{"id":42964,"date":"2018-09-06T15:53:44","date_gmt":"2018-09-06T14:53:44","guid":{"rendered":"https:\/\/blogs.bmj.com\/bmj\/?p=42964"},"modified":"2018-09-17T11:53:37","modified_gmt":"2018-09-17T10:53:37","slug":"lucy-selman-reducing-preventable-stillbirth-rates-in-the-uk","status":"publish","type":"post","link":"https:\/\/blogs.bmj.com\/bmj\/2018\/09\/06\/lucy-selman-reducing-preventable-stillbirth-rates-in-the-uk\/","title":{"rendered":"Lucy Selman: Reducing preventable stillbirth rates in the UK"},"content":{"rendered":"<p class=\"standfirst\">More must be done\u2014Nine babies every day is just too many<\/p>\n<p><!--more--><br \/>\n<span style=\"font-weight: 400\"><a href=\"https:\/\/blogs.bmj.com\/bmj\/files\/2018\/09\/lucy_selman.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"alignleft size-full wp-image-42965\" src=\"https:\/\/blogs.bmj.com\/bmj\/files\/2018\/09\/lucy_selman.jpg\" alt=\"\" width=\"160\" height=\"160\" srcset=\"https:\/\/blogs.bmj.com\/bmj\/files\/2018\/09\/lucy_selman.jpg 160w, https:\/\/blogs.bmj.com\/bmj\/files\/2018\/09\/lucy_selman-150x150.jpg 150w\" sizes=\"auto, (max-width: 160px) 100vw, 160px\" \/><\/a>The low, featureless hum as the midwife moved the Doppler foetal monitor across my belly is a sound I wouldn\u2019t wish on anyone. Heavy with meaning, it hung in the room, dragging my husband and me into an unimagined future. Our daughter, Ada, had died. The next morning I would be induced, and at 13:52 I\u2019d give birth to her. <\/span><\/p>\n<p><span style=\"font-weight: 400\">Three months later, we met our consultant to discuss Ada\u2019s post-mortem and the results of the myriad blood tests and swabs taken from me before and after she died. My waters had broken at 26 weeks, 4 days. She died six days later. The cause of death was pneumonitis, and there were signs of bacterial infection in the placenta. Ada\u2019s skin showed traces of streptococcus (though not <\/span><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/29117322\"><span style=\"font-weight: 400\">group B<\/span><\/a><span style=\"font-weight: 400\">, which is a major cause of stillbirth). It was not certain whether Ada\u2019s infection occurred before or after the foetal membranes ruptured, but infection markers in my blood were elevated when I arrived at the hospital with my waters broken, and the consultant\u2019s best guess was that a sub-clinical infection caused the membranes to rupture. Two months earlier I had had an asymptomatic urinary tract infection and been given antibiotics. A couple of weeks later I felt mild UTI symptoms, but a dipstick test was negative. I had no other obvious symptoms\u2014no cough, cold, flu or nausea. <\/span><\/p>\n<p><span style=\"font-weight: 400\">In the UK, <\/span><a href=\"https:\/\/www.tommys.org\/our-organisation\/charity-research\/pregnancy-statistics\/stillbirth\"><span style=\"font-weight: 400\">1 in every 225 births is a stillbirth<\/span><\/a><span style=\"font-weight: 400\">\u2014a baby born dead after 24 completed weeks of pregnancy. That\u2019s around 3,400 babies dying every year, or 9 every day, on average. 23 high-income countries have lower <\/span><a href=\"https:\/\/www.thelancet.com\/journals\/lancet\/article\/PIIS0140-6736(15)01020-X\/fulltext?code=lancet-site\"><span style=\"font-weight: 400\">stillbirth rates<\/span><\/a><span style=\"font-weight: 400\"> than the UK. In high-income countries, substandard care contributes to 20\u201330% of all stillbirths. The charities <\/span><a href=\"https:\/\/www.sands.org.uk\/\"><span style=\"font-weight: 400\">SANDS<\/span><\/a><span style=\"font-weight: 400\"> and <\/span><a href=\"https:\/\/www.tommys.org\/\"><span style=\"font-weight: 400\">Tommy\u2019s<\/span><\/a><span style=\"font-weight: 400\"> work to improve these figures, and the experiences of bereaved parents. But clinical action, government investment and further research is needed. Here are six ways we can reduce stillbirths in the UK.<\/span><\/p>\n<ul>\n<li><b>Identify and treat urinary tract infections. <span style=\"font-weight: 400\">UTIs, including asymptomatic bacteriuria, are common, affecting <\/span><a href=\"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/full\/10.1576\/toag.10.3.156.27418\"><span style=\"font-weight: 400\">8% of pregnant women<\/span><\/a><span style=\"font-weight: 400\">, and have <\/span><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/12113866\"><span style=\"font-weight: 400\">known risks<\/span><\/a><span style=\"font-weight: 400\">. Screening in early pregnancy via the gold standard of cultured urine tests is routine, enabling prescription of antibiotics when indicated. But <\/span><a href=\"https:\/\/cks.nice.org.uk\/urinary-tract-infection-lower-women#!scenario:3\"><span style=\"font-weight: 400\">follow-up<\/span><\/a><span style=\"font-weight: 400\"> is required: a urine culture should also be performed seven days after completion of antibiotic treatment as a test of cure. In cases in which a pregnant woman presents with UTI symptoms, or has had a previous infection during the pregnancy, dipstick (reagent strip) tests <\/span><a href=\"https:\/\/cks.nice.org.uk\/urinary-tract-infection-lower-women#!scenario:4\"><span style=\"font-weight: 400\">should not be relied upon<\/span><\/a><span style=\"font-weight: 400\"> due to their <\/span><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/19155905\"><span style=\"font-weight: 400\">insufficient sensitivity<\/span><\/a><span style=\"font-weight: 400\">. An <\/span><a href=\"http:\/\/www.sign.ac.uk\/assets\/sign88_algorithm_pregnant_women.pdf\"><span style=\"font-weight: 400\">algorithm<\/span><\/a><span style=\"font-weight: 400\"> and a <\/span><a href=\"http:\/\/www.sign.ac.uk\/sign-88-management-of-suspected-bacterial-urinary-tract-infection-in-adults.html\"><span style=\"font-weight: 400\">phone app<\/span><\/a><span style=\"font-weight: 400\"> summarising the management of suspected lower UTIs in pregnant women are available through the Scottish Intercollegiate Guidelines Network.<\/span><\/b><\/li>\n<\/ul>\n<ul>\n<li><b>Raise awareness among expectant mothers. <span style=\"font-weight: 400\">It is vital to talk about warning signs and symptoms, and the steps women can take to reduce their risk of stillbirth. Most stillbirths are outside a woman\u2019s control, but there are <\/span><a href=\"https:\/\/www.nhs.uk\/conditions\/stillbirth\/prevention\/\"><span style=\"font-weight: 400\">actions women can take<\/span><\/a><span style=\"font-weight: 400\"> to reduce their risk. For example, <\/span><a href=\"https:\/\/www.tommys.org\/pregnancy\/baby-moving-less\/reporting-reduced-fetal-movements\"><span style=\"font-weight: 400\">reporting reduced foetal movement<\/span><\/a><span style=\"font-weight: 400\"> after 24 weeks, and <\/span><a href=\"https:\/\/www.tommys.org\/pregnancy-information\/sleep-side-pregnancy-campaign\"><span style=\"font-weight: 400\">sleeping on your side<\/span><\/a><span style=\"font-weight: 400\"> after 28 weeks. <\/span><\/b><\/li>\n<\/ul>\n<ul>\n<li><strong>Monitor stillbirth rates<\/strong>. <span style=\"font-weight: 400\">The UK conducts <\/span><a href=\"https:\/\/www.hqip.org.uk\/resource\/mbrrace-uk-perinatal-mortality-surveillance-report-2018\/#.W1hMnPZFx1s\"><span style=\"font-weight: 400\">national audits on perinatal mortality<\/span><span style=\"font-weight: 400\">. <\/span><\/a><span style=\"font-weight: 400\">While these show that over the past 4 years the rate has started to decrease, there was no improvement from 2015 to 2016, and substandard antepartum and intrapartum care is too often present when a stillbirth occurs. For example, improvements in care which may have made a difference to the outcome have been identified in 60-80% of babies who die at term, either shortly before or during birth. In England, the <\/span><a href=\"https:\/\/www.england.nhs.uk\/mat-transformation\/saving-babies\/\"><span style=\"font-weight: 400\">Saving Babies\u2019 Lives Stillbirth Care Bundle<\/span><\/a><span style=\"font-weight: 400\"> was launched in 2016 as a response to audit findings. This is a step in the right direction, though its effectiveness is not yet known. <\/span><\/li>\n<\/ul>\n<ul>\n<li><strong>Investigate stillbirths<\/strong>.<span style=\"font-weight: 400\"> All stillbirths deserve high-quality investigation. In three-quarters of cases, detailed evaluation enables identification of probable or possible causes of death, compared with only about half when medical records alone are investigated. Bereaved parents should have access to a post-mortem and placental histopathology, and the opportunity to discuss the death with their consultant in a timely, compassionate manner. The quality of local reviews is <\/span><a href=\"https:\/\/www.rcog.org.uk\/eachbabycounts\"><span style=\"font-weight: 400\">variable<\/span><\/a><span style=\"font-weight: 400\"> and many would benefit from improvement. The national <\/span><a href=\"https:\/\/www.npeu.ox.ac.uk\/pmrt\"><span style=\"font-weight: 400\">Perinatal Mortality Review Tool<\/span><\/a><span style=\"font-weight: 400\"> (PMRT) launched this year aims to support high-quality, multidisciplinary local review of the care provided at all stages of the maternity and neonatal pathway. Again, its effectiveness and acceptability to parents is not yet known. <\/span><\/li>\n<\/ul>\n<ul>\n<li><strong>Conduct research<\/strong>.<span style=\"font-weight: 400\"> About <\/span><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/22166605\"><span style=\"font-weight: 400\">half<\/span><\/a><span style=\"font-weight: 400\"> of all stillbirths are linked to complications with the placenta, and key research focuses on <\/span><a href=\"https:\/\/www.tommys.org\/our-organisation\/our-research\/research-stillbirth\"><span style=\"font-weight: 400\">understanding placental pathways to stillbirth<\/span><\/a><span style=\"font-weight: 400\">. Ascending bacterial infection prior to membrane rupture is the most important <\/span><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3893929\/\"><span style=\"font-weight: 400\">infectious cause<\/span><\/a><span style=\"font-weight: 400\"> of stillbirths\u2014and the most probable cause of Ada\u2019s death. Developing a better understanding of this complication and how to reduce its occurrence is vital. Other important areas for research have been identified by the <\/span><a href=\"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/full\/10.1002\/uog.15738\"><span style=\"font-weight: 400\">Stillbirth Priority Setting Partnership<\/span><\/a><span style=\"font-weight: 400\">.<\/span><\/li>\n<\/ul>\n<ul>\n<li><strong>Address stigma and fatalism<\/strong>. <span style=\"font-weight: 400\">In high-income countries, <\/span><a href=\"https:\/\/www.thelancet.com\/journals\/lancet\/article\/PIIS0140-6736(15)01020-X\/fulltext?code=lancet-site\"><span style=\"font-weight: 400\">about half<\/span><\/a><span style=\"font-weight: 400\"> of parents who have suffered a stillbirth feel they should not talk about their stillborn baby because it makes others feel uncomfortable, and two-thirds of parents feel that the people around them believe most stillbirths are unavoidable. My personal interest in information about cause of death was interpreted by some people as a desire for control over a sad but inevitable situation, rather than a normal reaction to my child\u2019s death. Social perceptions and actions that dismiss the importance of a stillborn child or parental grief, or support the idea that a child was never \u201csupposed\u201d to live, not only harm bereaved parents, but also <\/span><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/21496915?dopt=Abstract\"><span style=\"font-weight: 400\">undermine efforts to reduce stillbirth rates<\/span><\/a><span style=\"font-weight: 400\">.<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400\">Not all stillbirths are preventable, and we don\u2019t know with certainty that Ada\u2019s was. What is certain is that more must be done in the UK to reduce stillbirths\u2014and the family devastation they bring\u2014by ensuring excellence in the care of women during pregnancy and labour. Nine babies every day is just too many.<\/span><\/p>\n<p><em><span style=\"font-weight: 400\"><strong>Lucy Selman<\/strong> is a senior research fellow in Population Health Sciences, Bristol Medical School, University of Bristol.<\/span><\/em><\/p>\n<p><em><span style=\"font-weight: 400\"><strong>Conflicting interests<\/strong>: None declared.<\/span><\/em><\/p>\n<p><span style=\"font-weight: 400\">Twitter: <a href=\"https:\/\/twitter.com\/lucy_selman?lang=en-gb\">@Lucy_Selman<\/a><\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>More must be done\u2014Nine babies every day is just too many [&#8230;]<\/p>\n<p><a class=\"btn btn-secondary understrap-read-more-link\" href=\"https:\/\/blogs.bmj.com\/bmj\/2018\/09\/06\/lucy-selman-reducing-preventable-stillbirth-rates-in-the-uk\/\">More&#8230;<\/a><\/p>\n","protected":false},"author":1,"featured_media":41788,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[236],"tags":[],"class_list":["post-42964","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-nhs"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.4 - 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