmental-condition-prader-willi-syndrome-contributed-by-dr-joyce-whittington\/\" \/>\n<meta property=\"og:site_name\" content=\"JMG Contact blog\" \/>\n<meta property=\"article:published_time\" content=\"2026-09-23T14:27:19+00:00\" \/>\n<meta name=\"author\" content=\"hqqu\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:creator\" content=\"@HuiQiQu\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"hqqu\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/blogs.bmj.com\\\/jmg\\\/2026\\\/09\\\/23\\\/review-of-estimates-of-birth-incidence-and-population-prevalence-over-time-and-between-countries-of-the-rare-neurodevelopmental-condition-prader-willi-syndrome-contributed-by-dr-joyce-whittington\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/blogs.bmj.com\\\/jmg\\\/2026\\\/09\\\/23\\\/review-of-estimates-of-birth-incidence-and-population-prevalence-over-time-and-between-countries-of-the-rare-neurodevelopmental-condition-prader-willi-syndrome-contributed-by-dr-joyce-whittington\\\/\"},\"author\":{\"name\":\"hqqu\",\"@id\":\"https:\\\/\\\/blogs.bmj.com\\\/jmg\\\/#\\\/schema\\\/person\\\/be0250f8d5b52412c3e7c222dabd591b\"},\"headline\":\"Review of estimates of birth incidence and population prevalence over time and between countries of the rare neurodevelopmental condition Prader-Willi syndrome (Contributed by Dr Joyce Whittington)\",\"datePublished\":\"2026-09-23T14:27:19+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/blogs.bmj.com\\\/jmg\\\/2026\\\/09\\\/23\\\/review-of-estimates-of-birth-incidence-and-population-prevalence-over-time-and-between-countries-of-the-rare-neurodevelopmental-condition-prader-willi-syndrome-contributed-by-dr-joyce-whittington\\\/\"},\"wordCount\":139,\"commentCount\":0,\"publisher\":{\"@id\":\"https:\\\/\\\/blogs.bmj.com\\\/jmg\\\/#organization\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"CommentAction\",\"name\":\"Comment\",\"target\":[\"https:\\\/\\\/blogs.bmj.com\\\/jmg\\\/2026\\\/09\\\/23\\\/review-of-estimates-of-birth-incidence-and-population-prevalence-over-time-and-between-countries-of-the-rare-neurodevelopmental-condition-prader-willi-syndrome-contributed-by-dr-joyce-whittington\\\/#respond\"]}]},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/blogs.bmj.com\\\/jmg\\\/2026\\\/09\\\/23\\\/review-of-estimates-of-birth-incidence-and-population-prevalence-over-time-and-between-countries-of-the-rare-neurodevelopmental-condition-prader-willi-syndrome-contributed-by-dr-joyce-whittington\\\/\",\"url\":\"https:\\\/\\\/blogs.bmj.com\\\/jmg\\\/2026\\\/09\\\/23\\\/review-of-estimates-of-birth-incidence-and-population-prevalence-over-time-and-between-countries-of-the-rare-neurodevelopmental-condition-prader-willi-syndrome-contributed-by-dr-joyce-whittington\\\/\",\"name\":\"Review of estimates of birth incidence and population prevalence over time and between countries of the rare neurodevelopmental condition Prader-Willi syndrome (Contributed by Dr Joyce Whittington) - 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