{"id":1763,"date":"2022-09-20T13:52:56","date_gmt":"2022-09-20T13:52:56","guid":{"rendered":"https:\/\/blogs.bmj.com\/jmg\/?p=1763"},"modified":"2026-02-23T00:44:18","modified_gmt":"2026-02-23T00:44:18","slug":"systems-approach-to-enhance-lynch-syndrome-diagnosis-through-tumour-testing","status":"publish","type":"post","link":"https:\/\/blogs.bmj.com\/jmg\/2022\/09\/20\/systems-approach-to-enhance-lynch-syndrome-diagnosis-through-tumour-testing\/","title":{"rendered":"Systems approach to enhance Lynch syndrome diagnosis through tumour testing (Contributed by Dr. Xavier Llor)"},"content":{"rendered":"<p>Colorectal cancer<strong>\u00a0<\/strong>tumor testing<strong>\u00a0<\/strong>is recommended to pre-screen patients to determine who should undergo genetic testing to rule out Lynch syndrome, the most common colorectal cancer syndrome. However, compliance is low and most patients with abnormal results do not undergo Lynch syndrome screening. We developed a systems approach that was eventually automated to increase referral for genetic testing and ultimately Lynch syndrome diagnosis. As a result of the intervention, we were able to increase the proportion of patients undergoing genetic testing and doubled the percentage of patients diagnosed with Lynch syndrome with no referral differences across racial\/ethnic groups. (<a href=\"https:\/\/jmg.bmj.com\/content\/early\/2022\/09\/17\/jmg-2022-108770\">https:\/\/jmg.bmj.com\/content\/early\/2022\/09\/17\/jmg-2022-108770<\/a> )<\/p>\n<p><a href=\"https:\/\/blogs.bmj.com\/jmg\/2022\/09\/20\/systems-approach-to-enhance-lynch-syndrome-diagnosis-through-tumour-testing\/untitled-60\/\" rel=\"attachment wp-att-1764\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-medium wp-image-1764\" src=\"https:\/\/blogs.bmj.com\/jmg\/files\/2022\/09\/Untitled-1-300x171.png\" alt=\"\" width=\"300\" height=\"171\" srcset=\"https:\/\/blogs.bmj.com\/jmg\/files\/2022\/09\/Untitled-1-300x171.png 300w, https:\/\/blogs.bmj.com\/jmg\/files\/2022\/09\/Untitled-1-1024x583.png 1024w, https:\/\/blogs.bmj.com\/jmg\/files\/2022\/09\/Untitled-1-768x438.png 768w, https:\/\/blogs.bmj.com\/jmg\/files\/2022\/09\/Untitled-1-640x365.png 640w, https:\/\/blogs.bmj.com\/jmg\/files\/2022\/09\/Untitled-1.png 1464w\" sizes=\"auto, (max-width: 300px) 100vw, 300px\" \/><\/a><!--TrendMD v2.4.8--><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Colorectal cancer\u00a0tumor testing\u00a0is recommended to pre-screen patients to determine who should undergo genetic testing to rule out Lynch syndrome, the most common colorectal cancer syndrome. However, compliance is low and most patients with abnormal results do not undergo Lynch syndrome screening. We developed a systems approach that was eventually automated to increase referral for genetic [&#8230;]<\/p>\n<p><a class=\"btn btn-secondary understrap-read-more-link\" href=\"https:\/\/blogs.bmj.com\/jmg\/2022\/09\/20\/systems-approach-to-enhance-lynch-syndrome-diagnosis-through-tumour-testing\/\">Read More&#8230;<\/a><\/p>\n","protected":false},"author":123,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":["post-1763","post","type-post","status-publish","format-standard","hentry","category-uncategorized"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.6 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Systems approach to enhance Lynch syndrome diagnosis through tumour testing (Contributed by Dr. Xavier Llor) - JMG Contact blog<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/blogs.bmj.com\/jmg\/2022\/09\/20\/systems-approach-to-enhance-lynch-syndrome-diagnosis-through-tumour-testing\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Systems approach to enhance Lynch syndrome diagnosis through tumour testing (Contributed by Dr. Xavier Llor) - JMG Contact blog\" \/>\n<meta property=\"og:description\" content=\"Colorectal cancer\u00a0tumor testing\u00a0is recommended to pre-screen patients to determine who should undergo genetic testing to rule out Lynch syndrome, the most common colorectal cancer syndrome. However, compliance is low and most patients with abnormal results do not undergo Lynch syndrome screening. We developed a systems approach that was eventually automated to increase referral for genetic [...]Read More...\" \/>\n<meta property=\"og:url\" content=\"https:\/\/blogs.bmj.com\/jmg\/2022\/09\/20\/systems-approach-to-enhance-lynch-syndrome-diagnosis-through-tumour-testing\/\" \/>\n<meta property=\"og:site_name\" content=\"JMG Contact blog\" \/>\n<meta property=\"article:published_time\" content=\"2022-09-20T13:52:56+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2026-02-23T00:44:18+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/blogs.bmj.com\/jmg\/files\/2022\/09\/Untitled-1.png\" \/>\n\t<meta property=\"og:image:width\" content=\"1464\" \/>\n\t<meta property=\"og:image:height\" content=\"834\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/png\" \/>\n<meta name=\"author\" content=\"hqqu\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:creator\" content=\"@HuiQiQu\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"hqqu\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/blogs.bmj.com\\\/jmg\\\/2022\\\/09\\\/20\\\/systems-approach-to-enhance-lynch-syndrome-diagnosis-through-tumour-testing\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/blogs.bmj.com\\\/jmg\\\/2022\\\/09\\\/20\\\/systems-approach-to-enhance-lynch-syndrome-diagnosis-through-tumour-testing\\\/\"},\"author\":{\"name\":\"hqqu\",\"@id\":\"https:\\\/\\\/blogs.bmj.com\\\/jmg\\\/#\\\/schema\\\/person\\\/be0250f8d5b52412c3e7c222dabd591b\"},\"headline\":\"Systems approach to enhance Lynch syndrome diagnosis through tumour testing (Contributed by Dr. Xavier Llor)\",\"datePublished\":\"2022-09-20T13:52:56+00:00\",\"dateModified\":\"2026-02-23T00:44:18+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/blogs.bmj.com\\\/jmg\\\/2022\\\/09\\\/20\\\/systems-approach-to-enhance-lynch-syndrome-diagnosis-through-tumour-testing\\\/\"},\"wordCount\":122,\"commentCount\":0,\"publisher\":{\"@id\":\"https:\\\/\\\/blogs.bmj.com\\\/jmg\\\/#organization\"},\"image\":{\"@id\":\"https:\\\/\\\/blogs.bmj.com\\\/jmg\\\/2022\\\/09\\\/20\\\/systems-approach-to-enhance-lynch-syndrome-diagnosis-through-tumour-testing\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/blogs.bmj.com\\\/jmg\\\/files\\\/2022\\\/09\\\/Untitled-1-300x171.png\",\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"CommentAction\",\"name\":\"Comment\",\"target\":[\"https:\\\/\\\/blogs.bmj.com\\\/jmg\\\/2022\\\/09\\\/20\\\/systems-approach-to-enhance-lynch-syndrome-diagnosis-through-tumour-testing\\\/#respond\"]}]},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/blogs.bmj.com\\\/jmg\\\/2022\\\/09\\\/20\\\/systems-approach-to-enhance-lynch-syndrome-diagnosis-through-tumour-testing\\\/\",\"url\":\"https:\\\/\\\/blogs.bmj.com\\\/jmg\\\/2022\\\/09\\\/20\\\/systems-approach-to-enhance-lynch-syndrome-diagnosis-through-tumour-testing\\\/\",\"name\":\"Systems approach to enhance Lynch syndrome diagnosis through tumour testing (Contributed by Dr. Xavier Llor) - 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