1.0Hearthttps://blogs.bmj.com/heartHearthttps://blogs.bmj.com/heartAldo-DHF: spironolactone improves diastolic function - Heartrich600338<blockquote class="wp-embedded-content" data-secret="k5aZvJumKC"><a href="https://blogs.bmj.com/heart/2013/03/02/aldo-dhf-spironolactone-improves-diastolic-function/">Aldo-DHF: spironolactone improves diastolic function</a></blockquote><iframe sandbox="allow-scripts" security="restricted" src="https://blogs.bmj.com/heart/2013/03/02/aldo-dhf-spironolactone-improves-diastolic-function/embed/#?secret=k5aZvJumKC" width="600" height="338" title="“Aldo-DHF: spironolactone improves diastolic function” — Heart" data-secret="k5aZvJumKC" frameborder="0" marginwidth="0" marginheight="0" scrolling="no" class="wp-embedded-content"></iframe><script type="text/javascript">
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Heart failure with preserved ejection fraction (HF-PEF) accounts for more than 50% of heart failure cases. To date, medical therapy has failed to show improvements in diastolic dysfunction, cardiac remodelling, or cardiovascular outcomes. As mineralocorticoid receptor activation by aldosterone contributes to the pathophysiology of HF through several different mechanisms, the Aldosterone Receptor Blockade in Diastolic [...]Read More...