{"id":1227,"date":"2018-01-23T23:32:56","date_gmt":"2018-01-23T23:32:56","guid":{"rendered":"https:\/\/blogs.bmj.com\/bmjopen\/?p=1227"},"modified":"2018-01-23T16:28:18","modified_gmt":"2018-01-23T16:28:18","slug":"women-taking-probiotics-during-pregnancy-might-have-lower-pre-eclampsia-and-premature-birth-risk","status":"publish","type":"post","link":"https:\/\/blogs.bmj.com\/bmjopen\/2018\/01\/23\/women-taking-probiotics-during-pregnancy-might-have-lower-pre-eclampsia-and-premature-birth-risk\/","title":{"rendered":"Women taking probiotics during pregnancy might have lower pre-eclampsia and premature birth risk"},"content":{"rendered":"<p><em>But timing may be crucial, findings suggest<\/em><\/p>\n<p dir=\"ltr\"><span id=\"m_-7110143273580166783gmail-m_6022578362215513292docs-internal-guid-b8365f4a-0e87-7440-7278-05b4a532615d\"><a href=\"http:\/\/bmjopen.bmj.com\/lookup\/doi\/10.1136\/bmjopen-2017-018021\">Probiotics taken during pregnancy might help lower the risks of pre-eclampsia and premature birth, suggests observational research<\/a> in the online journal <em><a href=\"http:\/\/bmjopen.bmj.com\/\"><strong>BMJ Open<\/strong><\/a>.\u00a0<\/em>But timing may be crucial, the findings indicate.<\/span><\/p>\n<p dir=\"ltr\"><span id=\"m_-7110143273580166783gmail-m_6022578362215513292docs-internal-guid-b8365f4a-0e87-7440-7278-05b4a532615d\">Pre-eclampsia, a condition in which the mother\u2019s body mounts an exaggerated inflammatory response, affects up to 8 percent of all pregnancies, and can lead to severe complications for both mother and baby. <\/span><\/p>\n<p dir=\"ltr\"><span id=\"m_-7110143273580166783gmail-m_6022578362215513292docs-internal-guid-b8365f4a-0e87-7440-7278-05b4a532615d\">Premature birth (before 37 weeks) is a leading cause of illness and disability among the children born, affecting nearly one in 10 births in the US.<\/span><\/p>\n<p dir=\"ltr\"><span id=\"m_-7110143273580166783gmail-m_6022578362215513292docs-internal-guid-b8365f4a-0e87-7440-7278-05b4a532615d\">A growing body of evidence suggests that the mother\u2019s diet influences the outcome of pregnancy. And previous research has suggested that probiotics&#8211;live bacteria and yeasts thought to promote good health&#8211;might reduce certain complications of pregnancy.<\/span><\/p>\n<p dir=\"ltr\"><span id=\"m_-7110143273580166783gmail-m_6022578362215513292docs-internal-guid-b8365f4a-0e87-7440-7278-05b4a532615d\">To find out whether the timing of intake might be influential, the researchers used data on more than 70,000 pregnancies from the Norwegian Mother and Child Cohort Study (MoBa).<\/span><\/p>\n<p dir=\"ltr\"><span id=\"m_-7110143273580166783gmail-m_6022578362215513292docs-internal-guid-b8365f4a-0e87-7440-7278-05b4a532615d\">As part of the MoBa study, mums-to-be provided information on their diet, lifestyle, medical history, and other relevant background factors at 15, 22, and 30 weeks of pregnancy.<\/span><\/p>\n<p dir=\"ltr\"><span id=\"m_-7110143273580166783gmail-m_6022578362215513292docs-internal-guid-b8365f4a-0e87-7440-7278-05b4a532615d\">At 15 and 30 weeks, the questions included additional information on intake of different milk products containing probiotic bacteria before and during their pregnancy.<\/span><\/p>\n<p dir=\"ltr\"><span id=\"m_-7110143273580166783gmail-m_6022578362215513292docs-internal-guid-b8365f4a-0e87-7440-7278-05b4a532615d\">Nearly one in four (just over 23%; 6502) women said they had consumed probiotic milk products before their pregnancy; more than a third (over 37%; 11,221) had done so during early pregnancy; and a similar proportion (just over 32%; 12,784) had done so late on.<\/span><\/p>\n<p dir=\"ltr\"><span id=\"m_-7110143273580166783gmail-m_6022578362215513292docs-internal-guid-b8365f4a-0e87-7440-7278-05b4a532615d\">Intake of probiotic milk products was more common among older, more affluent and better educated women, who were pregnant for the first time.<\/span><\/p>\n<p dir=\"ltr\"><span id=\"m_-7110143273580166783gmail-m_6022578362215513292docs-internal-guid-b8365f4a-0e87-7440-7278-05b4a532615d\">Among the 37,050 women included in the pre-eclampsia analysis, the condition was diagnosed in one in 20 (5%; 1851). In 550 of these cases, it was severe. Probiotic intake was associated with a 20 percent lower risk of the condition, but only during late pregnancy. <\/span><\/p>\n<p dir=\"ltr\"><span id=\"m_-7110143273580166783gmail-m_6022578362215513292docs-internal-guid-b8365f4a-0e87-7440-7278-05b4a532615d\">And when differences between the severity of pre-eclampsia were looked at separately this association was significant only for those whose condition was severe.<\/span><\/p>\n<p dir=\"ltr\"><span id=\"m_-7110143273580166783gmail-m_6022578362215513292docs-internal-guid-b8365f4a-0e87-7440-7278-05b4a532615d\">Among the 34,458 women included in the premature birth analysis, 2858 babies were born early, some 1795 of which were spontaneous premature births, and 1065 of which were iatrogenic&#8211;in other words, caused by the consequences of medical treatment.<\/span><\/p>\n<p dir=\"ltr\"><span id=\"m_-7110143273580166783gmail-m_6022578362215513292docs-internal-guid-b8365f4a-0e87-7440-7278-05b4a532615d\">A significant association emerged between probiotic intake during early pregnancy and an 11 percent lower risk of premature birth, rising to 27 percent for preterm birth late in the pregnancy.<\/span><\/p>\n<p dir=\"ltr\"><span id=\"m_-7110143273580166783gmail-m_6022578362215513292docs-internal-guid-b8365f4a-0e87-7440-7278-05b4a532615d\">The amount of probiotic consumed didn\u2019t seem to make any difference, the findings showed.<\/span><\/p>\n<p dir=\"ltr\"><span id=\"m_-7110143273580166783gmail-m_6022578362215513292docs-internal-guid-b8365f4a-0e87-7440-7278-05b4a532615d\">This is an observational study, so no firm conclusions can be drawn about cause and effect, nor were the researchers able to account for strain viability or shelf life, \u00a0both of which may have influenced the findings. Further research is required, they emphasise. <\/span><\/p>\n<p dir=\"ltr\"><span id=\"m_-7110143273580166783gmail-m_6022578362215513292docs-internal-guid-b8365f4a-0e87-7440-7278-05b4a532615d\">Nevertheless, they conclude: \u201cIf future randomised controlled studies support a protective effect of probiotic consumption on reduced risk of pre-eclampsia and preterm delivery, recommending [it] would be a promising public health measure to prevent these adverse pregnancy outcomes.\u201d<\/span><\/p>\n<p><!--TrendMD v2.4.8--><\/p>\n","protected":false},"excerpt":{"rendered":"<p>But timing may be crucial, findings suggest Probiotics taken during pregnancy might help lower the risks of pre-eclampsia and premature birth, suggests observational research in the online journal BMJ Open.\u00a0But timing may be crucial, the findings indicate. Pre-eclampsia, a condition in which the mother\u2019s body mounts an exaggerated inflammatory response, affects up to 8 percent [&#8230;]<\/p>\n<p><a class=\"btn btn-secondary understrap-read-more-link\" href=\"https:\/\/blogs.bmj.com\/bmjopen\/2018\/01\/23\/women-taking-probiotics-during-pregnancy-might-have-lower-pre-eclampsia-and-premature-birth-risk\/\">Read More&#8230;<\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[2470,511],"tags":[],"class_list":["post-1227","post","type-post","status-publish","format-standard","hentry","category-content","category-in-the-news"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.4 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Women taking probiotics during pregnancy might have lower pre-eclampsia and premature birth risk - BMJ Open<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/blogs.bmj.com\/bmjopen\/2018\/01\/23\/women-taking-probiotics-during-pregnancy-might-have-lower-pre-eclampsia-and-premature-birth-risk\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Women taking probiotics during pregnancy might have lower pre-eclampsia and premature birth risk - BMJ Open\" \/>\n<meta property=\"og:description\" content=\"But timing may be crucial, findings suggest Probiotics taken during pregnancy might help lower the risks of pre-eclampsia and premature birth, suggests observational research in the online journal BMJ Open.\u00a0But timing may be crucial, the findings indicate. 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