{"id":701,"date":"2013-11-26T14:33:59","date_gmt":"2013-11-26T14:33:59","guid":{"rendered":"https:\/\/blogs.bmj.com\/case-reports\/?p=701"},"modified":"2013-11-26T14:33:59","modified_gmt":"2013-11-26T14:33:59","slug":"three-cases-of-severely-disseminated-staphylococcus-aureus-infection-in-patients-treated-with-tocilizumab","status":"publish","type":"post","link":"https:\/\/blogs.bmj.com\/case-reports\/2013\/11\/26\/three-cases-of-severely-disseminated-staphylococcus-aureus-infection-in-patients-treated-with-tocilizumab\/","title":{"rendered":"Three cases of severely disseminated Staphylococcus aureus infection in patients treated with tocilizumab"},"content":{"rendered":"<p>These cases illustrate a number of important points of relevance to acute and general medical physicians as well as in specialties such as Rheumatology. Firstly, patients who are on anti-IL-6 medications may present in a different and less florid way when infected systemically with Staphylococcus aureus than immunocompetent patients. Secondly, they provide a reminder to doctors to ask about any injected therapies that the patient may have received in the last 6 months when taking a drug history. Thirdly, they give a warning to prescribers of drugs such as tocilizumab that such bacterial dissemination can occur, and to be particularly wary in the presence of likely risk factors, such as indwelling prosthetic material or previous invasive disease caused by Staphylococcus aureus.<\/p>\n<p><em>Reviewer<br \/>\nDr Thomas C Morris<br \/>\nNHS &#8211;\u00a0Infectious Diseases<\/em><\/p>\n<p><a title=\"Three cases of severely disseminated Staphylococcus aureus infection in patients treated with tocilizumab\" href=\"http:\/\/casereports.bmj.com\/content\/2013\/bcr-2012-007413.full?sid=d718d3e2-d90b-45cb-b233-01000d27d9bb\" target=\"_blank\">Three cases of severely disseminated Staphylococcus aureus infection in patients treated with tocilizumab<\/a><!--TrendMD v2.4.8--><\/p>\n","protected":false},"excerpt":{"rendered":"<p>These cases illustrate a number of important points of relevance to acute and general medical physicians as well as in specialties such as Rheumatology. Firstly, patients who are on anti-IL-6 medications may present in a different and less florid way when infected systemically with Staphylococcus aureus than immunocompetent patients. Secondly, they provide a reminder to [&#8230;]<\/p>\n<p><a class=\"btn btn-secondary understrap-read-more-link\" href=\"https:\/\/blogs.bmj.com\/case-reports\/2013\/11\/26\/three-cases-of-severely-disseminated-staphylococcus-aureus-infection-in-patients-treated-with-tocilizumab\/\">Read More&#8230;<\/a><\/p>\n","protected":false},"author":206,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[203,2656,2654],"tags":[],"class_list":["post-701","post","type-post","status-publish","format-standard","hentry","category-editors-choice","category-patients-perspective","category-reviewers-comment"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.6 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Three cases of severely disseminated Staphylococcus aureus infection in patients treated with tocilizumab - BMJ Case Reports blog<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/blogs.bmj.com\/case-reports\/2013\/11\/26\/three-cases-of-severely-disseminated-staphylococcus-aureus-infection-in-patients-treated-with-tocilizumab\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Three cases of severely disseminated Staphylococcus aureus infection in patients treated with tocilizumab - BMJ Case Reports blog\" \/>\n<meta property=\"og:description\" content=\"These cases illustrate a number of important points of relevance to acute and general medical physicians as well as in specialties such as Rheumatology. Firstly, patients who are on anti-IL-6 medications may present in a different and less florid way when infected systemically with Staphylococcus aureus than immunocompetent patients. Secondly, they provide a reminder to [...]Read More...\" \/>\n<meta property=\"og:url\" content=\"https:\/\/blogs.bmj.com\/case-reports\/2013\/11\/26\/three-cases-of-severely-disseminated-staphylococcus-aureus-infection-in-patients-treated-with-tocilizumab\/\" \/>\n<meta property=\"og:site_name\" content=\"BMJ Case Reports blog\" \/>\n<meta property=\"article:published_time\" content=\"2013-11-26T14:33:59+00:00\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/blogs.bmj.com\\\/case-reports\\\/2013\\\/11\\\/26\\\/three-cases-of-severely-disseminated-staphylococcus-aureus-infection-in-patients-treated-with-tocilizumab\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/blogs.bmj.com\\\/case-reports\\\/2013\\\/11\\\/26\\\/three-cases-of-severely-disseminated-staphylococcus-aureus-infection-in-patients-treated-with-tocilizumab\\\/\"},\"author\":{\"name\":\"\",\"@id\":\"\"},\"headline\":\"Three cases of severely disseminated Staphylococcus aureus infection in patients treated with tocilizumab\",\"datePublished\":\"2013-11-26T14:33:59+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/blogs.bmj.com\\\/case-reports\\\/2013\\\/11\\\/26\\\/three-cases-of-severely-disseminated-staphylococcus-aureus-infection-in-patients-treated-with-tocilizumab\\\/\"},\"wordCount\":155,\"commentCount\":0,\"publisher\":{\"@id\":\"https:\\\/\\\/blogs.bmj.com\\\/case-reports\\\/#organization\"},\"articleSection\":[\"Editors choice\",\"Patient's Perspective\",\"Reviewer's comment\"],\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"CommentAction\",\"name\":\"Comment\",\"target\":[\"https:\\\/\\\/blogs.bmj.com\\\/case-reports\\\/2013\\\/11\\\/26\\\/three-cases-of-severely-disseminated-staphylococcus-aureus-infection-in-patients-treated-with-tocilizumab\\\/#respond\"]}]},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/blogs.bmj.com\\\/case-reports\\\/2013\\\/11\\\/26\\\/three-cases-of-severely-disseminated-staphylococcus-aureus-infection-in-patients-treated-with-tocilizumab\\\/\",\"url\":\"https:\\\/\\\/blogs.bmj.com\\\/case-reports\\\/2013\\\/11\\\/26\\\/three-cases-of-severely-disseminated-staphylococcus-aureus-infection-in-patients-treated-with-tocilizumab\\\/\",\"name\":\"Three cases of severely disseminated Staphylococcus aureus infection in patients treated with tocilizumab - 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