{"id":2232,"date":"2026-09-23T14:15:50","date_gmt":"2026-09-23T14:15:50","guid":{"rendered":"https:\/\/blogs.bmj.com\/jmg\/?p=2232"},"modified":"2026-09-23T14:15:50","modified_gmt":"2026-09-23T14:15:50","slug":"evaluating-consistency-and-variation-in-mainstream-germline-cancer-genetic-and-genomic-testing-contributed-by-dr-agnes-sebastian","status":"publish","type":"post","link":"https:\/\/blogs.bmj.com\/jmg\/2026\/09\/23\/evaluating-consistency-and-variation-in-mainstream-germline-cancer-genetic-and-genomic-testing-contributed-by-dr-agnes-sebastian\/","title":{"rendered":"Evaluating consistency and variation in mainstream germline cancer genetic and genomic testing (Contributed by Dr Agnes Sebastian)"},"content":{"rendered":"

Mainstreaming\u2014shifting genetic testing outside clinical genetics\u2014can improve access, but requires evaluation to ensure consistent, high-quality care. This study assessed real-world implementation of mainstream cancer genetic testing across multiple centres and cancer types, incorporating both clinical and laboratory genetics perspectives. Practice was broadly aligned for common indications, including breast, ovarian, and prostate cancer. However, variability remained in areas with implications for resource use and care quality, including routine result turnaround time, negative-result management, and the extent of genetics-service involvement. These findings highlight opportunities to optimize mainstreaming and support more consistent, equitable cancer genetics care. (https:\/\/jmg.bmj.com\/content\/early\/2026\/09\/21\/jmg-2026-111749<\/a>)<\/p>\n","protected":false},"excerpt":{"rendered":"

Mainstreaming\u2014shifting genetic testing outside clinical genetics\u2014can improve access, but requires evaluation to ensure consistent, high-quality care. This study assessed real-world implementation of mainstream cancer genetic testing across multiple centres and cancer types, incorporating both clinical and laboratory genetics perspectives. Practice was broadly aligned for common indications, including breast, ovarian, and prostate cancer. However, variability remained […]<\/p>\n

Read More…<\/a><\/p>\n","protected":false},"author":123,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":["post-2232","post","type-post","status-publish","format-standard","hentry","category-uncategorized"],"yoast_head":"\nEvaluating consistency and variation in mainstream germline cancer genetic and genomic testing (Contributed by Dr Agnes Sebastian) - JMG Contact blog<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/blogs.bmj.com\/jmg\/2026\/09\/23\/evaluating-consistency-and-variation-in-mainstream-germline-cancer-genetic-and-genomic-testing-contributed-by-dr-agnes-sebastian\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Evaluating consistency and variation in mainstream germline cancer genetic and genomic testing (Contributed by Dr Agnes Sebastian) - JMG Contact blog\" \/>\n<meta property=\"og:description\" content=\"Mainstreaming\u2014shifting genetic testing outside clinical genetics\u2014can improve access, but requires evaluation to ensure consistent, high-quality care. 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