http:\/\/jmg.bmj.com\/content\/early\/2018\/02\/22\/jmedgenet-2017-104744<\/a> )<\/p>\n","protected":false},"excerpt":{"rendered":"Most MLH1 germline defects predisposing for Lynch Syndrome constitute sequence changes or deletions in the coding region. Searching for variants in the MLH1 promoter causative for silencing or methylation, we sequenced the extended MLH1 promoter region for 480 colorectal cancer patients and 1,150 controls. We detected ten rare promoter variants. One was found in in […]<\/p>\n
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