23 Apr, 13 | by Dr Dean Jenkins
There was an excellent update on type 2 diabetes in children and young adults by Professor Melanie Davies at the weekend in Leicester as part of the Postgraduate Diploma in Diabetes lecture series. She outlined the current burden of the disease, its risks and gave an account of the ongoing research at University of Leicester. This is an important area to consider and quite specialised involving poor physical health, poor diet, mental health and family issues let alone the presence of retinopathy, fatty liver and cardiovascular risks at presentation. “It can be a lot more complicated than a Type 1 Diabetes Clinic”, she said.
The International Society for Pediatric and Adolescent Diabetes (ISPAD) have published guidelines on Type 2 Diabetes in children and adults which acknowledge the association with obesity and insulin resistance, and the increasing public health burden changing the pattern of presentation of diabetes in the young.
“T2DM is commonly associated with other features of the insulin resistance syndrome [hyperlipidemia, hypertension, acanthosis nigricans, ovarian hyperandrogenism, non-alcoholic fatty liver disease (NAFLD)] … In Hong Kong > 90% of young onset diabetes is T2DM.” 
Professor Davies also gave an overview of the EXPEDITION study – Early Detection of Cardiovascular Dysfunction and Health Behaviours in the Young with Type 2 Diabetes – that they are running at Leicester with some examples of the marked cardiovascular changes in these young people detected with cardiac MRI.
1. Rosenbloom AL, Silverstein JH, Amemiya S, Zeitler, P, Klingensmith, G. Type 2 diabetes in the child and adolescent. Pediatric Diabetes 2009: 10 (Suppl. 12): 17 – 32