{"id":2040,"date":"2025-01-14T18:03:11","date_gmt":"2025-01-14T18:03:11","guid":{"rendered":"https:\/\/blogs.bmj.com\/jmg\/?p=2040"},"modified":"2026-02-22T01:19:32","modified_gmt":"2026-02-22T01:19:32","slug":"advances-in-research-on-the-mechanism-of-tsrna-action-in-tumours","status":"publish","type":"post","link":"https:\/\/blogs.bmj.com\/jmg\/2025\/01\/14\/advances-in-research-on-the-mechanism-of-tsrna-action-in-tumours\/","title":{"rendered":"Advances in research on the mechanism of tsRNA action in tumours (Contributed by Professor Ming Lei)"},"content":{"rendered":"<p>At present, many studies have emphasized the importance of tsRNAs in tumors and revealed their important role in the biological processes of tumor cell proliferation, apoptosis, and metastasis. By systematically analyzing the production and biological function of tsRNAs in various tumors, we elucidate its mechanism of action in tumor occurrence and progression, and discuss their potential as biomarkers and therapeutic targets, as well as their application prospects in tumor precision medicine. We believe our review can provide valuable insights and direction for innovation in cancer research and treatment strategies. (<a href=\"https:\/\/jmg.bmj.com\/content\/early\/2024\/12\/31\/jmg-2024-110437\">https:\/\/jmg.bmj.com\/content\/early\/2024\/12\/31\/jmg-2024-110437<\/a> )<!--TrendMD v2.4.8--><\/p>\n","protected":false},"excerpt":{"rendered":"<p>At present, many studies have emphasized the importance of tsRNAs in tumors and revealed their important role in the biological processes of tumor cell proliferation, apoptosis, and metastasis. By systematically analyzing the production and biological function of tsRNAs in various tumors, we elucidate its mechanism of action in tumor occurrence and progression, and discuss their [&#8230;]<\/p>\n<p><a class=\"btn btn-secondary understrap-read-more-link\" href=\"https:\/\/blogs.bmj.com\/jmg\/2025\/01\/14\/advances-in-research-on-the-mechanism-of-tsrna-action-in-tumours\/\">Read More&#8230;<\/a><\/p>\n","protected":false},"author":123,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":["post-2040","post","type-post","status-publish","format-standard","hentry","category-uncategorized"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.5 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Advances in research on the mechanism of tsRNA action in tumours (Contributed by Professor Ming Lei) - JMG Contact blog<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/blogs.bmj.com\/jmg\/2025\/01\/14\/advances-in-research-on-the-mechanism-of-tsrna-action-in-tumours\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Advances in research on the mechanism of tsRNA action in tumours (Contributed by Professor Ming Lei) - JMG Contact blog\" \/>\n<meta property=\"og:description\" content=\"At present, many studies have emphasized the importance of tsRNAs in tumors and revealed their important role in the biological processes of tumor cell proliferation, apoptosis, and metastasis. By systematically analyzing the production and biological function of tsRNAs in various tumors, we elucidate its mechanism of action in tumor occurrence and progression, and discuss their [...]Read More...\" \/>\n<meta property=\"og:url\" content=\"https:\/\/blogs.bmj.com\/jmg\/2025\/01\/14\/advances-in-research-on-the-mechanism-of-tsrna-action-in-tumours\/\" \/>\n<meta property=\"og:site_name\" content=\"JMG Contact blog\" \/>\n<meta property=\"article:published_time\" content=\"2025-01-14T18:03:11+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2026-02-22T01:19:32+00:00\" \/>\n<meta name=\"author\" content=\"hqqu\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:creator\" content=\"@HuiQiQu\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"hqqu\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/blogs.bmj.com\\\/jmg\\\/2025\\\/01\\\/14\\\/advances-in-research-on-the-mechanism-of-tsrna-action-in-tumours\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/blogs.bmj.com\\\/jmg\\\/2025\\\/01\\\/14\\\/advances-in-research-on-the-mechanism-of-tsrna-action-in-tumours\\\/\"},\"author\":{\"name\":\"hqqu\",\"@id\":\"https:\\\/\\\/blogs.bmj.com\\\/jmg\\\/#\\\/schema\\\/person\\\/be0250f8d5b52412c3e7c222dabd591b\"},\"headline\":\"Advances in research on the mechanism of tsRNA action in tumours (Contributed by Professor Ming Lei)\",\"datePublished\":\"2025-01-14T18:03:11+00:00\",\"dateModified\":\"2026-02-22T01:19:32+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/blogs.bmj.com\\\/jmg\\\/2025\\\/01\\\/14\\\/advances-in-research-on-the-mechanism-of-tsrna-action-in-tumours\\\/\"},\"wordCount\":113,\"commentCount\":0,\"publisher\":{\"@id\":\"https:\\\/\\\/blogs.bmj.com\\\/jmg\\\/#organization\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"CommentAction\",\"name\":\"Comment\",\"target\":[\"https:\\\/\\\/blogs.bmj.com\\\/jmg\\\/2025\\\/01\\\/14\\\/advances-in-research-on-the-mechanism-of-tsrna-action-in-tumours\\\/#respond\"]}]},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/blogs.bmj.com\\\/jmg\\\/2025\\\/01\\\/14\\\/advances-in-research-on-the-mechanism-of-tsrna-action-in-tumours\\\/\",\"url\":\"https:\\\/\\\/blogs.bmj.com\\\/jmg\\\/2025\\\/01\\\/14\\\/advances-in-research-on-the-mechanism-of-tsrna-action-in-tumours\\\/\",\"name\":\"Advances in research on the mechanism of tsRNA action in tumours (Contributed by Professor Ming Lei) - JMG Contact blog\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/blogs.bmj.com\\\/jmg\\\/#website\"},\"datePublished\":\"2025-01-14T18:03:11+00:00\",\"dateModified\":\"2026-02-22T01:19:32+00:00\",\"breadcrumb\":{\"@id\":\"https:\\\/\\\/blogs.bmj.com\\\/jmg\\\/2025\\\/01\\\/14\\\/advances-in-research-on-the-mechanism-of-tsrna-action-in-tumours\\\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\\\/\\\/blogs.bmj.com\\\/jmg\\\/2025\\\/01\\\/14\\\/advances-in-research-on-the-mechanism-of-tsrna-action-in-tumours\\\/\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\\\/\\\/blogs.bmj.com\\\/jmg\\\/2025\\\/01\\\/14\\\/advances-in-research-on-the-mechanism-of-tsrna-action-in-tumours\\\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\\\/\\\/blogs.bmj.com\\\/jmg\\\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Advances in research on the mechanism of tsRNA action in tumours (Contributed by Professor Ming Lei)\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\\\/\\\/blogs.bmj.com\\\/jmg\\\/#website\",\"url\":\"https:\\\/\\\/blogs.bmj.com\\\/jmg\\\/\",\"name\":\"JMG Contact blog\",\"description\":\"JMG Contact blog\",\"publisher\":{\"@id\":\"https:\\\/\\\/blogs.bmj.com\\\/jmg\\\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\\\/\\\/blogs.bmj.com\\\/jmg\\\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"},{\"@type\":\"Organization\",\"@id\":\"https:\\\/\\\/blogs.bmj.com\\\/jmg\\\/#organization\",\"name\":\"JMG Contact blog\",\"url\":\"https:\\\/\\\/blogs.bmj.com\\\/jmg\\\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\\\/\\\/blogs.bmj.com\\\/jmg\\\/#\\\/schema\\\/logo\\\/image\\\/\",\"url\":\"https:\\\/\\\/blogs.bmj.com\\\/jmg\\\/files\\\/2017\\\/10\\\/blog-logo-jmg.png\",\"contentUrl\":\"https:\\\/\\\/blogs.bmj.com\\\/jmg\\\/files\\\/2017\\\/10\\\/blog-logo-jmg.png\",\"width\":300,\"height\":34,\"caption\":\"JMG Contact blog\"},\"image\":{\"@id\":\"https:\\\/\\\/blogs.bmj.com\\\/jmg\\\/#\\\/schema\\\/logo\\\/image\\\/\"}},{\"@type\":\"Person\",\"@id\":\"https:\\\/\\\/blogs.bmj.com\\\/jmg\\\/#\\\/schema\\\/person\\\/be0250f8d5b52412c3e7c222dabd591b\",\"name\":\"hqqu\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/920bc4e81500cde88def4bfd7775029cb154e422c5460b9cf80d5c47137d6f35?s=96&d=mm&r=g\",\"url\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/920bc4e81500cde88def4bfd7775029cb154e422c5460b9cf80d5c47137d6f35?s=96&d=mm&r=g\",\"contentUrl\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/920bc4e81500cde88def4bfd7775029cb154e422c5460b9cf80d5c47137d6f35?s=96&d=mm&r=g\",\"caption\":\"hqqu\"},\"description\":\"Huiqi Qu has a background as a physician trained in internal medicine and a PhD in Experimental Medicine (Endocrinology). His research applies human genetics and multi-omics to complex and pediatric diseases, including GWAS, polygenic risk scores (PRS), single-cell transcriptomics, and integrative genomics to support precision medicine and clinical translation.\",\"sameAs\":[\"https:\\\/\\\/x.com\\\/HuiQiQu\"],\"url\":\"https:\\\/\\\/blogs.bmj.com\\\/jmg\\\/author\\\/hqiqu\\\/\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Advances in research on the mechanism of tsRNA action in tumours (Contributed by Professor Ming Lei) - JMG Contact blog","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/blogs.bmj.com\/jmg\/2025\/01\/14\/advances-in-research-on-the-mechanism-of-tsrna-action-in-tumours\/","og_locale":"en_US","og_type":"article","og_title":"Advances in research on the mechanism of tsRNA action in tumours (Contributed by Professor Ming Lei) - JMG Contact blog","og_description":"At present, many studies have emphasized the importance of tsRNAs in tumors and revealed their important role in the biological processes of tumor cell proliferation, apoptosis, and metastasis. By systematically analyzing the production and biological function of tsRNAs in various tumors, we elucidate its mechanism of action in tumor occurrence and progression, and discuss their [...]Read More...","og_url":"https:\/\/blogs.bmj.com\/jmg\/2025\/01\/14\/advances-in-research-on-the-mechanism-of-tsrna-action-in-tumours\/","og_site_name":"JMG Contact blog","article_published_time":"2025-01-14T18:03:11+00:00","article_modified_time":"2026-02-22T01:19:32+00:00","author":"hqqu","twitter_card":"summary_large_image","twitter_creator":"@HuiQiQu","twitter_misc":{"Written by":"hqqu","Est. reading time":"1 minute"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/blogs.bmj.com\/jmg\/2025\/01\/14\/advances-in-research-on-the-mechanism-of-tsrna-action-in-tumours\/#article","isPartOf":{"@id":"https:\/\/blogs.bmj.com\/jmg\/2025\/01\/14\/advances-in-research-on-the-mechanism-of-tsrna-action-in-tumours\/"},"author":{"name":"hqqu","@id":"https:\/\/blogs.bmj.com\/jmg\/#\/schema\/person\/be0250f8d5b52412c3e7c222dabd591b"},"headline":"Advances in research on the mechanism of tsRNA action in tumours (Contributed by Professor Ming Lei)","datePublished":"2025-01-14T18:03:11+00:00","dateModified":"2026-02-22T01:19:32+00:00","mainEntityOfPage":{"@id":"https:\/\/blogs.bmj.com\/jmg\/2025\/01\/14\/advances-in-research-on-the-mechanism-of-tsrna-action-in-tumours\/"},"wordCount":113,"commentCount":0,"publisher":{"@id":"https:\/\/blogs.bmj.com\/jmg\/#organization"},"inLanguage":"en-US","potentialAction":[{"@type":"CommentAction","name":"Comment","target":["https:\/\/blogs.bmj.com\/jmg\/2025\/01\/14\/advances-in-research-on-the-mechanism-of-tsrna-action-in-tumours\/#respond"]}]},{"@type":"WebPage","@id":"https:\/\/blogs.bmj.com\/jmg\/2025\/01\/14\/advances-in-research-on-the-mechanism-of-tsrna-action-in-tumours\/","url":"https:\/\/blogs.bmj.com\/jmg\/2025\/01\/14\/advances-in-research-on-the-mechanism-of-tsrna-action-in-tumours\/","name":"Advances in research on the mechanism of tsRNA action in tumours (Contributed by Professor Ming Lei) - JMG Contact blog","isPartOf":{"@id":"https:\/\/blogs.bmj.com\/jmg\/#website"},"datePublished":"2025-01-14T18:03:11+00:00","dateModified":"2026-02-22T01:19:32+00:00","breadcrumb":{"@id":"https:\/\/blogs.bmj.com\/jmg\/2025\/01\/14\/advances-in-research-on-the-mechanism-of-tsrna-action-in-tumours\/#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/blogs.bmj.com\/jmg\/2025\/01\/14\/advances-in-research-on-the-mechanism-of-tsrna-action-in-tumours\/"]}]},{"@type":"BreadcrumbList","@id":"https:\/\/blogs.bmj.com\/jmg\/2025\/01\/14\/advances-in-research-on-the-mechanism-of-tsrna-action-in-tumours\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/blogs.bmj.com\/jmg\/"},{"@type":"ListItem","position":2,"name":"Advances in research on the mechanism of tsRNA action in tumours (Contributed by Professor Ming Lei)"}]},{"@type":"WebSite","@id":"https:\/\/blogs.bmj.com\/jmg\/#website","url":"https:\/\/blogs.bmj.com\/jmg\/","name":"JMG Contact blog","description":"JMG Contact blog","publisher":{"@id":"https:\/\/blogs.bmj.com\/jmg\/#organization"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/blogs.bmj.com\/jmg\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"en-US"},{"@type":"Organization","@id":"https:\/\/blogs.bmj.com\/jmg\/#organization","name":"JMG Contact blog","url":"https:\/\/blogs.bmj.com\/jmg\/","logo":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/blogs.bmj.com\/jmg\/#\/schema\/logo\/image\/","url":"https:\/\/blogs.bmj.com\/jmg\/files\/2017\/10\/blog-logo-jmg.png","contentUrl":"https:\/\/blogs.bmj.com\/jmg\/files\/2017\/10\/blog-logo-jmg.png","width":300,"height":34,"caption":"JMG Contact blog"},"image":{"@id":"https:\/\/blogs.bmj.com\/jmg\/#\/schema\/logo\/image\/"}},{"@type":"Person","@id":"https:\/\/blogs.bmj.com\/jmg\/#\/schema\/person\/be0250f8d5b52412c3e7c222dabd591b","name":"hqqu","image":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/secure.gravatar.com\/avatar\/920bc4e81500cde88def4bfd7775029cb154e422c5460b9cf80d5c47137d6f35?s=96&d=mm&r=g","url":"https:\/\/secure.gravatar.com\/avatar\/920bc4e81500cde88def4bfd7775029cb154e422c5460b9cf80d5c47137d6f35?s=96&d=mm&r=g","contentUrl":"https:\/\/secure.gravatar.com\/avatar\/920bc4e81500cde88def4bfd7775029cb154e422c5460b9cf80d5c47137d6f35?s=96&d=mm&r=g","caption":"hqqu"},"description":"Huiqi Qu has a background as a physician trained in internal medicine and a PhD in Experimental Medicine (Endocrinology). His research applies human genetics and multi-omics to complex and pediatric diseases, including GWAS, polygenic risk scores (PRS), single-cell transcriptomics, and integrative genomics to support precision medicine and clinical translation.","sameAs":["https:\/\/x.com\/HuiQiQu"],"url":"https:\/\/blogs.bmj.com\/jmg\/author\/hqiqu\/"}]}},"_links":{"self":[{"href":"https:\/\/blogs.bmj.com\/jmg\/wp-json\/wp\/v2\/posts\/2040","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/blogs.bmj.com\/jmg\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/blogs.bmj.com\/jmg\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/blogs.bmj.com\/jmg\/wp-json\/wp\/v2\/users\/123"}],"replies":[{"embeddable":true,"href":"https:\/\/blogs.bmj.com\/jmg\/wp-json\/wp\/v2\/comments?post=2040"}],"version-history":[{"count":0,"href":"https:\/\/blogs.bmj.com\/jmg\/wp-json\/wp\/v2\/posts\/2040\/revisions"}],"wp:attachment":[{"href":"https:\/\/blogs.bmj.com\/jmg\/wp-json\/wp\/v2\/media?parent=2040"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/blogs.bmj.com\/jmg\/wp-json\/wp\/v2\/categories?post=2040"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/blogs.bmj.com\/jmg\/wp-json\/wp\/v2\/tags?post=2040"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}