{"id":2247,"date":"2021-04-20T11:08:44","date_gmt":"2021-04-20T11:08:44","guid":{"rendered":"https:\/\/blogs.bmj.com\/bmjebmspotlight\/?p=2247"},"modified":"2021-06-10T09:30:41","modified_gmt":"2021-06-10T09:30:41","slug":"missing-data-only-half-of-depression-treatment-studies-in-the-u-s-report-their-results","status":"publish","type":"post","link":"https:\/\/blogs.bmj.com\/bmjebmspotlight\/2021\/04\/20\/missing-data-only-half-of-depression-treatment-studies-in-the-u-s-report-their-results\/","title":{"rendered":"Missing Data? – Only Half of Depression Treatment Studies in the U.S. Report Their Results"},"content":{"rendered":"

Blog entry written on:<\/span> Transparency of Results Reporting for Depression Treatment Studies in ClinicalTrials.gov: A Cross-Sectional Study<\/em><\/a>, <\/span>(bmjebm-2020-111641.R2)<\/span><\/p>\n

Authors: Karen B Schmaling, Hailey S Landon, Tiffany B Nguyen, Robert M Kaplan<\/em><\/p>\n

\n

Depression is a common condition that is treated by psychotherapies, medications, and procedures. A comprehensive picture of how well these treatments work — based on published and unpublished studies \u2013 is needed to guide research and practice.<\/p>\n

We examined 725 depression treatment studies conducted in the U.S. between 2008 and 2019 and listed in the ClinicalTrials.gov registration system. Only 57% of the studies posted any results. Half (52%) of studies that did not post results were required to do so by U.S. law.<\/p>\n

Studies with results posted in ClinicalTrials.gov were more likely to have publications from the study; to have specified hypotheses; and to have medication treatment conditions.<\/p>\n

The purpose of mandatory study registration and outcome reporting is to increase transparent information sharing. We don\u2019t know why results were not posted, but clearer standards and contingencies \u2013 such as trial registry reports being a precondition for journal publication \u2013 might increase reporting and lead to more complete information about depression treatment results.<\/p>\n

Title: Transparency of results reporting for depression treatment studies in ClinicalTrials.gov: A cross-sectional study. doi:10.1136\/bmjebm-111641 (bmjebm-2020-111641.R2).<\/p>\n

\"Puzzle<\/a><\/p>\n

\n

Authors<\/strong><\/p>\n

Karen B. Schmaling<\/p>\n

\"Image<\/a><\/p>\n

Washington State University
\nConflict of interest disclosures:<\/strong> None.<\/p>\n

Hailey S. Landon<\/p>\n

\"Image<\/a><\/p>\n

Washington State University
\nConflict of interest disclosures:<\/strong> None.<\/p>\n

Tiffany B. Nguyen<\/p>\n

\"Image<\/a><\/p>\n

Washington State University
\nConflict of interest disclosures:<\/strong> None.<\/p>\n

Robert M. Kaplan<\/p>\n

\"Image<\/a><\/p>\n

Stanford University
\nConflict of interest disclosures:<\/strong> None.<\/p>\n

\n

DISCLAIMER<\/b><\/p>\n

The views and opinions expressed on this site are solely those of the original authors. They do not necessarily represent the views of the BMJ and should not be used to replace medical advice. All information on this blog is for general information, is not peer-reviewed, requires checking with original sources and should not be used to make any decisions about healthcare. No responsibility for its accuracy and correctness is assumed by us, and we disclaim all liability and responsibility arising from any reliance placed on such commentary or content by any user or visitor to the Website, or by anyone who may be informed of any of its content. Any reliance you place on the material posted on this site is therefore strictly at your own risk.<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"

Blog entry written on: Transparency of Results Reporting for Depression Treatment Studies in ClinicalTrials.gov: A Cross-Sectional Study, (bmjebm-2020-111641.R2) Authors: Karen B Schmaling, Hailey S Landon, Tiffany B Nguyen, Robert M Kaplan Depression is a common condition that is treated by psychotherapies, medications, and procedures. A comprehensive picture of how well these treatments work — based […]<\/p>\n

Read More…<\/a><\/p>\n","protected":false},"author":405,"featured_media":2248,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[14375,14432,14351],"tags":[],"class_list":["post-2247","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-bmj-ebm-spotlight","category-clinical-trials","category-ebm"],"yoast_head":"\nMissing Data? - Only Half of Depression Treatment Studies in the U.S. Report Their Results - BMJ EBM Spotlight<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/blogs.bmj.com\/bmjebmspotlight\/2021\/04\/20\/missing-data-only-half-of-depression-treatment-studies-in-the-u-s-report-their-results\/\" \/>\n<meta property=\"og:locale\" content=\"en_GB\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Missing Data? - Only Half of Depression Treatment Studies in the U.S. Report Their Results - BMJ EBM Spotlight\" \/>\n<meta property=\"og:description\" content=\"Blog entry written on: Transparency of Results Reporting for Depression Treatment Studies in ClinicalTrials.gov: A Cross-Sectional Study, (bmjebm-2020-111641.R2) Authors: Karen B Schmaling, Hailey S Landon, Tiffany B Nguyen, Robert M Kaplan Depression is a common condition that is treated by psychotherapies, medications, and procedures. 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