{"id":1339,"date":"2019-09-14T13:24:08","date_gmt":"2019-09-14T13:24:08","guid":{"rendered":"https:\/\/blogs.bmj.com\/jmg\/?p=1339"},"modified":"2026-02-24T00:27:24","modified_gmt":"2026-02-24T00:27:24","slug":"rapid-proteomic-urine-assay-for-monitoring-progressive-organ-disease-in-fabry-disease","status":"publish","type":"post","link":"https:\/\/blogs.bmj.com\/jmg\/2019\/09\/14\/rapid-proteomic-urine-assay-for-monitoring-progressive-organ-disease-in-fabry-disease\/","title":{"rendered":"Rapid, proteomic urine assay for monitoring progressive organ disease in Fabry disease (Contributed by Dr Kevin Mills)"},"content":{"rendered":"

This works describes a new and non-invasive way to simultaneously monitor an inflammatory response, lysosomal dysfunction, kidney and cardiovascular disease.\u00a0 Fabry Disease is a condition where we cannot breakdown a glycolipid.\u00a0 This builds up in the body causing kidney and\/or cardiovascular damage. Plasma lyso-Gb3 is the general lipid biomarker used to monitor response to treatment but it does not tell us anything about what organs are affected or which systems are responding. Our simple, 10-minute, targeted proteomic urine test measures many biomarkers at once and allows us to monitor organ damage without the need for invasive or time consuming procedures. (https:\/\/jmg.bmj.com\/content\/early\/2019\/09\/12\/jmedgenet-2019-106030<\/a> )<\/p>\n

\"\"<\/a>\"\"<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

This works describes a new and non-invasive way to simultaneously monitor an inflammatory response, lysosomal dysfunction, kidney and cardiovascular disease.\u00a0 Fabry Disease is a condition where we cannot breakdown a glycolipid.\u00a0 This builds up in the body causing kidney and\/or cardiovascular damage. Plasma lyso-Gb3 is the general lipid biomarker used to monitor response to treatment […]<\/p>\n

Read More…<\/a><\/p>\n","protected":false},"author":123,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":["post-1339","post","type-post","status-publish","format-standard","hentry","category-uncategorized"],"yoast_head":"\nRapid, proteomic urine assay for monitoring progressive organ disease in Fabry disease (Contributed by Dr Kevin Mills) - JMG Contact blog<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/blogs.bmj.com\/jmg\/2019\/09\/14\/rapid-proteomic-urine-assay-for-monitoring-progressive-organ-disease-in-fabry-disease\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Rapid, proteomic urine assay for monitoring progressive organ disease in Fabry disease (Contributed by Dr Kevin Mills) - JMG Contact blog\" \/>\n<meta property=\"og:description\" content=\"This works describes a new and non-invasive way to simultaneously monitor an inflammatory response, lysosomal dysfunction, kidney and cardiovascular disease.\u00a0 Fabry Disease is a condition where we cannot breakdown a glycolipid.\u00a0 This builds up in the body causing kidney and\/or cardiovascular damage. Plasma lyso-Gb3 is the general lipid biomarker used to monitor response to treatment [...]Read More...\" \/>\n<meta property=\"og:url\" content=\"https:\/\/blogs.bmj.com\/jmg\/2019\/09\/14\/rapid-proteomic-urine-assay-for-monitoring-progressive-organ-disease-in-fabry-disease\/\" \/>\n<meta property=\"og:site_name\" content=\"JMG Contact blog\" \/>\n<meta property=\"article:published_time\" content=\"2019-09-14T13:24:08+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2026-02-24T00:27:24+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/blogs.bmj.com\/jmg\/files\/2019\/09\/26543510563_7b11d59f3f_o.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"1959\" \/>\n\t<meta property=\"og:image:height\" content=\"1128\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"hqqu\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:creator\" content=\"@HuiQiQu\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"hqqu\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/blogs.bmj.com\\\/jmg\\\/2019\\\/09\\\/14\\\/rapid-proteomic-urine-assay-for-monitoring-progressive-organ-disease-in-fabry-disease\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/blogs.bmj.com\\\/jmg\\\/2019\\\/09\\\/14\\\/rapid-proteomic-urine-assay-for-monitoring-progressive-organ-disease-in-fabry-disease\\\/\"},\"author\":{\"name\":\"hqqu\",\"@id\":\"https:\\\/\\\/blogs.bmj.com\\\/jmg\\\/#\\\/schema\\\/person\\\/be0250f8d5b52412c3e7c222dabd591b\"},\"headline\":\"Rapid, proteomic urine assay for monitoring progressive organ disease in Fabry disease (Contributed by Dr Kevin Mills)\",\"datePublished\":\"2019-09-14T13:24:08+00:00\",\"dateModified\":\"2026-02-24T00:27:24+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/blogs.bmj.com\\\/jmg\\\/2019\\\/09\\\/14\\\/rapid-proteomic-urine-assay-for-monitoring-progressive-organ-disease-in-fabry-disease\\\/\"},\"wordCount\":126,\"commentCount\":0,\"publisher\":{\"@id\":\"https:\\\/\\\/blogs.bmj.com\\\/jmg\\\/#organization\"},\"image\":{\"@id\":\"https:\\\/\\\/blogs.bmj.com\\\/jmg\\\/2019\\\/09\\\/14\\\/rapid-proteomic-urine-assay-for-monitoring-progressive-organ-disease-in-fabry-disease\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/blogs.bmj.com\\\/jmg\\\/files\\\/2019\\\/09\\\/26543510563_7b11d59f3f_o-300x173.jpg\",\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"CommentAction\",\"name\":\"Comment\",\"target\":[\"https:\\\/\\\/blogs.bmj.com\\\/jmg\\\/2019\\\/09\\\/14\\\/rapid-proteomic-urine-assay-for-monitoring-progressive-organ-disease-in-fabry-disease\\\/#respond\"]}]},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/blogs.bmj.com\\\/jmg\\\/2019\\\/09\\\/14\\\/rapid-proteomic-urine-assay-for-monitoring-progressive-organ-disease-in-fabry-disease\\\/\",\"url\":\"https:\\\/\\\/blogs.bmj.com\\\/jmg\\\/2019\\\/09\\\/14\\\/rapid-proteomic-urine-assay-for-monitoring-progressive-organ-disease-in-fabry-disease\\\/\",\"name\":\"Rapid, proteomic urine assay for monitoring progressive organ disease in Fabry disease (Contributed by Dr Kevin Mills) - 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