Google DeepMind has released the AlphaGenome Atlas, a large-scale resource containing precomputed predictions for nearly every possible single-nucleotide substitution in the human genome. The atlas extends the AlphaGenome framework to genome-wide variant interpretation, including predicted effects on gene expression, splicing, chromatin accessibility, and other regulatory features. The resource may be particularly useful for prioritizing noncoding variants in rare disease and complex-trait studies. (https://deepmind.google/blog/alphagenome-atlas-a-predictive-map-of-every-possible-dna-letter-change-in-the-human-genome/)