{"id":134,"date":"2021-07-23T08:53:25","date_gmt":"2021-07-23T07:53:25","guid":{"rendered":"https:\/\/blogs.bmj.com\/bmjopensem\/?p=134"},"modified":"2021-07-23T08:53:25","modified_gmt":"2021-07-23T07:53:25","slug":"a-peek-behind-the-study-with-kimberly-harmon","status":"publish","type":"post","link":"https:\/\/blogs.bmj.com\/bmjopensem\/2021\/07\/23\/a-peek-behind-the-study-with-kimberly-harmon\/","title":{"rendered":"A PEEK BEHIND THE STUDY &#8230; WITH KIMBERLY HARMON"},"content":{"rendered":"<dl>\n<dd>\n<div id=\"node139801\" class=\"highwire-article-citation highwire-citation-type-highwire-article\" data-node-nid=\"139801\" data-pisa=\"bmjosem;7\/2\/e001137\" data-pisa-master=\"bmjosem;7\/2\/e001137\" data-apath=\"\/bmjosem\/7\/2\/e001137.atom\">\n<div class=\"highwire-cite highwire-cite-highwire-article highwire-citation-v1-cp clearfix bmjj-article-citation\">\n<div class=\"highwire-cite-authors\"><span style=\"color: #ff0000\"><strong><span class=\"highwire-citation-authors\"><span class=\"highwire-citation-author first\" data-delta=\"0\"><span class=\"nlm-surname\">Harmon<\/span> K<\/span>, <span class=\"highwire-citation-author\" data-delta=\"1\"><span class=\"nlm-surname\">de St Maurice<\/span> AM<\/span>, <span class=\"highwire-citation-author\" data-delta=\"2\"><span class=\"nlm-surname\">Brady<\/span> AC<\/span><\/span><\/strong><span class=\"citation-et\"><strong>, et al.<\/strong>\u00a0<\/span>Surveillance testing for SARS-COV-2 infection in an asymptomatic athlete population: a prospective cohort study with 123 362 tests and 23 463 paired RT-PCR\/antigen samples.\u00a0<span class=\"highwire-cite-metadata-journal highwire-cite-metadata\">BMJ Open Sport &amp; Exercise Medicine <\/span><span class=\"highwire-cite-metadata-year highwire-cite-metadata\">2021;<\/span><span class=\"highwire-cite-metadata-volume highwire-cite-metadata\">7:<\/span><span class=\"highwire-cite-metadata-elocation-id highwire-cite-metadata\">e001137. <\/span><span class=\"highwire-cite-metadata-doi highwire-cite-metadata\"><span class=\"label\">doi:<\/span> 10.1136\/bmjsem-2021-001137<\/span><\/span><\/div>\n<\/div>\n<\/div>\n<\/dd>\n<\/dl>\n<p><!--more--><\/p>\n<p><a href=\"https:\/\/bmjopensem.bmj.com\/content\/7\/2\/e001137\">The full paper can be found here.<\/a><\/p>\n<p>&nbsp;<\/p>\n<figure id=\"attachment_135\" aria-describedby=\"caption-attachment-135\" style=\"width: 276px\" class=\"wp-caption alignnone\"><img loading=\"lazy\" decoding=\"async\" class=\"size-medium wp-image-135\" src=\"http:\/\/blogs.bmj.com\/bmjopensem\/files\/2021\/07\/16-Harmon-et-al-276x300.jpg\" alt=\"\" width=\"276\" height=\"300\" srcset=\"https:\/\/blogs.bmj.com\/bmjopensem\/files\/2021\/07\/16-Harmon-et-al-276x300.jpg 276w, https:\/\/blogs.bmj.com\/bmjopensem\/files\/2021\/07\/16-Harmon-et-al-941x1024.jpg 941w, https:\/\/blogs.bmj.com\/bmjopensem\/files\/2021\/07\/16-Harmon-et-al-768x836.jpg 768w, https:\/\/blogs.bmj.com\/bmjopensem\/files\/2021\/07\/16-Harmon-et-al.jpg 1177w\" sizes=\"auto, (max-width: 276px) 100vw, 276px\" \/><figcaption id=\"caption-attachment-135\" class=\"wp-caption-text\">@DrKimHarmon<\/figcaption><\/figure>\n<p>&nbsp;<\/p>\n<h5><strong>Tell us more about yourself and the author team.<\/strong><\/h5>\n<p>The author team consists of the principal investigator at each of the institutions that participated, along with key infectious disease consultants that were part of the Pac-12 COVID-19 Advisory Committee and a biostatistician. The infectious disease consultants (Annabelle de St. Maurice, Sankar Swaminathan, Adam Brady and John Swartzberg (listed in acknowledgements) were critical in educating us on key infectious disease and public health concepts and really guided and moulded our conference COVID-19 policies. At the beginning of the pandemic, we met 2 \u2013 3 times a week and at least once a week. They were very generous with their time and knowledge. The collaboration between physicians, athletic trainers, infectious disease specialists and public health specialists was essential.<\/p>\n<p>&nbsp;<\/p>\n<figure id=\"attachment_136\" aria-describedby=\"caption-attachment-136\" style=\"width: 300px\" class=\"wp-caption alignnone\"><img loading=\"lazy\" decoding=\"async\" class=\"size-medium wp-image-136\" src=\"http:\/\/blogs.bmj.com\/bmjopensem\/files\/2021\/07\/16-Harmon-et-al-02-300x176.png\" alt=\"\" width=\"300\" height=\"176\" srcset=\"https:\/\/blogs.bmj.com\/bmjopensem\/files\/2021\/07\/16-Harmon-et-al-02-300x176.png 300w, https:\/\/blogs.bmj.com\/bmjopensem\/files\/2021\/07\/16-Harmon-et-al-02.png 499w\" sizes=\"auto, (max-width: 300px) 100vw, 300px\" \/><figcaption id=\"caption-attachment-136\" class=\"wp-caption-text\">The full team working through Zoom<\/figcaption><\/figure>\n<p>&nbsp;<\/p>\n<h5><strong>What is the story behind your study?<\/strong><\/h5>\n<p>When we were trying to figure out how to get athlete\u2019s on the field\/court\/pitch, it became apparent that any strategy would need to involve testing for asymptomatic infection in our athletes to prevent spread during sport and training. PCR testing with 24-hour turn-around was not available at most institutions at the beginning of the pandemic, and we wondered if more frequent antigen testing would be just as good or better. Initially, antigen tests were unavailable to us, but then we worked with the Quidel corporation to get antigen tests. As part of our commitment to Quidel, to the university presidents and the athletes, we set out to study the effectiveness of testing in different ways so that our results could be used in other settings like schools and workplaces.<\/p>\n<p>&nbsp;<\/p>\n<h5><strong>In your own words, what did you find?<\/strong><\/h5>\n<p>We knew that PCR testing was more sensitive for low viral loads than antigen testing before starting the study. We found out that PCR testing three times a week is roughly equivalent to daily antigen testing and that if you are PCR testing 4 times a week, there is little benefit to adding antigen testing. In addition, it appears that if PCR test turn-around time is longer than 24 hours, antigen testing may be superior.<\/p>\n<p>&nbsp;<\/p>\n<h5><strong>What was the main challenge you faced in your study?<\/strong><\/h5>\n<p>Getting all the results into a database was challenging, given the sheer number of tests and the different systems used at each institution. Initially, PCR results were entered manually, but we eventually figured out how to have this automated.<\/p>\n<p>&nbsp;<\/p>\n<h5><strong>If there is one take-home message from your study, what would that be?<\/strong><\/h5>\n<p>Testing (PCR or antigen) can identify infection earlier than not testing and prevent spread, but, at the end of the day, you can\u2019t test your way out of a pandemic!<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Harmon K, de St Maurice AM, Brady AC, et al.\u00a0Surveillance testing for SARS-COV-2 infection in an asymptomatic athlete population: a prospective cohort study with 123 362 tests and 23 463 paired RT-PCR\/antigen samples.\u00a0BMJ Open Sport &amp; Exercise Medicine 2021;7:e001137. doi: 10.1136\/bmjsem-2021-001137 [&#8230;]<\/p>\n<p><a class=\"btn btn-secondary understrap-read-more-link\" href=\"https:\/\/blogs.bmj.com\/bmjopensem\/2021\/07\/23\/a-peek-behind-the-study-with-kimberly-harmon\/\">Read More&#8230;<\/a><\/p>\n","protected":false},"author":455,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[10],"tags":[79],"class_list":["post-134","post","type-post","status-publish","format-standard","hentry","category-a-peek-behind-the-study","tag-covid"],"_links":{"self":[{"href":"https:\/\/blogs.bmj.com\/bmjopensem\/wp-json\/wp\/v2\/posts\/134","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/blogs.bmj.com\/bmjopensem\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/blogs.bmj.com\/bmjopensem\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/blogs.bmj.com\/bmjopensem\/wp-json\/wp\/v2\/users\/455"}],"replies":[{"embeddable":true,"href":"https:\/\/blogs.bmj.com\/bmjopensem\/wp-json\/wp\/v2\/comments?post=134"}],"version-history":[{"count":0,"href":"https:\/\/blogs.bmj.com\/bmjopensem\/wp-json\/wp\/v2\/posts\/134\/revisions"}],"wp:attachment":[{"href":"https:\/\/blogs.bmj.com\/bmjopensem\/wp-json\/wp\/v2\/media?parent=134"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/blogs.bmj.com\/bmjopensem\/wp-json\/wp\/v2\/categories?post=134"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/blogs.bmj.com\/bmjopensem\/wp-json\/wp\/v2\/tags?post=134"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}