{"id":38162,"date":"2017-01-13T16:45:28","date_gmt":"2017-01-13T15:45:28","guid":{"rendered":"https:\/\/blogs.bmj.com\/bmj\/?p=38162"},"modified":"2017-01-16T14:56:47","modified_gmt":"2017-01-16T13:56:47","slug":"jeffrey-aronson-when-i-use-a-word-apoptosis","status":"publish","type":"post","link":"https:\/\/blogs.bmj.com\/bmj\/2017\/01\/13\/jeffrey-aronson-when-i-use-a-word-apoptosis\/","title":{"rendered":"Jeffrey Aronson: When I use a word . . . Apoptosis"},"content":{"rendered":"

In their landmark paper<\/a> in the British Journal of Cancer<\/em> 45 years ago, Kerr, Wyllie, and Currie reported a phenomenon that they described as \u201ccontrolled cell deletion\u201d. They proposed calling it \u201capoptosis\u201d and explained the term in a footnote, as follows:<\/p>\n

The word \u201capoptosis\u201d (\u1f01\u03c0\u1f79\u03c0\u03c4\u03c9\u03c3\u03b9\u03c3) is used in Greek to describe the \u201cdropping off\u201d or \u201cfalling off\u201d of petals from flowers, or leaves from trees. To show the derivation clearly, we propose that the stress should be on the penultimate syllable, the second half of the word being pronounced like \u201cptosis\u201d (with the \u201cp\u201d silent), which comes from the same root \u201cto fall\u201d and is already used to describe drooping of the upper eyelid.<\/em><\/p>\n

This statement contains two spelling errors and an incorrect assumption. The first error is in the breathing over the alpha. All Greek words that begin with a vowel or the letter \u03c1 (rho) are marked with a diacritic called \u03c0\u03bd\u03b5\u1fe6\u03bc\u03b1, a breathing, to indicate the presence or absence of aspiration. For example, \u1f00\u03bc\u03ac\u03c1\u03b1\u03bd\u03c4\u03bf\u03c2, unfading, has a smooth breathing (like a comma) above the initial alpha, and is pronounced amarantos, whence \u201camaranth\u201d, a fabled never fading flower, an emblem of immortality. In contrast, \u1f01\u03bc\u03b1\u03c1\u03c4\u1f77\u03b1, a failure, has a rough breathing (like a reversed apostrophe) above the initial alpha, and is pronounced hamartia, whence \u201chamartoma\u201d. Kerr et al used a rough breathing instead of a smooth one. Secondly, a sigma at the end of a word was written with a symbol, \u03c2, distinct from the ordinary sigma, \u03c3; Kerr et al used the ordinary sigma in the final place. The Greek word is not \u1f01\u03c0\u1f79\u03c0\u03c4\u03c9\u03c3\u03b9\u03c3 but \u1f00\u03c0\u1f79\u03c0\u03c4\u03c9\u03c3\u03b9\u03c2.<\/p>\n

The incorrect assumption in the footnote is in proposing that the second p<\/em> in \u201capoptosis\u201d, should be silent. This is wrong for two reasons. Firstly, the Greeks pronounced the \u03c0 at the start of \u03c0\u03c4\u1ff6\u03c3\u03b9\u03c2. Secondly, although \u201cptosis\u201d is pronounced in English with the p<\/em> silent, the p<\/em> is sounded when ptosis is a suffix, as in blepharoptosis, metemptosis, nephroptosis, proctoptosis, proptosis, and visceroptosis. For \u201capoptosis\u201d the Oxford English Dictionary<\/em>, which uses the International Phonetic Alphabet, offers \/\u02ccap\u0252p\u02c8t\u0259\u028as\u1d7bs\/ as the pronunciation.<\/p>\n

The IndoEuropean root PET meant to rush (\u03c0\u03c1\u03bf\u03c0\u1f73\u03c4\u1ff6\u03c2, impetuously or petulantly) or to fly (like a pterodactyl or archaeopteryx). Competitors rush to win and impetigo rushes across the skin. In Greek \u03c0\u03bf\u03c4\u1fb0\u03bc\u1f79\u03c2 is a rushing river, in which we may see a hippopotamus, a river horse, although not in Mesopotamia, which lies between two rivers, the Tigris and Euphrates, and in Oxford<\/a> between the upper and lower levels of the River Cherwell.<\/p>\n

Since what goes up must come down, a Greek derivative of PET, the reduplicated \u03c0\u1f77\u03c0\u03c4\u03b5\u03b9\u03bd meant to fall precipitously, literally and metaphorically; \u03c0\u03c4\u1ff6\u03c3\u03b9\u03c2 was a fall or calamity or the arrangement of terms in a syllogism; \u03c0\u03c4\u03c9\u03bc\u03b9\u03c3\u03bc\u1f79\u03c2 was the falling sickness, epilepsy; and \u03c0\u03c4\u1ff6\u03bc\u03b1 was a fallen body, a corpse. Ptomaine<\/a>, any of a group of amines formed by putrefaction of animal tissues (e.g. cadaverine), could supposedly kill you by food poisoning.<\/p>\n

With p<\/em> changing to f<\/em>, as pater becomes father<\/a>, PET begat feather (Greek \u03c0\u03c4\u03b5\u03c1\u03cc\u03bd) <\/em>and fern (\u03c0\u03c4\u03b5\u03c1\u03af\u03c2)<\/em>. From Old Latin petna, came penna, a feather, giving pennon and pennant (swallow tailed flags) and pen, a writing implement made from a bird\u2019s feather. Pinna in Latin was not only a feather but also a fin or a flap, like the pinna of the ear.<\/p>\n

Since the apoptosis paper was published it has been cited over 16 000 times (Figure). The first comment, an editorial<\/a> in The Lancet<\/em>, appeared within three months. Its anonymous author thought that the phenomenon would \u201csurely stimulate ideas for new experimentation in areas such as ontogenesis, teratogenesis, carcinogenesis, and tumour regression\u201d, but the process, he thought, might not be controlled, and he criticised the invented term: \u201cIn most flowers the falling of the first petal is followed soon by the fall of the last, and for deciduous plants the falling of the first leaves signifies that massive autumnal necrosis will soon follow. The term is, therefore, not quite right etymologically.\u201d Be that as it may, \u201capoptosis\u201d has stuck.<\/p>\n

In classical Greek \u1f00\u03c0\u1f79\u03c0\u03c4\u03c9\u03c3\u03b9\u03c2 also meant a falling in a grammatical sense\u2014declension, a system of cases and case-endings. Several years ago the chairman of a visiting group of academics tasked with scrutinising our teaching skills loftily told us at the end of the day that we were free to go home, and since we were Oxford academics he presumed that we would spend our evening \u201cconjugating Latin nouns\u201d. Verbs are conjugated, nouns are declined. A colleague whispered to me that he thought he would rather go home and conjugate his wife.<\/p>\n

<\/p>\n

Upper panel: Numbers of citations of the 1972 paper by Kerr et al year by year (source Google Scholar); interest did not start to grow until about 1990, although the paper had by that time garnered nearly 400 citations, making it something of a citation classic before it really got going.<\/p>\n

Lower panel: Numbers of publications indexed under \u201capoptosis\u201d in PubMed; the numbers of publications have far outstripped the numbers of citations, especially since 2000, when citations have started to fall, like falling leaves, as the concept has become taken for granted.<\/p>\n

\"jeffrey_aronson\"<\/a><\/p>\n

 <\/p>\n

Jeffrey Aronson<\/strong> is a clinical pharmacologist, working in the Centre for Evidence Based Medicine in Oxford’s Nuffield Department of Primary Care Health Sciences. He is also president emeritus of the British Pharmacological Society.<\/em><\/p>\n

Competing interests:<\/strong>\u00a0None declared.<\/p>\n

 <\/p>\n","protected":false},"excerpt":{"rendered":"

In their landmark paper in the British Journal of Cancer 45 years ago, Kerr, Wyllie, and Currie reported a phenomenon that they described as \u201ccontrolled cell deletion\u201d. They proposed calling […]<\/p>\n

More…<\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[5762],"tags":[],"class_list":["post-38162","post","type-post","status-publish","format-standard","hentry","category-jeff-aronsons-words"],"yoast_head":"\nJeffrey Aronson: When I use a word . . . Apoptosis - The BMJ<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/blogs.bmj.com\/bmj\/2017\/01\/13\/jeffrey-aronson-when-i-use-a-word-apoptosis\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Jeffrey Aronson: When I use a word . . . Apoptosis - The BMJ\" \/>\n<meta property=\"og:description\" content=\"In their landmark paper in the British Journal of Cancer 45 years ago, Kerr, Wyllie, and Currie reported a phenomenon that they described as \u201ccontrolled cell deletion\u201d. They proposed calling [...]More...\" \/>\n<meta property=\"og:url\" content=\"https:\/\/blogs.bmj.com\/bmj\/2017\/01\/13\/jeffrey-aronson-when-i-use-a-word-apoptosis\/\" \/>\n<meta property=\"og:site_name\" content=\"The BMJ\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/bmjdotcom\/\" \/>\n<meta property=\"article:published_time\" content=\"2017-01-13T15:45:28+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2017-01-16T13:56:47+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/blogs.bmj.com\/bmj\/files\/2017\/01\/aronson_apoptosis2.png\" \/>\n<meta name=\"author\" content=\"BMJ\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:creator\" content=\"@bmj_latest\" \/>\n<meta name=\"twitter:site\" content=\"@bmj_latest\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"BMJ\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"4 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/blogs.bmj.com\\\/bmj\\\/2017\\\/01\\\/13\\\/jeffrey-aronson-when-i-use-a-word-apoptosis\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/blogs.bmj.com\\\/bmj\\\/2017\\\/01\\\/13\\\/jeffrey-aronson-when-i-use-a-word-apoptosis\\\/\"},\"author\":{\"name\":\"BMJ\",\"@id\":\"https:\\\/\\\/blogs.bmj.com\\\/bmj\\\/#\\\/schema\\\/person\\\/ba3da426ed20e8f1d933ca367d8216fe\"},\"headline\":\"Jeffrey Aronson: When I use a word . . . Apoptosis\",\"datePublished\":\"2017-01-13T15:45:28+00:00\",\"dateModified\":\"2017-01-16T13:56:47+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/blogs.bmj.com\\\/bmj\\\/2017\\\/01\\\/13\\\/jeffrey-aronson-when-i-use-a-word-apoptosis\\\/\"},\"wordCount\":886,\"commentCount\":0,\"publisher\":{\"@id\":\"https:\\\/\\\/blogs.bmj.com\\\/bmj\\\/#organization\"},\"image\":{\"@id\":\"https:\\\/\\\/blogs.bmj.com\\\/bmj\\\/2017\\\/01\\\/13\\\/jeffrey-aronson-when-i-use-a-word-apoptosis\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/blogs.bmj.com\\\/bmj\\\/files\\\/2017\\\/01\\\/aronson_apoptosis2.png\",\"articleSection\":[\"Jeff Aronson's Words\"],\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"CommentAction\",\"name\":\"Comment\",\"target\":[\"https:\\\/\\\/blogs.bmj.com\\\/bmj\\\/2017\\\/01\\\/13\\\/jeffrey-aronson-when-i-use-a-word-apoptosis\\\/#respond\"]}]},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/blogs.bmj.com\\\/bmj\\\/2017\\\/01\\\/13\\\/jeffrey-aronson-when-i-use-a-word-apoptosis\\\/\",\"url\":\"https:\\\/\\\/blogs.bmj.com\\\/bmj\\\/2017\\\/01\\\/13\\\/jeffrey-aronson-when-i-use-a-word-apoptosis\\\/\",\"name\":\"Jeffrey Aronson: When I use a word . . . Apoptosis - The BMJ\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/blogs.bmj.com\\\/bmj\\\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\\\/\\\/blogs.bmj.com\\\/bmj\\\/2017\\\/01\\\/13\\\/jeffrey-aronson-when-i-use-a-word-apoptosis\\\/#primaryimage\"},\"image\":{\"@id\":\"https:\\\/\\\/blogs.bmj.com\\\/bmj\\\/2017\\\/01\\\/13\\\/jeffrey-aronson-when-i-use-a-word-apoptosis\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/blogs.bmj.com\\\/bmj\\\/files\\\/2017\\\/01\\\/aronson_apoptosis2.png\",\"datePublished\":\"2017-01-13T15:45:28+00:00\",\"dateModified\":\"2017-01-16T13:56:47+00:00\",\"breadcrumb\":{\"@id\":\"https:\\\/\\\/blogs.bmj.com\\\/bmj\\\/2017\\\/01\\\/13\\\/jeffrey-aronson-when-i-use-a-word-apoptosis\\\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\\\/\\\/blogs.bmj.com\\\/bmj\\\/2017\\\/01\\\/13\\\/jeffrey-aronson-when-i-use-a-word-apoptosis\\\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\\\/\\\/blogs.bmj.com\\\/bmj\\\/2017\\\/01\\\/13\\\/jeffrey-aronson-when-i-use-a-word-apoptosis\\\/#primaryimage\",\"url\":\"https:\\\/\\\/blogs.bmj.com\\\/bmj\\\/files\\\/2017\\\/01\\\/aronson_apoptosis2.png\",\"contentUrl\":\"https:\\\/\\\/blogs.bmj.com\\\/bmj\\\/files\\\/2017\\\/01\\\/aronson_apoptosis2.png\",\"width\":1916,\"height\":2032},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\\\/\\\/blogs.bmj.com\\\/bmj\\\/2017\\\/01\\\/13\\\/jeffrey-aronson-when-i-use-a-word-apoptosis\\\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\\\/\\\/blogs.bmj.com\\\/bmj\\\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Jeffrey Aronson: When I use a word . . . Apoptosis\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\\\/\\\/blogs.bmj.com\\\/bmj\\\/#website\",\"url\":\"https:\\\/\\\/blogs.bmj.com\\\/bmj\\\/\",\"name\":\"The BMJ\",\"description\":\"Helping doctors make better decisions.\",\"publisher\":{\"@id\":\"https:\\\/\\\/blogs.bmj.com\\\/bmj\\\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\\\/\\\/blogs.bmj.com\\\/bmj\\\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"},{\"@type\":\"Organization\",\"@id\":\"https:\\\/\\\/blogs.bmj.com\\\/bmj\\\/#organization\",\"name\":\"The BMJ\",\"url\":\"https:\\\/\\\/blogs.bmj.com\\\/bmj\\\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\\\/\\\/blogs.bmj.com\\\/bmj\\\/#\\\/schema\\\/logo\\\/image\\\/\",\"url\":\"https:\\\/\\\/blogs.bmj.com\\\/bmj\\\/files\\\/2018\\\/05\\\/The-BMJ-logo.jpg\",\"contentUrl\":\"https:\\\/\\\/blogs.bmj.com\\\/bmj\\\/files\\\/2018\\\/05\\\/The-BMJ-logo.jpg\",\"width\":852,\"height\":568,\"caption\":\"The BMJ\"},\"image\":{\"@id\":\"https:\\\/\\\/blogs.bmj.com\\\/bmj\\\/#\\\/schema\\\/logo\\\/image\\\/\"},\"sameAs\":[\"https:\\\/\\\/www.facebook.com\\\/bmjdotcom\\\/\",\"https:\\\/\\\/x.com\\\/bmj_latest\"]},{\"@type\":\"Person\",\"@id\":\"https:\\\/\\\/blogs.bmj.com\\\/bmj\\\/#\\\/schema\\\/person\\\/ba3da426ed20e8f1d933ca367d8216fe\",\"name\":\"BMJ\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/b4d8f39281bcae118348a1c027347b8e53b82d42520e774a8b50dd9a6ac6c01d?s=96&d=mm&r=g\",\"url\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/b4d8f39281bcae118348a1c027347b8e53b82d42520e774a8b50dd9a6ac6c01d?s=96&d=mm&r=g\",\"contentUrl\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/b4d8f39281bcae118348a1c027347b8e53b82d42520e774a8b50dd9a6ac6c01d?s=96&d=mm&r=g\",\"caption\":\"BMJ\"},\"sameAs\":[\"https:\\\/\\\/blogs.bmj.com\\\/\"],\"url\":\"https:\\\/\\\/blogs.bmj.com\\\/bmj\\\/author\\\/admin\\\/\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Jeffrey Aronson: When I use a word . . . Apoptosis - The BMJ","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/blogs.bmj.com\/bmj\/2017\/01\/13\/jeffrey-aronson-when-i-use-a-word-apoptosis\/","og_locale":"en_US","og_type":"article","og_title":"Jeffrey Aronson: When I use a word . . . Apoptosis - The BMJ","og_description":"In their landmark paper in the British Journal of Cancer 45 years ago, Kerr, Wyllie, and Currie reported a phenomenon that they described as \u201ccontrolled cell deletion\u201d. They proposed calling [...]More...","og_url":"https:\/\/blogs.bmj.com\/bmj\/2017\/01\/13\/jeffrey-aronson-when-i-use-a-word-apoptosis\/","og_site_name":"The BMJ","article_publisher":"https:\/\/www.facebook.com\/bmjdotcom\/","article_published_time":"2017-01-13T15:45:28+00:00","article_modified_time":"2017-01-16T13:56:47+00:00","og_image":[{"url":"https:\/\/blogs.bmj.com\/bmj\/files\/2017\/01\/aronson_apoptosis2.png","type":"","width":"","height":""}],"author":"BMJ","twitter_card":"summary_large_image","twitter_creator":"@bmj_latest","twitter_site":"@bmj_latest","twitter_misc":{"Written by":"BMJ","Est. reading time":"4 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/blogs.bmj.com\/bmj\/2017\/01\/13\/jeffrey-aronson-when-i-use-a-word-apoptosis\/#article","isPartOf":{"@id":"https:\/\/blogs.bmj.com\/bmj\/2017\/01\/13\/jeffrey-aronson-when-i-use-a-word-apoptosis\/"},"author":{"name":"BMJ","@id":"https:\/\/blogs.bmj.com\/bmj\/#\/schema\/person\/ba3da426ed20e8f1d933ca367d8216fe"},"headline":"Jeffrey Aronson: When I use a word . . . Apoptosis","datePublished":"2017-01-13T15:45:28+00:00","dateModified":"2017-01-16T13:56:47+00:00","mainEntityOfPage":{"@id":"https:\/\/blogs.bmj.com\/bmj\/2017\/01\/13\/jeffrey-aronson-when-i-use-a-word-apoptosis\/"},"wordCount":886,"commentCount":0,"publisher":{"@id":"https:\/\/blogs.bmj.com\/bmj\/#organization"},"image":{"@id":"https:\/\/blogs.bmj.com\/bmj\/2017\/01\/13\/jeffrey-aronson-when-i-use-a-word-apoptosis\/#primaryimage"},"thumbnailUrl":"https:\/\/blogs.bmj.com\/bmj\/files\/2017\/01\/aronson_apoptosis2.png","articleSection":["Jeff Aronson's Words"],"inLanguage":"en-US","potentialAction":[{"@type":"CommentAction","name":"Comment","target":["https:\/\/blogs.bmj.com\/bmj\/2017\/01\/13\/jeffrey-aronson-when-i-use-a-word-apoptosis\/#respond"]}]},{"@type":"WebPage","@id":"https:\/\/blogs.bmj.com\/bmj\/2017\/01\/13\/jeffrey-aronson-when-i-use-a-word-apoptosis\/","url":"https:\/\/blogs.bmj.com\/bmj\/2017\/01\/13\/jeffrey-aronson-when-i-use-a-word-apoptosis\/","name":"Jeffrey Aronson: When I use a word . . . Apoptosis - The BMJ","isPartOf":{"@id":"https:\/\/blogs.bmj.com\/bmj\/#website"},"primaryImageOfPage":{"@id":"https:\/\/blogs.bmj.com\/bmj\/2017\/01\/13\/jeffrey-aronson-when-i-use-a-word-apoptosis\/#primaryimage"},"image":{"@id":"https:\/\/blogs.bmj.com\/bmj\/2017\/01\/13\/jeffrey-aronson-when-i-use-a-word-apoptosis\/#primaryimage"},"thumbnailUrl":"https:\/\/blogs.bmj.com\/bmj\/files\/2017\/01\/aronson_apoptosis2.png","datePublished":"2017-01-13T15:45:28+00:00","dateModified":"2017-01-16T13:56:47+00:00","breadcrumb":{"@id":"https:\/\/blogs.bmj.com\/bmj\/2017\/01\/13\/jeffrey-aronson-when-i-use-a-word-apoptosis\/#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/blogs.bmj.com\/bmj\/2017\/01\/13\/jeffrey-aronson-when-i-use-a-word-apoptosis\/"]}]},{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/blogs.bmj.com\/bmj\/2017\/01\/13\/jeffrey-aronson-when-i-use-a-word-apoptosis\/#primaryimage","url":"https:\/\/blogs.bmj.com\/bmj\/files\/2017\/01\/aronson_apoptosis2.png","contentUrl":"https:\/\/blogs.bmj.com\/bmj\/files\/2017\/01\/aronson_apoptosis2.png","width":1916,"height":2032},{"@type":"BreadcrumbList","@id":"https:\/\/blogs.bmj.com\/bmj\/2017\/01\/13\/jeffrey-aronson-when-i-use-a-word-apoptosis\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/blogs.bmj.com\/bmj\/"},{"@type":"ListItem","position":2,"name":"Jeffrey Aronson: When I use a word . . . Apoptosis"}]},{"@type":"WebSite","@id":"https:\/\/blogs.bmj.com\/bmj\/#website","url":"https:\/\/blogs.bmj.com\/bmj\/","name":"The BMJ","description":"Helping doctors make better decisions.","publisher":{"@id":"https:\/\/blogs.bmj.com\/bmj\/#organization"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/blogs.bmj.com\/bmj\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"en-US"},{"@type":"Organization","@id":"https:\/\/blogs.bmj.com\/bmj\/#organization","name":"The BMJ","url":"https:\/\/blogs.bmj.com\/bmj\/","logo":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/blogs.bmj.com\/bmj\/#\/schema\/logo\/image\/","url":"https:\/\/blogs.bmj.com\/bmj\/files\/2018\/05\/The-BMJ-logo.jpg","contentUrl":"https:\/\/blogs.bmj.com\/bmj\/files\/2018\/05\/The-BMJ-logo.jpg","width":852,"height":568,"caption":"The BMJ"},"image":{"@id":"https:\/\/blogs.bmj.com\/bmj\/#\/schema\/logo\/image\/"},"sameAs":["https:\/\/www.facebook.com\/bmjdotcom\/","https:\/\/x.com\/bmj_latest"]},{"@type":"Person","@id":"https:\/\/blogs.bmj.com\/bmj\/#\/schema\/person\/ba3da426ed20e8f1d933ca367d8216fe","name":"BMJ","image":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/secure.gravatar.com\/avatar\/b4d8f39281bcae118348a1c027347b8e53b82d42520e774a8b50dd9a6ac6c01d?s=96&d=mm&r=g","url":"https:\/\/secure.gravatar.com\/avatar\/b4d8f39281bcae118348a1c027347b8e53b82d42520e774a8b50dd9a6ac6c01d?s=96&d=mm&r=g","contentUrl":"https:\/\/secure.gravatar.com\/avatar\/b4d8f39281bcae118348a1c027347b8e53b82d42520e774a8b50dd9a6ac6c01d?s=96&d=mm&r=g","caption":"BMJ"},"sameAs":["https:\/\/blogs.bmj.com\/"],"url":"https:\/\/blogs.bmj.com\/bmj\/author\/admin\/"}]}},"_links":{"self":[{"href":"https:\/\/blogs.bmj.com\/bmj\/wp-json\/wp\/v2\/posts\/38162","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/blogs.bmj.com\/bmj\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/blogs.bmj.com\/bmj\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/blogs.bmj.com\/bmj\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/blogs.bmj.com\/bmj\/wp-json\/wp\/v2\/comments?post=38162"}],"version-history":[{"count":0,"href":"https:\/\/blogs.bmj.com\/bmj\/wp-json\/wp\/v2\/posts\/38162\/revisions"}],"wp:attachment":[{"href":"https:\/\/blogs.bmj.com\/bmj\/wp-json\/wp\/v2\/media?parent=38162"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/blogs.bmj.com\/bmj\/wp-json\/wp\/v2\/categories?post=38162"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/blogs.bmj.com\/bmj\/wp-json\/wp\/v2\/tags?post=38162"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}