{"id":1745,"date":"2022-10-03T15:56:17","date_gmt":"2022-10-03T15:56:17","guid":{"rendered":"https:\/\/blogs.bmj.com\/bmjopen\/?p=1745"},"modified":"2022-10-18T13:19:44","modified_gmt":"2022-10-18T13:19:44","slug":"top-10-most-read-in-august-glucocorticoid-use-and-brain-structure-identifying-covid-19-with-wearable-sensors-and-alcohol-consumption-after-minimum-unit-pricing","status":"publish","type":"post","link":"https:\/\/blogs.bmj.com\/bmjopen\/2022\/10\/03\/top-10-most-read-in-august-glucocorticoid-use-and-brain-structure-identifying-covid-19-with-wearable-sensors-and-alcohol-consumption-after-minimum-unit-pricing\/","title":{"rendered":"Top 10 most read in August: glucocorticoid use and brain structure, identifying COVID-19 with wearable sensors, and alcohol consumption after minimum unit pricing"},"content":{"rendered":"<figure id=\"attachment_1746\" aria-describedby=\"caption-attachment-1746\" style=\"width: 293px\" class=\"wp-caption alignnone\"><a href=\"https:\/\/blogs.bmj.com\/bmjopen\/files\/2022\/10\/money-5951315_960_720.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-1746 size-medium\" src=\"https:\/\/blogs.bmj.com\/bmjopen\/files\/2022\/10\/money-5951315_960_720-e1664812361464-293x300.jpg\" alt=\"image of coins\" width=\"293\" height=\"300\" srcset=\"https:\/\/blogs.bmj.com\/bmjopen\/files\/2022\/10\/money-5951315_960_720-e1664812361464-293x300.jpg 293w, https:\/\/blogs.bmj.com\/bmjopen\/files\/2022\/10\/money-5951315_960_720-e1664812361464.jpg 478w\" sizes=\"auto, (max-width: 293px) 100vw, 293px\" \/><\/a><figcaption id=\"caption-attachment-1746\" class=\"wp-caption-text\"><span style=\"color: #999999\">Pixabay<\/span><\/figcaption><\/figure>\n<p>Earlier in the year COVID-19 papers were still dominating our top ten chart, but in August the list included a range of topics. Three new additions to the list have been highlighted below.<\/p>\n<p><strong>Association between glucocorticoid use and brain structure<\/strong><\/p>\n<p>At number three in the chart we have Van der Meulen <em>et al.\u00a0<\/em>with a <a href=\"https:\/\/bmjopen.bmj.com\/content\/12\/8\/e062446\">prospective cohort study<\/a> using data from the <a href=\"https:\/\/www.ukbiobank.ac.uk\/\">UK Biobank<\/a>. They investigated whether Glucocorticoid use causes changes in the grey matter volume and white matter microstructure in the brain. Glucocorticoids are immunosuppressive drugs with a range of reported side effects including neuropsychiatric side effects. Van der Meulen <em>et al.\u00a0<\/em>found that Glucocorticoid use was associated with decreased white matter integrity and changes to grey matter volume, they concluded that the changes in brain structure &#8220;may contribute to the neuropsychiatric side effects of glucocorticoid medication&#8221;. However, they were not able to investigate whether there were any dose- or duration-dependent associations of Glucocorticoid use as these data were not available in the UK Biobank.<\/p>\n<p><strong>Machine learning based identification of COVID-19 infection using wearable devices\u00a0<\/strong><\/p>\n<p>Risch\u00a0<em>et al\u00a0<\/em>are at number five in the chart with a <a href=\"https:\/\/bmjopen.bmj.com\/content\/12\/6\/e058274\">prospective cohort study<\/a> to investigate whether presymptomatic COVID-19 can be identified using a wearable sensor bracelet. The ava-bracelet measured five physiological parameters, including respiratory rate and heart rate. A machine-learning algorithm was developed by Risch <em>et al<\/em> to identify COVID-19 infection based on the physiological changes measured by the bracelet. They found that we may be able to identify COVID-19 infection before symptom onset using wearable devices. They did acknowledge that the limited sample means that the study may lack generalisability.<\/p>\n<p><strong>Impact of minimum unit pricing on alcohol consumption in Scotland<\/strong><\/p>\n<p>At number nine is Rehm <em>et al\u00a0<\/em>with a <a href=\"https:\/\/bmjopen.bmj.com\/content\/12\/7\/e054161\">controlled interrupted time series analysis<\/a> investigating whether the introduction of minimum unit pricing impacted alcohol consumption. In 2018 a minimum price of 50p per unit of alcohol was introduced with the aim of reducing harmful alcohol consumption. Rehm\u00a0<em>et al\u00a0<\/em>used &#8220;drink diary&#8221; data to assess consumption levels, where participants retrospectively share how much alcohol they have drunk over the previous week. They found that the introduction of the minimum unit pricing was associated with a reduction in alcohol consumption and that a greater reduction in consumption was found in women than in men. Lower reductions in alcohol consumption were seen in young men and people living in deprived areas. However, alcohol consumption may have been inaccurately estimated by those who were surveyed as the data was collected retrospectively.<\/p>\n<p>Below is the full list of papers that were the most read in\u00a0<i>BMJ Open<\/i> during August 2022.<\/p>\n<table>\n<tbody>\n<tr>\n<td width=\"56\">Rank<\/td>\n<td width=\"180\">Author(s)<\/td>\n<td width=\"365\">Title<\/td>\n<\/tr>\n<tr>\n<td width=\"56\">1<\/td>\n<td width=\"180\">Zemedikun et al.<\/td>\n<td width=\"365\"><a href=\"https:\/\/bmjopen.bmj.com\/content\/11\/12\/e048296\">Burden of chronic diseases associated with periodontal diseases: a retrospective cohort study using UK primary care data<\/a><\/td>\n<\/tr>\n<tr>\n<td width=\"56\">2<\/td>\n<td width=\"180\">Bergeron-Boucher et al.<\/td>\n<td width=\"365\">\n<div class=\"highwire-cite-title\"><a href=\"https:\/\/bmjopen.bmj.com\/content\/12\/8\/e059964\">Probability of males to outlive females: an international comparison from 1751 to 2020<\/a><\/div>\n<\/td>\n<\/tr>\n<tr>\n<td width=\"56\">3<\/td>\n<td width=\"180\">Van der Meulen et al.<\/td>\n<td width=\"365\"><a href=\"https:\/\/bmjopen.bmj.com\/content\/12\/8\/e062446\">Association between use of systemic and inhaled glucocorticoids and changes in brain volume and white matter microstructure: a cross-sectional study using data from the UK Biobank<\/a><\/td>\n<\/tr>\n<tr>\n<td width=\"56\">4<\/td>\n<td width=\"180\">Loohuis et al.<\/td>\n<td width=\"365\"><a href=\"https:\/\/bmjopen.bmj.com\/content\/12\/7\/e051827\">Prediction model study focusing on eHealth in the management of urinary incontinence: the Personalised Advantage Index as a decision-making aid<\/a><\/td>\n<\/tr>\n<tr>\n<td width=\"56\">5<\/td>\n<td width=\"180\">Risch et al.<\/td>\n<td width=\"365\">\n<div class=\"panel-pane pane-highwire-article-citation col-mobile-10 col-narrow-10 col-normal-11 article-title\">\n<div class=\"pane-content\">\n<div id=\"node249532--22003120917\" class=\"highwire-article-citation highwire-citation-type-highwire-article node249532\" data-node-nid=\"249532\" data-pisa=\"bmjopen;12\/6\/e058274\" data-pisa-master=\"bmjopen;bmjopen-2021-058274\" data-apath=\"\/bmjopen\/12\/6\/e058274.atom\">\n<div class=\"highwire-cite-title\"><a href=\"https:\/\/bmjopen.bmj.com\/content\/12\/6\/e058274\">Investigation of the use of a sensor bracelet for the presymptomatic detection of changes in physiological parameters related to COVID-19: an interim analysis of a prospective cohort study (COVI-GAPP)<\/a><\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/td>\n<\/tr>\n<tr>\n<td width=\"56\">6<\/td>\n<td width=\"180\">Osanlou et al.<\/td>\n<td width=\"365\"><a href=\"https:\/\/bmjopen.bmj.com\/content\/12\/7\/e055551\">Adverse drug reactions, multimorbidity and polypharmacy: a prospective analysis of 1 month of medical admissions<\/a><\/td>\n<\/tr>\n<tr>\n<td width=\"56\">7<\/td>\n<td width=\"180\">Fukuma et al.<\/td>\n<td width=\"365\">\n<div class=\"highwire-cite-title\"><a href=\"https:\/\/bmjopen.bmj.com\/content\/12\/7\/e056996\">Impact of the national health guidance intervention for obesity and cardiovascular risks on healthcare utilisation and healthcare spending in working-age Japanese cohort: regression discontinuity design<\/a><\/div>\n<\/td>\n<\/tr>\n<tr>\n<td width=\"56\">8<\/td>\n<td width=\"180\">Burns et al.<\/td>\n<td width=\"365\"><a href=\"https:\/\/bmjopen.bmj.com\/content\/12\/7\/e056517\">Systematic review and meta-analysis to examine intrapartum interventions, and maternal and neonatal outcomes following immersion in water during labour and waterbirth<\/a><\/td>\n<\/tr>\n<tr>\n<td width=\"56\">9<\/td>\n<td width=\"180\">Rehm et al.<\/td>\n<td width=\"365\"><a href=\"https:\/\/bmjopen.bmj.com\/content\/12\/7\/e054161\">Differential impact of minimum unit pricing on alcohol consumption between Scottish men and women: controlled interrupted time series analysis<\/a><\/td>\n<\/tr>\n<tr>\n<td width=\"56\">10<\/td>\n<td width=\"180\">Walach et al.<\/td>\n<td width=\"365\"><a href=\"https:\/\/bmjopen.bmj.com\/content\/12\/8\/e060555\">Why do people consent to receiving SARS-CoV-2 vaccinations? A representative survey in Germany<\/a><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p><em>Most read figures are based on pdf downloads and full text views. Abstract views are excluded.<\/em><\/p>\n<p>Like what you see? Follow <a href=\"https:\/\/bmjopen.bmj.com\/content\/12\/10?current-issue=y\">this link<\/a> to see our most recent content<!--TrendMD v2.4.8--><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Earlier in the year COVID-19 papers were still dominating our top ten chart, but in August the list included a range of topics. Three new additions to the list have been highlighted below. Association between glucocorticoid use and brain structure At number three in the chart we have Van der Meulen et al.\u00a0with a prospective [&#8230;]<\/p>\n<p><a class=\"btn btn-secondary understrap-read-more-link\" href=\"https:\/\/blogs.bmj.com\/bmjopen\/2022\/10\/03\/top-10-most-read-in-august-glucocorticoid-use-and-brain-structure-identifying-covid-19-with-wearable-sensors-and-alcohol-consumption-after-minimum-unit-pricing\/\">Read More&#8230;<\/a><\/p>\n","protected":false},"author":430,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[2471],"tags":[],"class_list":["post-1745","post","type-post","status-publish","format-standard","hentry","category-highly-accessed"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.5 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Top 10 most read in August: glucocorticoid use and brain structure, identifying COVID-19 with wearable sensors, and alcohol consumption after minimum unit pricing - BMJ Open<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/blogs.bmj.com\/bmjopen\/2022\/10\/03\/top-10-most-read-in-august-glucocorticoid-use-and-brain-structure-identifying-covid-19-with-wearable-sensors-and-alcohol-consumption-after-minimum-unit-pricing\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Top 10 most read in August: glucocorticoid use and brain structure, identifying COVID-19 with wearable sensors, and alcohol consumption after minimum unit pricing - BMJ Open\" \/>\n<meta property=\"og:description\" content=\"Earlier in the year COVID-19 papers were still dominating our top ten chart, but in August the list included a range of topics. 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