https:\/\/jmg.bmj.com\/content\/early\/2019\/02\/11\/jmedgenet-2018-105361<\/a> )<\/p>\n","protected":false},"excerpt":{"rendered":"Hereditary diffuse gastric cancer (HDGC) is a cancer predisposition syndrome with significantly elevated life-time risks of gastric and breast cancer due to loss-of-function (LOF) germline variants of the CDH1 gene. There is considerable variability across affected families in its clinical manifestations including age-of-onset and cancer phenotype. In this study, we identified associations between location of […]<\/p>\n
Read More…<\/a><\/p>\n","protected":false},"author":123,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":["post-1235","post","type-post","status-publish","format-standard","hentry","category-uncategorized"],"yoast_head":"\nAssociations of CDH1 germline variant location and cancer phenotype in families with hereditary diffuse gastric cancer (HDGC) (Contributed by Dr. Udo Rudloff) - JMG Contact blog<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/blogs.bmj.com\/jmg\/2019\/02\/12\/associations-of-cdh1-germline-variant-location-and-cancer-phenotype-in-families-with-hereditary-diffuse-gastric-cancer-hdgc\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Associations of CDH1 germline variant location and cancer phenotype in families with hereditary diffuse gastric cancer (HDGC) (Contributed by Dr. Udo Rudloff) - JMG Contact blog\" \/>\n<meta property=\"og:description\" content=\"Hereditary diffuse gastric cancer (HDGC) is a cancer predisposition syndrome with significantly elevated life-time risks of gastric and breast cancer due to loss-of-function (LOF) germline variants of the CDH1 gene. 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