{"id":47274,"date":"2020-04-23T17:42:35","date_gmt":"2020-04-23T16:42:35","guid":{"rendered":"https:\/\/blogs.bmj.com\/bmj\/?p=47274"},"modified":"2020-04-30T11:05:50","modified_gmt":"2020-04-30T10:05:50","slug":"covid-19-and-sub-saharan-africas-critical-care-infrastructure","status":"publish","type":"post","link":"https:\/\/blogs.bmj.com\/bmj\/2020\/04\/23\/covid-19-and-sub-saharan-africas-critical-care-infrastructure\/","title":{"rendered":"Covid-19 and sub-Saharan Africa\u2019s critical care infrastructure"},"content":{"rendered":"<p class=\"standfirst\">The ICU capacity that is critical to managing covid-19 complications is severely limited in much of the region, warn Edgar Asiimwe and Saraswati Kache<\/p>\n<p><!--more--><span style=\"font-weight: 400\">The covid-19 pandemic has undoubtedly challenged our previously held assumptions about global disease epidemiology. Classic public health teaching promulgates the theory of a prevailing epidemiologic transition\u2014one in which the burden of disease morphs from predominantly infectious causes to non-communicable causes as countries industrialize. That theory has now been turned on its head as public health campaigns in industrialized countries promote basic hygiene, while restrictive lockdowns upend regular life. For many, these developments feel like regression to a hitherto forgotten era, with industrialized nations now living the contemporary experience of many in developing countries.<\/span><\/p>\n<p><span style=\"font-weight: 400\">But as industrialized nations grapple with this new reality, scrambling to treat the sudden rush of patients,<br \/>\nsub-Saharan Africa watches nervously from the sidelines\u2014covid-19\u2019s impact there would be catastrophic at best. It\u2019s easy to see why: the <\/span><a href=\"https:\/\/jamanetwork.com\/journals\/jama\/fullarticle\/2763188\"><span style=\"font-weight: 400\">ICU capacity that is critical<\/span><\/a><span style=\"font-weight: 400\"> to managing covid-19 complications is severely limited in much of the region. In Uganda, for example, it\u2019s been reported that there are only <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/31715537\">55 functional ICU beds<\/a> for a population of around 40 million people. Neighboring <\/span><span style=\"font-weight: 400\"><a href=\"http:\/\/rwandatoday.africa\/news\/Covid-19-puts-hospitals-on-alert\/4383214-5490102-9ne2b4\/index.html\">Rwanda has an estimated 50<\/a> for a population of 12 million<\/span><span style=\"font-weight: 400\">, <\/span><span style=\"font-weight: 400\"><a href=\"https:\/\/journals.plos.org\/plosone\/article?id=10.1371\/journal.pone.0224355\">Tanzania has 38<\/a> for a population of 58 million, <\/span>while <span style=\"font-weight: 400\"><a href=\"https:\/\/www.cnn.com\/2020\/04\/18\/africa\/covid-19-ventilator-shortage-intl-scli\/index.html\">South Sudan has 24 beds<\/a> for a population of 12 million.<\/span><\/p>\n<p><span style=\"font-weight: 400\">The significant burden of HIV among young people in the region, which is likely to leave them more vulnerable to complications, has also caused the World Health Organization to raise concerns about <\/span><a href=\"https:\/\/socialsciences.nature.com\/users\/297007-charlottte-payne\/posts\/63676-covid-19-in-africa\"><span style=\"font-weight: 400\">a potential difference in mortality demographics<\/span><\/a><span style=\"font-weight: 400\"> between the countries that have been worst hit so far and sub-Saharan Africa. As a result, an outbreak there could negatively impact Africa\u2019s demographic dividend.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400\">Aware of these risks, many countries in the region have <\/span><a href=\"https:\/\/www.brookings.edu\/blog\/africa-in-focus\/2020\/04\/04\/africa-in-the-news-impacts-of-covid-19-on-african-economies-and-elections-updates\/\"><span style=\"font-weight: 400\">imposed aggressive containment interventions, closing schools and shutting borders<\/span><\/a><span style=\"font-weight: 400\">. Yet despite these measures, there has been <\/span><a href=\"https:\/\/www.mckinsey.com\/featured-insights\/middle-east-and-africa\/tackling-covid-19-in-africa\"><span style=\"font-weight: 400\">a slow, albeit unrelenting, uptick<\/span><\/a><span style=\"font-weight: 400\"> in confirmed cases, causing increased anxiety about an impending onslaught. Containment measures have also dealt massive collateral economic damage, further impoverishing many in central and west Africa, where <\/span><a href=\"https:\/\/www.cgdev.org\/blog\/economic-impact-covid-19-africa-weeks-latest-analysis\"><span style=\"font-weight: 400\">over 80% of the rural population<\/span><\/a><span style=\"font-weight: 400\"> relies on seasonal and irregular work.<\/span><\/p>\n<p><span style=\"font-weight: 400\">But why is sub-Saharan Africa\u2019s critical care capacity so unprepared for this pandemic? At first glance, the reasons are similar to those seen in developed countries: critical care medicine is expensive. In much of<br \/>\nsub-Saharan Africa, as with other low and middle income countries, limited resources are an impediment to investment in critical care, a factor that often necessitates a utilitarian approach to healthcare spending. That approach invariably favors spending on the most prevalent infectious diseases, while neglecting other sectors in the health system. <\/span><\/p>\n<p><span style=\"font-weight: 400\">The strategy has worked thus far: <\/span><a href=\"https:\/\/www.statista.com\/statistics\/805644\/life-expectancy-at-birth-in-sub-saharan-africa\/\"><span style=\"font-weight: 400\">life expectancy has broadly improved<\/span><\/a><span style=\"font-weight: 400\"> in the region over the past two decades. But this specialization has left countries vulnerable to unpredictable health events, like covid-19, which can cause unfathomable loss of life and economic destruction.\u00a0<\/span><span style=\"font-weight: 400\">To illustrate, McKinsey now predicts that<br \/>\nsub-Saharan Africa\u2019s economies could lose <\/span><a href=\"https:\/\/www.worldbank.org\/en\/region\/afr\/publication\/for-sub-saharan-africa-coronavirus-crisis-calls-for-policies-for-greater-resilience\"><span style=\"font-weight: 400\">between $37 billion and $79 billion this year alone<\/span><\/a><span style=\"font-weight: 400\">; put in context, that latter projection is up to four times <\/span><a href=\"https:\/\/gh.bmj.com\/content\/4\/1\/e001159\"><span style=\"font-weight: 400\">the amount spent on HIV\/AIDs in sub-Saharan Africa in 2015<\/span><\/a><span style=\"font-weight: 400\">. <\/span><\/p>\n<p><span style=\"font-weight: 400\">This projected economic toll, in part, results from the swift and aggressive containment interventions many African countries have had to take in the midst of even single digit cases. In developed economies, the greater availability of ICU beds buffers against the need to introduce lockdowns at such a stage. <\/span><a href=\"https:\/\/www.tepunahamatatini.ac.nz\/2020\/04\/09\/a-stochastic-model-for-covid-19-spread-and-the-effects-of-alert-level-4-in-aotearoa-new-zealand\/\"><span style=\"font-weight: 400\">Consider New Zealand whose gradually escalating containment strategy<\/span><\/a><span style=\"font-weight: 400\"> has had some success. That country has <\/span><a href=\"https:\/\/www.rnz.co.nz\/news\/national\/412529\/153-intensive-care-beds-in-country-survey\"><span style=\"font-weight: 400\">about 560 beds for a population of four million<\/span><\/a><span style=\"font-weight: 400\">. Per the country\u2019s modeling, population wide containment to prevent the overload of its health system was not necessary until reported daily cases were in the low hundreds.<\/span><\/p>\n<p><span style=\"font-weight: 400\">The view of critical care as a deluxe aspect of health systems perhaps stems, in part, from <\/span><a href=\"https:\/\/www.atsjournals.org\/doi\/full\/10.1164\/rccm.200902-0201OC\"><span style=\"font-weight: 400\">observations in some developed countries that depict these wards<\/span><\/a><span style=\"font-weight: 400\"> as places where older patients with <\/span><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3568952\/\"><span style=\"font-weight: 400\">multiple comorbidities receive<\/span><\/a><span style=\"font-weight: 400\">\u00a0extremely expensive care in spite of poor prognoses. But the demographics of patients in sub-Saharan Africa\u2019s ICUs often differ significantly from this trend. <\/span><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3568952\/\"><span style=\"font-weight: 400\">An audit from Uganda<\/span><\/a><span style=\"font-weight: 400\">, for example, shows that patients in their ICU are often younger and without comorbidities. Moreover, some of the leading diagnoses requiring critical care, e.g. sepsis, and respiratory failure, <\/span><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/22937769\/\"><span style=\"font-weight: 400\">are of infectious etiology<\/span><\/a><span style=\"font-weight: 400\">. And yet mortality in this low income setting in sub-Saharan Africa was in excess of 40%. The resultant economic impact from lost QALYs and productivity of ICU patients in this cohort cannot be overstated. Robust critical care could help to mitigate this impact.<\/span><\/p>\n<p><span style=\"font-weight: 400\">A reverberating aphorism during these times is that covid-19 is the \u201cgreat equalizer\u201d\u2014one that has affected countries regardless of their wealth. It\u2019s true this pandemic has taught us that infectious diseases are not just threats unique to low and middle income countries. In that same vein, it ought to be the same equalizer that teaches us robust critical care should not be an aspect of care singularly reserved for industrialized nations. The projected loss of life and unprecedented economic losses that sub-Saharan Africa faces should spur immediate consideration for strengthening its critical care capacity from governments and donors alike.<\/span><\/p>\n<p><b><i>Edgar Asiimwe <\/i><\/b><i><span style=\"font-weight: 400\">is a senior medical student at Stanford University School of Medicine. He holds a MSc in global health from Duke University and a BSc in biology from La Roche College. He is an incoming intern in UCLA\u2019s internal medicine residency program and has a strong interest in global health and health system strengthening.<\/span><\/i><\/p>\n<p><b>Competing interests:<\/b><span style=\"font-weight: 400\"> None declared.\u00a0<\/span><\/p>\n<p><b><i>Saraswati Kache<\/i><\/b><i><span style=\"font-weight: 400\"> is a clinical professor in the Division of Critical Care, Department of Pediatrics at Stanford University Lucile Packard Children\u2019s Hospital. She has a strong interest in critical care in developing countries and is a member of Stanford University\u2019s Center for Global Health and Innovation.<\/span><\/i><\/p>\n<p><b>Competing interests:<\/b><span style=\"font-weight: 400\"> None declared. <\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>The ICU capacity that is critical to managing covid-19 complications is severely limited in much of the region, warn Edgar Asiimwe and Saraswati Kache [&#8230;]<\/p>\n<p><a class=\"btn btn-secondary understrap-read-more-link\" href=\"https:\/\/blogs.bmj.com\/bmj\/2020\/04\/23\/covid-19-and-sub-saharan-africas-critical-care-infrastructure\/\">More&#8230;<\/a><\/p>\n","protected":false},"author":1,"featured_media":47276,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[223],"tags":[],"class_list":["post-47274","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-guest-bloggers"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.4 - 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