{"id":2190,"date":"2020-11-18T10:32:58","date_gmt":"2020-11-18T10:32:58","guid":{"rendered":"https:\/\/blogs.bmj.com\/bmjebmspotlight\/?p=2190"},"modified":"2020-11-18T11:21:20","modified_gmt":"2020-11-18T11:21:20","slug":"seeing-is-believing-blinding-practices-during-point-of-care-ultrasound-research","status":"publish","type":"post","link":"https:\/\/blogs.bmj.com\/bmjebmspotlight\/2020\/11\/18\/seeing-is-believing-blinding-practices-during-point-of-care-ultrasound-research\/","title":{"rendered":"Seeing is believing: blinding practices during point-of-care ultrasound research"},"content":{"rendered":"<p>Blog entry written on: <a href=\"https:\/\/ebm.bmj.com\/content\/early\/2020\/11\/11\/bmjebm-2020-111577\"><em>Blinding practices during acute point-of-care ultrasound research: the BLIND-US meta-research study<\/em><\/a>, (bmjebm-2020-111577)<\/p>\n<p><em>Authors: Ross Prager, Kay Wu2, Roudi Bachar, Rudy R Unni, Joshua Bowdridge, Trevor A McGrath, Rajiv Thavanathan, Michael Y Woo, Matthew D F McInnes<\/em><\/p>\n<hr \/>\n<p>Point of care ultrasound (POCUS) has become an invaluable tool for many clinicians. As the evidence supporting its integration into clinical practice grows, a critical look at research practices is important to ensure decisions are being made with the highest quality evidence possible.<\/p>\n<p>One aspect of diagnostic accuracy study design that may impact generalizability and risk of bias are blinding practices. Whereas blinding of the POCUS interpreter to the reference stands (and vice versa) is as an important step to limit bias, whether the person performing the POCUS scan should be blinded to the patient\u2019s clinical information is less clear. The objective of our study was to characterize blinding practices during acute POCUS research.<\/p>\n<p>In our study \u201cBlinding practices during acute point-of-care ultrasound research: the BLIND-US meta-research study\u201d (bmjebm-2020-111577), we searched the acute POCUS literature for studies assessing the diagnostic accuracy of POCUS. We identified 97 studies meeting the inclusion criteria. We found that the POCUS interpreter was blinded to clinical information in 37 studies (38.1%), not blinded in 34 studies (35.1%), and not reported in 26 studies (26.8%). The POCUS interpreter was the same person obtaining the images in 72 studies (74.2%), different in 14 studies (14.4%), and not reported in 11 studies (11.3%).<\/p>\n<p>This significant variation in blinding practices is important to discuss. We would argue that blinding the POCUS interpreter to clinical information places the test outside of its routine clinical use. This may limit generalizability, applicability, and ultimately accurate translation of research into practice. This means that for clinicians reading POCUS studies, attention to the blinding practices is important to ensure the results are generalizable. For researchers designing POCUS studies, we recommend that POCUS interpreters not be blinded to the clinical information, as blinding to clinical information is not reflective of the routine clinical use of POCUS. Additionally, researchers should consider reporting incremental diagnostic yield (how much additional accuracy a test provides in an existing diagnostic pathway) or assessing other patient centered outcomes. These study designs move beyond the question of whether POCUS <em>can<\/em> be performed, to whether POCUS <em>should <\/em>be performed for a specific indication.<\/p>\n<p><a href=\"https:\/\/blogs.bmj.com\/bmjebmspotlight\/files\/2020\/11\/eye.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\" wp-image-2191\" src=\"https:\/\/blogs.bmj.com\/bmjebmspotlight\/files\/2020\/11\/eye.jpg\" alt=\"Brown eye\" width=\"344\" height=\"249\" \/><\/a><\/p>\n<hr \/>\n<p><strong>Author<\/strong><br \/>\nRoss Prager, MD<br \/>\nInternal Medicine Resident<br \/>\nUniversity of Ottawa<\/p>\n<p><a href=\"https:\/\/blogs.bmj.com\/bmjebmspotlight\/files\/2020\/11\/Ross-Prager-SOCIAL-MEDIA-V.2.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"size-medium wp-image-2193\" src=\"https:\/\/blogs.bmj.com\/bmjebmspotlight\/files\/2020\/11\/Ross-Prager-SOCIAL-MEDIA-V.2-214x300.jpg\" alt=\"Image of author\" width=\"214\" height=\"300\" srcset=\"https:\/\/blogs.bmj.com\/bmjebmspotlight\/files\/2020\/11\/Ross-Prager-SOCIAL-MEDIA-V.2-214x300.jpg 214w, https:\/\/blogs.bmj.com\/bmjebmspotlight\/files\/2020\/11\/Ross-Prager-SOCIAL-MEDIA-V.2-731x1024.jpg 731w, https:\/\/blogs.bmj.com\/bmjebmspotlight\/files\/2020\/11\/Ross-Prager-SOCIAL-MEDIA-V.2-768x1075.jpg 768w, https:\/\/blogs.bmj.com\/bmjebmspotlight\/files\/2020\/11\/Ross-Prager-SOCIAL-MEDIA-V.2-1097x1536.jpg 1097w, https:\/\/blogs.bmj.com\/bmjebmspotlight\/files\/2020\/11\/Ross-Prager-SOCIAL-MEDIA-V.2-1463x2048.jpg 1463w, https:\/\/blogs.bmj.com\/bmjebmspotlight\/files\/2020\/11\/Ross-Prager-SOCIAL-MEDIA-V.2-640x896.jpg 640w, https:\/\/blogs.bmj.com\/bmjebmspotlight\/files\/2020\/11\/Ross-Prager-SOCIAL-MEDIA-V.2.jpg 1500w\" sizes=\"auto, (max-width: 214px) 100vw, 214px\" \/><\/a><\/p>\n<p>Ross Prager has no conflict of interest to declare<\/p>\n<hr \/>\n<p><b>DISCLAIMER<\/b><\/p>\n<p><span style=\"font-weight: 400\">The views and opinions expressed on this site are solely those of the original authors. They do not necessarily represent the views of the BMJ and should not be used to replace medical advice. All information on this blog is for general information, is not peer-reviewed, requires checking with original sources and should not be used to make any decisions about healthcare. No responsibility for its accuracy and correctness is assumed by us, and we disclaim all liability and responsibility arising from any reliance placed on such commentary or content by any user or visitor to the Website, or by anyone who may be informed of any of its content. Any reliance you place on the material posted on this site is therefore strictly at your own risk.<\/span><!--TrendMD v2.4.8--><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Blog entry written on: Blinding practices during acute point-of-care ultrasound research: the BLIND-US meta-research study, (bmjebm-2020-111577) Authors: Ross Prager, Kay Wu2, Roudi Bachar, Rudy R Unni, Joshua Bowdridge, Trevor A McGrath, Rajiv Thavanathan, Michael Y Woo, Matthew D F McInnes Point of care ultrasound (POCUS) has become an invaluable tool for many clinicians. As the [&#8230;]<\/p>\n<p><a class=\"btn btn-secondary understrap-read-more-link\" href=\"https:\/\/blogs.bmj.com\/bmjebmspotlight\/2020\/11\/18\/seeing-is-believing-blinding-practices-during-point-of-care-ultrasound-research\/\">Read More&#8230;<\/a><\/p>\n","protected":false},"author":405,"featured_media":2157,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[14375,14351,14421],"tags":[],"class_list":["post-2190","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-bmj-ebm-spotlight","category-ebm","category-ultrasound"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.4 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Seeing is believing: blinding practices during point-of-care ultrasound research - BMJ EBM Spotlight<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/blogs.bmj.com\/bmjebmspotlight\/2020\/11\/18\/seeing-is-believing-blinding-practices-during-point-of-care-ultrasound-research\/\" \/>\n<meta property=\"og:locale\" content=\"en_GB\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Seeing is believing: blinding practices during point-of-care ultrasound research - BMJ EBM Spotlight\" \/>\n<meta property=\"og:description\" content=\"Blog entry written on: Blinding practices during acute point-of-care ultrasound research: the BLIND-US meta-research study, (bmjebm-2020-111577) Authors: Ross Prager, Kay Wu2, Roudi Bachar, Rudy R Unni, Joshua Bowdridge, Trevor A McGrath, Rajiv Thavanathan, Michael Y Woo, Matthew D F McInnes Point of care ultrasound (POCUS) has become an invaluable tool for many clinicians. 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