{"id":375,"date":"2013-01-18T16:26:09","date_gmt":"2013-01-18T16:26:09","guid":{"rendered":"https:\/\/blogs.bmj.com\/bmjopen\/?p=375"},"modified":"2013-02-27T13:46:18","modified_gmt":"2013-02-27T13:46:18","slug":"using-the-spirit-statement-to-improve-trial-protocols","status":"publish","type":"post","link":"https:\/\/blogs.bmj.com\/bmjopen\/2013\/01\/18\/using-the-spirit-statement-to-improve-trial-protocols\/","title":{"rendered":"Using the SPIRIT statement to improve trial protocols"},"content":{"rendered":"


\nWe have updated our instructions for authors <\/a>to show that we now encourage the use of the SPIRIT statement<\/a>.<\/span><\/span><\/p>\n

SPIRIT (Standard Protocol Items: Recommendations for Interventional Trials) is \u2018an international initiative that aims to improve the quality of clinical trial protocols by defining an evidence-based set of items to address in a protocol\u2019. Its creation was funded by four Canadian health research institutions. <\/span><\/span><\/p>\n

The full statement <\/a>has been published in the Annals of Internal Medicine, and the explanation and elaboration<\/a> in the BMJ. BMJ Open\u2019s editor-in-chief, Dr Trish Groves, is a member of the SPIRIT group. <\/span><\/p>\n

BMJ Open published 17 protocols in 2011 and 79 in 2012, though not all were for interventional trials. We require ethics approval and registration in an ICMJE-approved registry for trial protocols, and encourage registration of systematic review protocols in PROSPERO<\/a>, led by BMJ Open editorial board member Prof Lesley Stewart.<\/span><\/p>\n

Publishing protocols provides a valuable service by allowing researchers to publicise ongoing work and hopefully facilitating cooperation and reducing duplicated efforts. By making the intended methods fully available the chances of a study\u2019s replication may be enhanced. Protocol publication should also ensure that any changes to methods adopted during a trial are reported as such in results papers. <\/span><\/p>\n

As the SPIRIT authors write<\/a>, ‘High quality protocols facilitate proper conduct, reporting, and external review of clinical trials.’\u00a0We will be encouraging authors to use SPIRIT to help meet these goals. <\/span><\/p>\n","protected":false},"excerpt":{"rendered":"

We have updated our instructions for authors to show that we now encourage the use of the SPIRIT statement. SPIRIT (Standard Protocol Items: Recommendations for Interventional Trials) is \u2018an international initiative that aims to improve the quality of clinical trial protocols by defining an evidence-based set of items to address in a protocol\u2019. Its creation […]<\/p>\n

Read More…<\/a><\/p>\n","protected":false},"author":143,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1750,2470,344],"tags":[],"class_list":["post-375","post","type-post","status-publish","format-standard","hentry","category-about-the-journal","category-content","category-journalology"],"yoast_head":"\nUsing the SPIRIT statement to improve trial protocols - BMJ Open<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/blogs.bmj.com\/bmjopen\/2013\/01\/18\/using-the-spirit-statement-to-improve-trial-protocols\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Using the SPIRIT statement to improve trial protocols - BMJ Open\" \/>\n<meta property=\"og:description\" content=\"We have updated our instructions for authors to show that we now encourage the use of the SPIRIT statement. 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