{"id":577,"date":"2025-03-04T07:38:46","date_gmt":"2025-03-04T07:38:46","guid":{"rendered":"https:\/\/blogs.bmj.com\/bmjopensem\/?p=577"},"modified":"2025-03-04T07:38:46","modified_gmt":"2025-03-04T07:38:46","slug":"a-peek-behind-the-study-with-adrian-martineau","status":"publish","type":"post","link":"https:\/\/blogs.bmj.com\/bmjopensem\/2025\/03\/04\/a-peek-behind-the-study-with-adrian-martineau\/","title":{"rendered":"A PEEK BEHIND THE STUDY &#8211; WITH ADRIAN MARTINEAU"},"content":{"rendered":"<p><span style=\"color: #ff0000\"><strong>Ganmaa et al. Influence of vitamin D supplementation on muscle strength and exercise capacity in Mongolian schoolchildren: secondary outcomes from a randomised controlled trial: BMJ Open Sport &amp; Exercise Medicine 2024;10:e002018.<\/strong><\/span><\/p>\n<p><span style=\"color: #ff0000\"><strong>Middelkoop et al. Influence of vitamin D supplementation on muscle strength and exercise capacity in South African schoolchildren: secondary outcomes from a randomised controlled trial (ViDiKids): BMJ Open Sport &amp; Exercise Medicine 2024;10:e002019.<\/strong><\/span><\/p>\n<p><!--more--><\/p>\n<p>&nbsp;<\/p>\n<p>The full articles can be found <a href=\"https:\/\/bmjopensem.bmj.com\/content\/10\/3\/e002018\">here <\/a>and <a href=\"https:\/\/bmjopensem.bmj.com\/content\/10\/3\/e002019\">here<\/a>.<\/p>\n<p>&nbsp;<\/p>\n<h5><strong>Tell us more about yourself and the author team.<\/strong><\/h5>\n<p style=\"font-weight: 400\">We are a team of doctors and clinical trialists from the UK, South Africa, and Mongolia studying vitamin D&#8217;s effects on children\u2019s health.<\/p>\n<h5><strong>What is the story behind your study?<\/strong><\/h5>\n<p style=\"font-weight: 400\">Vitamin D has long been important for calcium homeostasis and musculoskeletal health, and several observational studies have reported associations between lower vitamin D status and reduced exercise tolerance \/ physical fitness. However, large clinical trials have been lacking in testing for a cause-effect relationship.<\/p>\n<h5><strong>In your own words, what did you find?<\/strong><\/h5>\n<p style=\"font-weight: 400\">We did two placebo-controlled weekly vitamin D supplementation trials in primary schoolchildren, administered for 3 years \u2013 one in Cape Town, South Africa, the other in Ulaanbaatar, Mongolia. In both studies, the trial supplements effectively boosted serum 25-hydroxyvitamin D concentrations of children randomly selected to receive them. However, this improvement in vitamin D status was not associated with any improvement in outcomes studied, including exercise tolerance (20m shuttle runs), grip strength and explosive leg power (measured using standing long jump).<\/p>\n<h5><strong>What was the main challenge you faced in your study?<\/strong><\/h5>\n<p style=\"font-weight: 400\">Maintaining adherence to study medication for 3 years was a potential challenge, but we achieved this by directly observing supplement administration at participating schools.<\/p>\n<h5><strong>If there is one take-home message from your study, what would that be?<\/strong><\/h5>\n<p style=\"font-weight: 400\">Weekly vitamin D supplementation effectively improved the vitamin D status of schoolchildren in South Africa and Mongolia, but this did not result in improved exercise tolerance or muscle strength.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Ganmaa et al. Influence of vitamin D supplementation on muscle strength and exercise capacity in Mongolian schoolchildren: secondary outcomes from a randomised controlled trial: BMJ Open Sport &amp; Exercise Medicine 2024;10:e002018. Middelkoop et al. Influence of vitamin D supplementation on muscle strength and exercise capacity in South African schoolchildren: secondary outcomes from a randomised controlled [&#8230;]<\/p>\n<p><a class=\"btn btn-secondary understrap-read-more-link\" href=\"https:\/\/blogs.bmj.com\/bmjopensem\/2025\/03\/04\/a-peek-behind-the-study-with-adrian-martineau\/\">Read More&#8230;<\/a><\/p>\n","protected":false},"author":455,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[10],"tags":[],"class_list":["post-577","post","type-post","status-publish","format-standard","hentry","category-a-peek-behind-the-study"],"_links":{"self":[{"href":"https:\/\/blogs.bmj.com\/bmjopensem\/wp-json\/wp\/v2\/posts\/577","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/blogs.bmj.com\/bmjopensem\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/blogs.bmj.com\/bmjopensem\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/blogs.bmj.com\/bmjopensem\/wp-json\/wp\/v2\/users\/455"}],"replies":[{"embeddable":true,"href":"https:\/\/blogs.bmj.com\/bmjopensem\/wp-json\/wp\/v2\/comments?post=577"}],"version-history":[{"count":0,"href":"https:\/\/blogs.bmj.com\/bmjopensem\/wp-json\/wp\/v2\/posts\/577\/revisions"}],"wp:attachment":[{"href":"https:\/\/blogs.bmj.com\/bmjopensem\/wp-json\/wp\/v2\/media?parent=577"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/blogs.bmj.com\/bmjopensem\/wp-json\/wp\/v2\/categories?post=577"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/blogs.bmj.com\/bmjopensem\/wp-json\/wp\/v2\/tags?post=577"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}