{"id":46552,"date":"2020-01-31T18:27:57","date_gmt":"2020-01-31T17:27:57","guid":{"rendered":"https:\/\/blogs.bmj.com\/bmj\/?p=46552"},"modified":"2020-02-07T17:46:26","modified_gmt":"2020-02-07T16:46:26","slug":"jeffrey-aronson-when-i-use-a-word-coronas","status":"publish","type":"post","link":"https:\/\/blogs.bmj.com\/bmj\/2020\/01\/31\/jeffrey-aronson-when-i-use-a-word-coronas\/","title":{"rendered":"Jeffrey Aronson: When I Use a Word . . . Coronas"},"content":{"rendered":"<p><span style=\"font-weight: 400\">The <\/span><span style=\"font-weight: 400\">Coronaviruses were first identified by a group of virologists (J D Almeida, D M Berry, C H Cunningham, D Hamre, M S Hofstad, L Mallucci, K McIntosh, and D A J Tyrrell) who in <a href=\"https:\/\/doi.org\/10.1038\/220650b0\" target=\"_blank\" rel=\"noopener noreferrer\">1968<\/a> relayed their findings to the journal <em>Nature<\/em>, which published a brief annotation (Figure 1). As the journal reported, \u201cthese viruses are members of a previously unrecognized group which [the virologists] suggest should be called the coronaviruses, to recall the characteristic appearance by which these viruses are identified in the electron microscope.\u201d\u00a0<\/span>They had compared the \u201ccharacteristic \u2018fringe\u2019 of projections\u201d on the outside of the virus with the solar corona (not, as some have suggested, the points on a crown). Figure 2 illustrates this.<br \/>\n<img loading=\"lazy\" decoding=\"async\" class=\"alignleft wp-image-46589\" src=\"https:\/\/blogs.bmj.com\/bmj\/files\/2020\/01\/259.-Coronaviruses-1.png\" alt=\"\" width=\"697\" height=\"524\" \/><\/p>\n<p>&nbsp;<\/p>\n<figure id=\"attachment_46556\" aria-describedby=\"caption-attachment-46556\" style=\"width: 642px\" class=\"wp-caption aligncenter\"><a href=\"https:\/\/blogs.bmj.com\/bmj\/files\/2020\/01\/Fig2-1.png\"><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-46556 size-full\" src=\"https:\/\/blogs.bmj.com\/bmj\/files\/2020\/01\/Fig2-1.png\" alt=\"\" width=\"642\" height=\"342\" srcset=\"https:\/\/blogs.bmj.com\/bmj\/files\/2020\/01\/Fig2-1.png 642w, https:\/\/blogs.bmj.com\/bmj\/files\/2020\/01\/Fig2-1-300x160.png 300w, https:\/\/blogs.bmj.com\/bmj\/files\/2020\/01\/Fig2-1-640x341.png 640w\" sizes=\"auto, (max-width: 642px) 100vw, 642px\" \/><\/a><figcaption id=\"caption-attachment-46556\" class=\"wp-caption-text\"><em><strong>Figure 2:<\/strong> Left; the virions of the coronaviruses, right; the corona of the sun seen during an eclipse. <\/em><\/figcaption><\/figure>\n<p>&nbsp;<\/p>\n<p>As I have previously <a href=\"https:\/\/blogs.bmj.com\/bmj\/2018\/08\/17\/jeffrey-aronson-when-i-use-a-word-corticosteroids\/\" target=\"_blank\" rel=\"noopener noreferrer\">discussed<\/a>, the IndoEuropean root [S]KER is actually two separate roots with different meanings, giving rise to many unrelated words. For example, \u201cscherzo\u201d comes from the root [S]KER, to leap. On the other hand, \u201ccorona\u201d comes from a different root altogether, [S]KER, to turn or bend. It is the second of these with which I am concerned here.<\/p>\n<p>Some derivatives come via Old English: ring comes from hring, ridge from hrycg, a spine, and shrink from scrincan, to wither or shrivel up.<\/p>\n<p>Ruck is metathetically from the Old Norse hrukka, a crease or fold, and rucksack from the Old High German, hrukki, the back.<\/p>\n<p>Similarly, the Frankish word hrunkjan, to wrinkle gives the Old French word fronce, a pleat, from which we get flounce. Other Old French words renc and reng, meaning a line or row, give us ranch, rank, rink, and range, with derivatives such as arrange, derange, enrange, and outrange.<\/p>\n<p>In Latin curvus, bent or curved, gives us curb, curvature, curve, and curvet; crinis, hair, gives crinoline; crista, a tuft or crest, gives crest, crista, and cristate; and crispus (metathesized from cripsus), curly, gives crepe, crisp, and crispate. A rare ornithological word, crissum, the anal region of a bird under the tail, the vent-feathers or lower tail-coverts, comes from a curious Latin word, crisare, describing female hip wiggling during copulation. The <em>Oxford English Dictionary<\/em> coyly defined \u201ccrisare\u201d in the fascicle Consignificant\u2013Crouching, first published in May 1893, as \u201cclunem movere\u201d, to move the haunches, a description that is unchanged today.<\/p>\n<p>Kurtosis, a characteristic that defines the shape of a frequency distribution, comes from the Greek word \u03ba\u03c5\u03c1\u03c4\u03cc\u03c2, bulging or convex. Reduplication of KER to KIKRO gives cerclage, circa, circadian, circinate, circle, circum-, circus, cirque, cricoid, search, and recherch\u00e9, all via Latin, but eventually from the Greek \u03ba\u03af\u03c1\u03ba\u03bf\u03c2, a ring. Homer\u2019s metathetic form \u03ba\u03c1\u03af\u03ba\u03bf\u03c2 gives us the cricoid cartilage.<\/p>\n<p>From the Greek \u03ba\u03bf\u03c1\u1f7d\u03bd\u03b7, a crow or some seabird, comes the carrion crow, Corvus corone, with its curved beak, and from \u03ba\u03bf\u03c1\u1f7d\u03bd\u1f77\u03c2, curved, comes the Latin corona, a crown, chaplet or wreath, fillet or circlet of gold or other material. This gives us English loan words for certain foreign currencies: koruna from the Czech Republic, krona from Sweden and Iceland, and krone from Denmark and Norway. The Old English coin a crown, worth five old shillings (25 pence), has the same origin, as does the headgear.<\/p>\n<p>Latin corona also gives us corona, which has acquired many different meanings in different areas (Table 1).<br \/>\nIn addition to all these standard meanings, sybarites will recognize the word as the trade-name that the Havana firm of Manuel Lopez and Company chose for their cigars, first marketed in 1877, characterized by having long tapering bodies and blunt ends. It is also the name of a brand of beer.<\/p>\n<p>After the initial description of coronaviruses in 1968 there was a slow increase in the numbers of publications dealing with them, followed by two peaks, after two epidemics: the severe acute respiratory syndrome (SARS) coronavirus <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/30844511\" target=\"_blank\" rel=\"noopener noreferrer\">epidemic<\/a> in 2003-4 and an <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/23963154\" target=\"_blank\" rel=\"noopener noreferrer\">epidemic<\/a> of porcine epidemic diarrhoea in North America in 2013 (Figure 3). Identification of the first cases of Middle East respiratory syndrome (MERS or camel flu) in Saudi Arabia in 2012, and then elsewhere, also caused by a coronavirus, may also have contributed. I expect to see another peak following the current epidemic.<\/p>\n<figure id=\"attachment_46557\" aria-describedby=\"caption-attachment-46557\" style=\"width: 554px\" class=\"wp-caption aligncenter\"><a href=\"https:\/\/blogs.bmj.com\/bmj\/files\/2020\/01\/Fig3.png\"><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-46557 size-full\" src=\"https:\/\/blogs.bmj.com\/bmj\/files\/2020\/01\/Fig3.png\" alt=\"\" width=\"554\" height=\"380\" srcset=\"https:\/\/blogs.bmj.com\/bmj\/files\/2020\/01\/Fig3.png 554w, https:\/\/blogs.bmj.com\/bmj\/files\/2020\/01\/Fig3-300x206.png 300w\" sizes=\"auto, (max-width: 554px) 100vw, 554px\" \/><\/a><figcaption id=\"caption-attachment-46557\" class=\"wp-caption-text\"><em><strong>Figure 3:<\/strong> Numbers of publications with &#8220;coranaviruses&#8221; as text words or in titles (source PubMed)<\/em><\/figcaption><\/figure>\n<p>&nbsp;<\/p>\n<p style=\"text-align: center\"><strong>Table 1:<\/strong>\u00a0Different meanings of \u201ccorona\u201d and some derivatives<\/p>\n<p><a href=\"https:\/\/blogs.bmj.com\/bmj\/files\/2020\/01\/jeff_table_1.png\"><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-46561 size-full\" src=\"https:\/\/blogs.bmj.com\/bmj\/files\/2020\/01\/jeff_table_1.png\" alt=\"\" width=\"618\" height=\"1124\" srcset=\"https:\/\/blogs.bmj.com\/bmj\/files\/2020\/01\/jeff_table_1.png 618w, https:\/\/blogs.bmj.com\/bmj\/files\/2020\/01\/jeff_table_1-165x300.png 165w, https:\/\/blogs.bmj.com\/bmj\/files\/2020\/01\/jeff_table_1-563x1024.png 563w\" sizes=\"auto, (max-width: 618px) 100vw, 618px\" \/><\/a><\/p>\n<table style=\"height: 258px\" width=\"782\">\n<tbody>\n<tr style=\"border: 1px solid black\">\n<td style=\"border: 1px solid black;text-align: left\">\n<p style=\"text-align: center\"><b>This week&#8217;s interesting integer: 259<\/b><\/p>\n<p>&nbsp;<\/p>\n<ul>\n<li>259 is 1111 in base 6; in other words, it equals 6<sup>3<\/sup> + 6<sup>2<\/sup> + 6<sup>1<\/sup> + 6<sup>0<\/sup><\/li>\n<\/ul>\n<ul>\n<li>259 is a semiprime, i.e. the product of two primes, 7 \u00d7 37. It is also a Sophie Germain semiprime, any semiprime number p for which 2p + 1 (in this case 519 = 3 \u00d7 173) is also semiprime. Primes and semiprimes of this type are named after the French mathematician Sophie Germain (1776\u20131831). Sophie Germain primes have applications in public key cryptography and primality testing.<\/li>\n<\/ul>\n<p>&nbsp;<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>&nbsp;<\/p>\n<p style=\"text-align: left\"><span style=\"font-weight: 400\"><em><strong>Jeffrey Aronson<\/strong>\u00a0is a clinical pharmacologist, working in the Centre for Evidence Based Medicine in Oxford&#8217;s Nuffield Department of Primary Care Health Sciences. He is also president emeritus of the British Pharmacological Society.<\/em><\/span><\/p>\n<p><strong>Competing interests:<\/strong> None declared.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>The Coronaviruses were first identified by a group of virologists (J D Almeida, D M Berry, C H Cunningham, D Hamre, M S Hofstad, L Mallucci, K McIntosh, and D [&#8230;]<\/p>\n<p><a class=\"btn btn-secondary understrap-read-more-link\" href=\"https:\/\/blogs.bmj.com\/bmj\/2020\/01\/31\/jeffrey-aronson-when-i-use-a-word-coronas\/\">More&#8230;<\/a><\/p>\n","protected":false},"author":1,"featured_media":38359,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[5762],"tags":[],"class_list":["post-46552","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-jeff-aronsons-words"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.4 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Jeffrey Aronson: When I Use a Word . . . 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