{"id":73,"date":"2006-12-28T12:46:55","date_gmt":"2006-12-28T11:46:55","guid":{"rendered":"http:\/\/resource.bmj.com\/bmj\/2006\/12\/28\/lancet-23-dec-2006\/"},"modified":"2006-12-28T12:46:55","modified_gmt":"2006-12-28T11:46:55","slug":"lancet-23-dec-2006","status":"publish","type":"post","link":"https:\/\/blogs.bmj.com\/bmj\/2006\/12\/28\/lancet-23-dec-2006\/","title":{"rendered":"Lancet 23 Dec 2006"},"content":{"rendered":"<p>2195 How safe is paracetamol? This <a href=\"http:\/\/www.thelancet.com\/journals\/lancet\/article\/PIIS0140673606698747\/fulltext\">editorial <\/a>highlights the study which showed that at therapeutic (4G\/day) doses it can cause ALT elevation in some normal subjects (<a href=\"http:\/\/jama.ama-assn.org\/cgi\/content\/full\/296\/1\/87\"><em>JAMA 2006;<\/em>296:87<\/a>), but I think we need to be a bit more worried about the evidence linking it with asthma exacerbations too.<!--more--><\/p>\n<p>The dreadful <a href=\"http:\/\/www.thelancet.com\/journals\/lancet\/article\/PIIS0140673606698954\/fulltext\">influenza pandemic of 1918-2<\/a>0 continues to haunt us as we look out for its inevitable successor. This <a href=\"http:\/\/www.thelancet.com\/journals\/lancet\/article\/PIIS0140673606698954\/fulltext\">paper <\/a>looks at the information we have about its <a href=\"http:\/\/www.thelancet.com\/journals\/lancet\/article\/PIIS0140673606698954\/fulltext\">epidemiology<\/a>. It differed from other recorded pandemics in its size, virulence, and predilection for killing young adults. The only constant feature of flu plagues is that they tend to kill poor people most.<\/p>\n<p>This <a href=\"http:\/\/www.thelancet.com\/journals\/lancet\/article\/PIIS0140673606698966\/fulltext\">study <\/a>of the response to last year\u2019s London bombings is fairly reassuring; the <a href=\"http:\/\/www.thelancet.com\/journals\/lancet\/article\/PIIS0140673606698966\/fulltext\">surge capacity<\/a> of local hospitals proved adequate, and, contrary to popular myth, the quantity of blood transfused hardly differed from the daily average.<\/p>\n<p>For forty years, people in <a href=\"http:\/\/www.thelancet.com\/journals\/lancet\/article\/PIIS0140673606688958\/fulltext\">Eastern Europe<\/a> led lives which were drab, stultifying, sometimes harsh but usually <a href=\"http:\/\/www.thelancet.com\/journals\/lancet\/article\/PIIS0140673606688958\/fulltext\">safe<\/a>. Now they dash around optimistically but often fall prey to unemployment, cheap alcohol and badly designed traffic systems. Their <a href=\"http:\/\/www.thelancet.com\/journals\/lancet\/article\/PIIS0140673606688958\/fulltext\">accident rates<\/a> are climbing while ours are falling. Will the market bring solutions, or are they dispensable?<\/p>\n","protected":false},"excerpt":{"rendered":"<p>2195 How safe is paracetamol? This editorial highlights the study which showed that at therapeutic (4G\/day) doses it can cause ALT elevation in some normal subjects (JAMA 2006;296:87), but I [&#8230;]<\/p>\n<p><a class=\"btn btn-secondary understrap-read-more-link\" href=\"https:\/\/blogs.bmj.com\/bmj\/2006\/12\/28\/lancet-23-dec-2006\/\">More&#8230;<\/a><\/p>\n","protected":false},"author":1,"featured_media":38363,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[111],"tags":[],"class_list":["post-73","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-richard-lehmans-weekly-review-of-medical-journals"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.4 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Lancet 23 Dec 2006 - The BMJ<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/blogs.bmj.com\/bmj\/2006\/12\/28\/lancet-23-dec-2006\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Lancet 23 Dec 2006 - The BMJ\" \/>\n<meta property=\"og:description\" content=\"2195 How safe is paracetamol? This editorial highlights the study which showed that at therapeutic (4G\/day) doses it can cause ALT elevation in some normal subjects (JAMA 2006;296:87), but I [...]More...\" \/>\n<meta property=\"og:url\" content=\"https:\/\/blogs.bmj.com\/bmj\/2006\/12\/28\/lancet-23-dec-2006\/\" \/>\n<meta property=\"og:site_name\" content=\"The BMJ\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/bmjdotcom\/\" \/>\n<meta property=\"article:published_time\" content=\"2006-12-28T11:46:55+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/blogs.bmj.com\/bmj\/files\/2017\/02\/richard-lehman.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"540\" \/>\n\t<meta property=\"og:image:height\" content=\"350\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"BMJ\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:creator\" content=\"@bmj_latest\" \/>\n<meta name=\"twitter:site\" content=\"@bmj_latest\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"BMJ\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/blogs.bmj.com\\\/bmj\\\/2006\\\/12\\\/28\\\/lancet-23-dec-2006\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/blogs.bmj.com\\\/bmj\\\/2006\\\/12\\\/28\\\/lancet-23-dec-2006\\\/\"},\"author\":{\"name\":\"BMJ\",\"@id\":\"https:\\\/\\\/blogs.bmj.com\\\/bmj\\\/#\\\/schema\\\/person\\\/ba3da426ed20e8f1d933ca367d8216fe\"},\"headline\":\"Lancet 23 Dec 2006\",\"datePublished\":\"2006-12-28T11:46:55+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/blogs.bmj.com\\\/bmj\\\/2006\\\/12\\\/28\\\/lancet-23-dec-2006\\\/\"},\"wordCount\":202,\"commentCount\":0,\"publisher\":{\"@id\":\"https:\\\/\\\/blogs.bmj.com\\\/bmj\\\/#organization\"},\"image\":{\"@id\":\"https:\\\/\\\/blogs.bmj.com\\\/bmj\\\/2006\\\/12\\\/28\\\/lancet-23-dec-2006\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/blogs.bmj.com\\\/bmj\\\/files\\\/2017\\\/02\\\/richard-lehman.jpg\",\"articleSection\":[\"Richard Lehman's weekly review of medical journals\"],\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"CommentAction\",\"name\":\"Comment\",\"target\":[\"https:\\\/\\\/blogs.bmj.com\\\/bmj\\\/2006\\\/12\\\/28\\\/lancet-23-dec-2006\\\/#respond\"]}]},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/blogs.bmj.com\\\/bmj\\\/2006\\\/12\\\/28\\\/lancet-23-dec-2006\\\/\",\"url\":\"https:\\\/\\\/blogs.bmj.com\\\/bmj\\\/2006\\\/12\\\/28\\\/lancet-23-dec-2006\\\/\",\"name\":\"Lancet 23 Dec 2006 - 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