{"id":2043,"date":"2025-01-21T14:28:15","date_gmt":"2025-01-21T14:28:15","guid":{"rendered":"https:\/\/blogs.bmj.com\/jmg\/?p=2043"},"modified":"2026-02-22T01:18:10","modified_gmt":"2026-02-22T01:18:10","slug":"under-recognized-neurocognitive-deficits-in-adults-and-adolescents-with-tuberous-sclerosis-complex","status":"publish","type":"post","link":"https:\/\/blogs.bmj.com\/jmg\/2025\/01\/21\/under-recognized-neurocognitive-deficits-in-adults-and-adolescents-with-tuberous-sclerosis-complex\/","title":{"rendered":"Under-recognized neurocognitive deficits in adults and adolescents with Tuberous Sclerosis Complex (Contributed by Dr Mark R Keezer)"},"content":{"rendered":"

Tuberous sclerosis complex (TSC) is a genetic disease that is often associated with cognitive deficits, including intellectual disability. Screening for these deficits can be done by asking a patient and their caregiver to complete the TAND Checklist. Our study compared the use of this checklist with screening neurocognitive tests such as the Symbol Digit Modalities Test. We recruited adults and adolescents with TSC and mild, moderate or no intellectual disability. We found that screening neurocognitive tests may be beneficial in detecting unrecognized neurocognitive deficits in people with TSC. These deficits may be related to a person\u2019s TSC but also their epilepsy and medications. (https:\/\/jmg.bmj.com\/content\/early\/2025\/01\/19\/jmg-2024-110388<\/a> )<\/p>\n

\"\"<\/a><\/p>\n

The authors M\u00e9lissa Boisclair and Laury-Anne Blondeau<\/p>\n","protected":false},"excerpt":{"rendered":"

Tuberous sclerosis complex (TSC) is a genetic disease that is often associated with cognitive deficits, including intellectual disability. Screening for these deficits can be done by asking a patient and their caregiver to complete the TAND Checklist. Our study compared the use of this checklist with screening neurocognitive tests such as the Symbol Digit Modalities […]<\/p>\n

Read More…<\/a><\/p>\n","protected":false},"author":123,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":["post-2043","post","type-post","status-publish","format-standard","hentry","category-uncategorized"],"yoast_head":"\nUnder-recognized neurocognitive deficits in adults and adolescents with Tuberous Sclerosis Complex (Contributed by Dr Mark R Keezer) - JMG Contact blog<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/blogs.bmj.com\/jmg\/2025\/01\/21\/under-recognized-neurocognitive-deficits-in-adults-and-adolescents-with-tuberous-sclerosis-complex\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Under-recognized neurocognitive deficits in adults and adolescents with Tuberous Sclerosis Complex (Contributed by Dr Mark R Keezer) - JMG Contact blog\" \/>\n<meta property=\"og:description\" content=\"Tuberous sclerosis complex (TSC) is a genetic disease that is often associated with cognitive deficits, including intellectual disability. Screening for these deficits can be done by asking a patient and their caregiver to complete the TAND Checklist. Our study compared the use of this checklist with screening neurocognitive tests such as the Symbol Digit Modalities [...]Read More...\" \/>\n<meta property=\"og:url\" content=\"https:\/\/blogs.bmj.com\/jmg\/2025\/01\/21\/under-recognized-neurocognitive-deficits-in-adults-and-adolescents-with-tuberous-sclerosis-complex\/\" \/>\n<meta property=\"og:site_name\" content=\"JMG Contact blog\" \/>\n<meta property=\"article:published_time\" content=\"2025-01-21T14:28:15+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2026-02-22T01:18:10+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/blogs.bmj.com\/jmg\/files\/2025\/01\/Presentation1.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"1280\" \/>\n\t<meta property=\"og:image:height\" content=\"720\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"hqqu\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:creator\" content=\"@HuiQiQu\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"hqqu\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/blogs.bmj.com\\\/jmg\\\/2025\\\/01\\\/21\\\/under-recognized-neurocognitive-deficits-in-adults-and-adolescents-with-tuberous-sclerosis-complex\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/blogs.bmj.com\\\/jmg\\\/2025\\\/01\\\/21\\\/under-recognized-neurocognitive-deficits-in-adults-and-adolescents-with-tuberous-sclerosis-complex\\\/\"},\"author\":{\"name\":\"hqqu\",\"@id\":\"https:\\\/\\\/blogs.bmj.com\\\/jmg\\\/#\\\/schema\\\/person\\\/be0250f8d5b52412c3e7c222dabd591b\"},\"headline\":\"Under-recognized neurocognitive deficits in adults and adolescents with Tuberous Sclerosis Complex (Contributed by Dr Mark R Keezer)\",\"datePublished\":\"2025-01-21T14:28:15+00:00\",\"dateModified\":\"2026-02-22T01:18:10+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/blogs.bmj.com\\\/jmg\\\/2025\\\/01\\\/21\\\/under-recognized-neurocognitive-deficits-in-adults-and-adolescents-with-tuberous-sclerosis-complex\\\/\"},\"wordCount\":137,\"commentCount\":0,\"publisher\":{\"@id\":\"https:\\\/\\\/blogs.bmj.com\\\/jmg\\\/#organization\"},\"image\":{\"@id\":\"https:\\\/\\\/blogs.bmj.com\\\/jmg\\\/2025\\\/01\\\/21\\\/under-recognized-neurocognitive-deficits-in-adults-and-adolescents-with-tuberous-sclerosis-complex\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/blogs.bmj.com\\\/jmg\\\/files\\\/2025\\\/01\\\/Presentation1-300x169.jpg\",\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"CommentAction\",\"name\":\"Comment\",\"target\":[\"https:\\\/\\\/blogs.bmj.com\\\/jmg\\\/2025\\\/01\\\/21\\\/under-recognized-neurocognitive-deficits-in-adults-and-adolescents-with-tuberous-sclerosis-complex\\\/#respond\"]}]},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/blogs.bmj.com\\\/jmg\\\/2025\\\/01\\\/21\\\/under-recognized-neurocognitive-deficits-in-adults-and-adolescents-with-tuberous-sclerosis-complex\\\/\",\"url\":\"https:\\\/\\\/blogs.bmj.com\\\/jmg\\\/2025\\\/01\\\/21\\\/under-recognized-neurocognitive-deficits-in-adults-and-adolescents-with-tuberous-sclerosis-complex\\\/\",\"name\":\"Under-recognized neurocognitive deficits in adults and adolescents with Tuberous Sclerosis Complex (Contributed by Dr Mark R Keezer) - 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