{"id":40707,"date":"2017-11-24T17:40:54","date_gmt":"2017-11-24T16:40:54","guid":{"rendered":"https:\/\/blogs.bmj.com\/bmj\/?p=40707"},"modified":"2017-12-01T12:38:21","modified_gmt":"2017-12-01T11:38:21","slug":"jeffrey-aronson-when-i-use-a-word-intro-and-outro-exnovation-and-outroduction","status":"publish","type":"post","link":"https:\/\/blogs.bmj.com\/bmj\/2017\/11\/24\/jeffrey-aronson-when-i-use-a-word-intro-and-outro-exnovation-and-outroduction\/","title":{"rendered":"Jeffrey Aronson: When I use a word . . . Intro and outro: exnovation and outroduction"},"content":{"rendered":"<p><a href=\"https:\/\/blogs.bmj.com\/bmj\/files\/2014\/12\/jeffrey_aronson.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"alignleft wp-image-32935\" src=\"https:\/\/blogs.bmj.com\/bmj\/files\/2014\/12\/jeffrey_aronson-223x300.jpg\" alt=\"jeffrey_aronson\" width=\"112\" height=\"151\" srcset=\"https:\/\/blogs.bmj.com\/bmj\/files\/2014\/12\/jeffrey_aronson-223x300.jpg 223w, https:\/\/blogs.bmj.com\/bmj\/files\/2014\/12\/jeffrey_aronson.jpg 446w\" sizes=\"auto, (max-width: 112px) 100vw, 112px\" \/><\/a><a href=\"https:\/\/blogs.bmj.com\/bmj\/2017\/11\/17\/jeffrey-aronson-when-i-use-a-word-intro-and-outro-de-adoption\">Last week<\/a> I discussed the use of the word \u201cde-adoption\u201d in the title of a paper recently published in <em>The BMJ<\/em>: \u201cDe-adoption and exnovation in the use of carotid revascularisation\u201d. I analysed \u201cde-adoption\u201d and suggested that \u201cdisinvestment\u201d was a preferable term\u2014well established, more commonly used, and more relevant. Here I analyse the neologism \u201cexnovation\u201d.<\/p>\n<p>Searching PubMed, Embase, Medline, and PsycINFO for \u201cexnovation\u201d as a textword I found only five examples, three of them in the past\u00a0two years. The <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/22040949\">earliest<\/a> dated from 2011. However, there are earlier instances in the US business literature. In 1981 it was <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/10253688\">defined<\/a> as \u201cthe process whereby an organization decides to divest itself of an innovation that it had previously adopted\u201d. More concisely, on the front cover of a 2015 issue of <i>Business &amp; Economy<\/i>, \u201cIndia\u2019s most influential business &amp; economy magazine\u201d, \u201cexnovation\u201d was defined as \u201creverse innovation\u201d.<\/p>\n<p>The phoneme ex-, which we use as a prefix, was both a word and a prefix in Greek (\u1f10\u03be) and Latin (ex). In both languages it meant out of, and in both it had alternative forms, in Greek \u1f10\u03ba and in Latin \u0113. Two forms were needed, for the sake of euphonious pronunciation. In Greek \u1f10\u03be occurred only before vowels, as in \u1f10\u03be\u03b1\u03bd\u03b8\u03b7\u03bc\u03b1, an efflorescence or eruption, \u1f10\u03be\u03b5\u03bd\u03c4\u03b5\u03c1\u03af\u03b6\u03b5\u03b9\u03bd, to disembowel, and \u1f10\u03be\u03cc\u03d5\u03b8\u03b1\u03bb\u03bc\u03bf\u03c2, having prominent eyes, giving us exanthem, exenterate, and exophthalmos. Before consonants \u1f10\u03be was replaced by \u1f10\u03ba, which became ec- in Latin and English, giving derivatives such as ecbolic (\u1f10\u03ba\u03b2\u03bf\u03bb\u03ae, expulsion), ecchymosis (\u1f10\u03ba\u03c7\u03c5\u03bc\u1f77\u03b6\u03c9, to extract juice from), and Ecstasy (\u1f14\u03ba\u03c3\u03c4\u03b1\u03c3\u03b9\u03c2, outward movement).<\/p>\n<p>In classical Latin the prefix ex- was used before all vowels and some consonants (<i>c<\/i>, <i>h<\/i>, <i>p<\/i>, <i>q<\/i>, and <i>t<\/i>); before <i>f<\/i> it became ef- and before other consonants it became \u0113. All these various forms are represented in many English derivatives; for example, examination, excoriation, exhalation, expectorant, exquisite, extensor, effervescent, eburnation, and eventration. When an <i>s<\/i> followed the prefix, it was commonly omitted in mediaeval Latin, and therefore also in some English derivatives, such as exudate (from sudor, sweat) and extinct (from stinguere, to quench), but retained in others, such as exsanguinate and exsciccate.<\/p>\n<p>I and my colleagues have <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/22460109\">defined<\/a> a rewardable medicinal innovation as \u201ca product that provides, through a step change, something novel, with the potential or proven ability to yield, for individuals and\/or their society, a treatment not previously available or a clinically significant improvement in treatment, with large health gains and a favourable benefit to harm balance, at an acceptable cost.\u201d This implies that an intervention, apparently innovative, should not be generally adopted if it has not been properly tested or if it is not cost effective, even if it appears to be beneficial. If it is inappropriately adopted, the decision may need to be reversed at a later stage; hence the ideas of de-adoption and exnovation.<\/p>\n<p>The in- in <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/22690008\">innovation<\/a> is a Latin prefix meaning into, in, or within, on or upon, towards or against; the opposite is ex or \u0113. If one wanted to form a word meaning the opposite of innovation, one would use \u0113, as in enervation and enucleation, rather than ex. In other words, the word would be \u201cenovation\u201d rather than \u201cexnovation\u201d. However, I have a different suggestion.<\/p>\n<p>In 1967 a group called <a href=\"http:\/\/www.iankitching.me.uk\/music\/bonzos\/history.html\">Bonzo Dog Doo-Dah Band<\/a> recorded an album called <i>Gorilla<\/i> (\u201cdedicated to Kong who must have been a great guy\u201d), including a track called \u201c<a href=\"https:\/\/www.youtube.com\/watch?v=hcrUuCDFLOQ&amp;list=RDhcrUuCDFLOQ\">The Intro and the Outro<\/a>\u201d. The narrator Vivian Stanshall starts by introducing the band: \u201cLike to introduce Legs Larry Smith drums and Sam Spoons rhythm pole and Vernon Dudley Bohey Nowell base guitar and Neil Innes piano; come in Rodney Slater on the saxophone with Roger Ruskin Speare on tenor sax; hi Vivian Stanshall trumpet\u201d, and continues by naming others, who ostensibly join in: \u201cbig hello to Big John Wayne xylophone and Robert Morley guitar, Billy Butlin spoons; \u2026 Princess Anne on sousaphone; \u2026over there Eric Clapton ukulele (hi Eric); \u2026 a sessions gorilla on vox humana; \u2026 digging General de Gaulle on accordion (really wild General), \u2026 Roy Rogers on Trigger; \u2026Count Basie Orchestra on triangle; \u2026 Quasimodo on bells; \u2026 J Arthur Rank on gong\u201d. The title of the piece contained the first instance of the word \u201coutro\u201d, which is now defined in the <i>OED<\/i> as \u201ca concluding section, esp. of a piece of music or a broadcast programme\u201d.<\/p>\n<p>So, since \u201cintro\u201d is a contraction of \u201cintroduction\u201d, literally \u201cleading inwards\u201d, I suggest instead of \u201cexnovation\u201d another, possibly more attractive, neologism\u2014outroduction.<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-40713 aligncenter\" src=\"https:\/\/blogs.bmj.com\/bmj\/files\/2017\/11\/intro_outro.png\" alt=\"\" width=\"824\" height=\"372\" \/><\/p>\n<p>&nbsp;<\/p>\n<p><i>Gorilla<\/i>, the Bonzo Dog Doo-Dah Band\u2019s 1967 album (remastered with bonus tracks in this CD version on EMI\u2019s Liberty label in 2007), featuring \u201cThe Intro and the Outro\u201d (track 9)<\/p>\n<p><em><strong>Jeffrey Aronson<\/strong>\u00a0is a clinical pharmacologist, working in the Centre for Evidence Based Medicine in Oxford&#8217;s Nuffield Department of Primary Care Health Sciences. He is also president emeritus of the British Pharmacological Society.<\/em><\/p>\n<p><strong>Competing interests:<\/strong>\u00a0None declared.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Last week I discussed the use of the word \u201cde-adoption\u201d in the title of a paper recently published in The BMJ: \u201cDe-adoption and exnovation in the use of carotid revascularisation\u201d. 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