{"id":1273,"date":"2019-04-22T14:27:30","date_gmt":"2019-04-22T14:27:30","guid":{"rendered":"https:\/\/blogs.bmj.com\/jmg\/?p=1273"},"modified":"2026-02-24T00:42:12","modified_gmt":"2026-02-24T00:42:12","slug":"multivariate-genome-wide-association-study-of-rapid-automatized-naming-and-rapid-alternating-stimulus-in-hispanic-american-and-african-american-youth","status":"publish","type":"post","link":"https:\/\/blogs.bmj.com\/jmg\/2019\/04\/22\/multivariate-genome-wide-association-study-of-rapid-automatized-naming-and-rapid-alternating-stimulus-in-hispanic-american-and-african-american-youth\/","title":{"rendered":"Multivariate genome-wide association study of rapid automatized naming and rapid alternating stimulus in Hispanic American and African American youth (Contributed by Dr. Jeffrey R. Gruen)"},"content":{"rendered":"<p>Rapid automatized naming (RAN) and rapid alternating stimulus (RAS) are measures that involve naming familiar items quickly and accurately. They are also reliable predictors of dyslexia. The high correlations between RAN, RAS, and reading could be due to genetic factors that they share in common, and that modify an underlying biological mechanism. We describe genetic variants encoded on chromosome 10 that correlate with RAN, RAS, reading, and volume of a reading center in the brain.\u00a0 The location of these variants on the chromosome suggest they could be informative markers for genetic factors that modify the instructions for turning on and off a gene called renelase, which has not been previously linked to reading. (<a href=\"https:\/\/jmg.bmj.com\/content\/early\/2019\/04\/17\/jmedgenet-2018-105874\">https:\/\/jmg.bmj.com\/content\/early\/2019\/04\/17\/jmedgenet-2018-105874<\/a> )<\/p>\n<p><a href=\"https:\/\/blogs.bmj.com\/jmg\/2019\/04\/22\/multivariate-genome-wide-association-study-of-rapid-automatized-naming-and-rapid-alternating-stimulus-in-hispanic-american-and-african-american-youth\/untitled-17\/\" rel=\"attachment wp-att-1274\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-medium wp-image-1274\" src=\"https:\/\/blogs.bmj.com\/jmg\/files\/2019\/04\/Untitled-300x182.jpg\" alt=\"\" width=\"300\" height=\"182\" srcset=\"https:\/\/blogs.bmj.com\/jmg\/files\/2019\/04\/Untitled-300x182.jpg 300w, https:\/\/blogs.bmj.com\/jmg\/files\/2019\/04\/Untitled-768x465.jpg 768w, https:\/\/blogs.bmj.com\/jmg\/files\/2019\/04\/Untitled-1024x620.jpg 1024w, https:\/\/blogs.bmj.com\/jmg\/files\/2019\/04\/Untitled-640x387.jpg 640w, https:\/\/blogs.bmj.com\/jmg\/files\/2019\/04\/Untitled.jpg 1916w\" sizes=\"auto, (max-width: 300px) 100vw, 300px\" \/><\/a><!--TrendMD v2.4.8--><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Rapid automatized naming (RAN) and rapid alternating stimulus (RAS) are measures that involve naming familiar items quickly and accurately. They are also reliable predictors of dyslexia. The high correlations between RAN, RAS, and reading could be due to genetic factors that they share in common, and that modify an underlying biological mechanism. We describe genetic [&#8230;]<\/p>\n<p><a class=\"btn btn-secondary understrap-read-more-link\" href=\"https:\/\/blogs.bmj.com\/jmg\/2019\/04\/22\/multivariate-genome-wide-association-study-of-rapid-automatized-naming-and-rapid-alternating-stimulus-in-hispanic-american-and-african-american-youth\/\">Read More&#8230;<\/a><\/p>\n","protected":false},"author":123,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":["post-1273","post","type-post","status-publish","format-standard","hentry","category-uncategorized"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.6 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Multivariate genome-wide association study of rapid automatized naming and rapid alternating stimulus in Hispanic American and African American youth (Contributed by Dr. Jeffrey R. Gruen) - JMG Contact blog<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/blogs.bmj.com\/jmg\/2019\/04\/22\/multivariate-genome-wide-association-study-of-rapid-automatized-naming-and-rapid-alternating-stimulus-in-hispanic-american-and-african-american-youth\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Multivariate genome-wide association study of rapid automatized naming and rapid alternating stimulus in Hispanic American and African American youth (Contributed by Dr. Jeffrey R. Gruen) - JMG Contact blog\" \/>\n<meta property=\"og:description\" content=\"Rapid automatized naming (RAN) and rapid alternating stimulus (RAS) are measures that involve naming familiar items quickly and accurately. They are also reliable predictors of dyslexia. The high correlations between RAN, RAS, and reading could be due to genetic factors that they share in common, and that modify an underlying biological mechanism. We describe genetic [...]Read More...\" \/>\n<meta property=\"og:url\" content=\"https:\/\/blogs.bmj.com\/jmg\/2019\/04\/22\/multivariate-genome-wide-association-study-of-rapid-automatized-naming-and-rapid-alternating-stimulus-in-hispanic-american-and-african-american-youth\/\" \/>\n<meta property=\"og:site_name\" content=\"JMG Contact blog\" \/>\n<meta property=\"article:published_time\" content=\"2019-04-22T14:27:30+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2026-02-24T00:42:12+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/blogs.bmj.com\/jmg\/files\/2019\/04\/Untitled.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"1916\" \/>\n\t<meta property=\"og:image:height\" content=\"1160\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"hqqu\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:creator\" content=\"@HuiQiQu\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"hqqu\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/blogs.bmj.com\\\/jmg\\\/2019\\\/04\\\/22\\\/multivariate-genome-wide-association-study-of-rapid-automatized-naming-and-rapid-alternating-stimulus-in-hispanic-american-and-african-american-youth\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/blogs.bmj.com\\\/jmg\\\/2019\\\/04\\\/22\\\/multivariate-genome-wide-association-study-of-rapid-automatized-naming-and-rapid-alternating-stimulus-in-hispanic-american-and-african-american-youth\\\/\"},\"author\":{\"name\":\"hqqu\",\"@id\":\"https:\\\/\\\/blogs.bmj.com\\\/jmg\\\/#\\\/schema\\\/person\\\/be0250f8d5b52412c3e7c222dabd591b\"},\"headline\":\"Multivariate genome-wide association study of rapid automatized naming and rapid alternating stimulus in Hispanic American and African American youth (Contributed by Dr. Jeffrey R. 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