Smith and colleagues present a fine piece of detective work around a 2 month old infant with an initially puzzling neurological presentation. They unearth valuable learning points: Young infants are particularly vulnerable due to the susceptibility of their gut to colonisation due to immature intestinal flora and lack of clostridium-inhibiting bile acids. This is in […]
Month: October 2010
Fulminant hepatic failure in a patient with advanced extragonadal germ cell tumour
This is a heartening report which reflects what a diligent team of clinicians can achieve in terms of patient management. It is about a 36 year old man who noticed swelling in his right lower limb and eventually he was found to have not only a deep vein thrombosis to explain the right limb swelling […]
Malabsorption of antimycobacterial drugs as a cause of treatment failure in tuberculosis
The case raises very interesting questions: I wonder how commonly is this problem noticed in the developing world where treatment failure with antitubercular therapy ATT is not uncommon? Why does ATT get selectively malabsorbed even without any other signs of malabsorption? Malabsorption of antimycobacterial drugs as a cause of treatment failure in tuberculosis […]