{"id":34668,"date":"2015-07-09T11:07:04","date_gmt":"2015-07-09T10:07:04","guid":{"rendered":"https:\/\/blogs.bmj.com\/bmj\/?p=34668"},"modified":"2015-07-09T11:07:41","modified_gmt":"2015-07-09T10:07:41","slug":"the-bmj-today-the-safety-of-ssris-during-pregnancy","status":"publish","type":"post","link":"https:\/\/blogs.bmj.com\/bmj\/2015\/07\/09\/the-bmj-today-the-safety-of-ssris-during-pregnancy\/","title":{"rendered":"The BMJ Today: The safety of SSRIs during pregnancy, controversial trade deals, and bow legs and knock knees"},"content":{"rendered":"<p><a href=\"https:\/\/blogs.bmj.com\/bmj\/files\/2015\/07\/pregnancy_pills1.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"alignleft size-thumbnail wp-image-34672\" src=\"https:\/\/blogs.bmj.com\/bmj\/files\/2015\/07\/pregnancy_pills1-150x150.jpg\" alt=\"pregnancy_pills\" width=\"150\" height=\"150\" \/><\/a><strong>\u2022\u00a0Specific SSRIs and birth defects<\/strong><br \/>\nThe association between maternal use of antidepressants, especially selective serotonin reuptake inhibitors (SSRIs), during pregnancy and birth defects has been the topic of much discussion in recent years. Recent meta-analyses and systematic reviews have reached conflicting conclusions, so\u00a0<a href=\"http:\/\/www.bmj.com\/content\/351\/bmj.h3190\">J Reefhuis and colleagues carried out a\u00a0bayesian analysis<\/a> to interpret new data in the context of previous reports and to try to provide some clarity on this uncertainty.<\/p>\n<p>The authors data provide reassuring evidence for some SSRIs but suggest that some birth defects occur 2-3.5 times more frequently among the infants of women treated with paroxetine or fluoxetine early in pregnancy. <a href=\"http:\/\/www.bmj.com\/content\/351\/bmj.h3190\">Read their findings to help\u00a0guide you in the safest treatment options during early pregnancy<\/a>.<!--more--><\/p>\n<p><a href=\"https:\/\/blogs.bmj.com\/bmj\/files\/2015\/07\/obama_jan2015.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"alignleft size-thumbnail wp-image-34673\" src=\"https:\/\/blogs.bmj.com\/bmj\/files\/2015\/07\/obama_jan2015-150x150.jpg\" alt=\"obama_jan2015\" width=\"150\" height=\"150\" \/><\/a><strong>\u2022 New Pacific trade deal\u2014good for pharma, bad for public health?<\/strong><\/p>\n<p>US president Barack Obama has hailed\u00a0the vast trade deal known as the Trans-Pacific Partnership (TPP) as \u201cthe most positive trade deal in history.\u201d Not everyone shares his enthusiasm though, with its detractors denouncing the TPP\u00a0as a\u00a0shameful sell out, which favours corporations over individuals and poses a grave threat to public health. Journalist\u00a0<a href=\"http:\/\/www.bmj.com\/content\/351\/bmj.h3649\">Jonathan Gornall looks at why this planned deal between\u00a012 Asia-Pacific Rim countries is so divisive<\/a>, covering\u00a0what the TPP is, why health groups are worried\u00a0about it, and what&#8217;s likely to happen next.<\/p>\n<p>If you want still more reading about controversial trade deals, you can read some comment articles about\u00a0the Transatlantic Trade and Investment Partnership (TTIP), between the European Union and United States. There&#8217;s this editorial on <a href=\"http:\/\/www.bmj.com\/content\/349\/bmj.g6552\">the TTIP\u00a0and UK healthcare<\/a>, and\u00a0this observations piece, <a href=\"http:\/\/www.bmj.com\/content\/350\/bmj.h2179\">exploring if the NHS is safe from international trade agreements<\/a>\u2014as well as a new editorial on <a href=\"http:\/\/www.bmj.com\/content\/351\/bmj.h3652\">rethinking governance for trade and health<\/a>.<\/p>\n<p><a href=\"https:\/\/blogs.bmj.com\/bmj\/files\/2015\/07\/cr_lowerlimb.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"alignleft wp-image-34674 \" src=\"https:\/\/blogs.bmj.com\/bmj\/files\/2015\/07\/cr_lowerlimb-300x194.jpg\" alt=\"cr_lowerlimb\" width=\"223\" height=\"144\" srcset=\"https:\/\/blogs.bmj.com\/bmj\/files\/2015\/07\/cr_lowerlimb-300x194.jpg 300w, https:\/\/blogs.bmj.com\/bmj\/files\/2015\/07\/cr_lowerlimb.jpg 540w\" sizes=\"auto, (max-width: 223px) 100vw, 223px\" \/><\/a><strong>\u2022\u00a0Normal lower limb variants in children<\/strong><\/p>\n<p>Bow legs, knock knees, flat feet, intoeing, and out-toeing gaits in children are common conditions, but often cause undue parental anxiety, prompting frequent visits to general practice. <a href=\"http:\/\/www.bmj.com\/content\/351\/bmj.h3394\">This clinical review assists general clinicians<\/a> in recognising normal physiological variants in the lower limbs of children and in identifying abnormal features that require specialist attention.<\/p>\n<p>The <a href=\"http:\/\/www.bmj.com\/content\/351\/bmj.h3394\">review also includes<\/a> numerous figures and a video demonstrating normal variants and abnormal conditions according to age.<\/p>\n<p><em><strong>Kelly Brendel<\/strong> is assistant web editor at <\/em>The BMJ<em>.\u00a0<\/em><\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u2022\u00a0Specific SSRIs and birth defects The association between maternal use of antidepressants, especially selective serotonin reuptake inhibitors (SSRIs), during pregnancy and birth defects has been the topic of much discussion [&#8230;]<\/p>\n<p><a class=\"btn btn-secondary understrap-read-more-link\" href=\"https:\/\/blogs.bmj.com\/bmj\/2015\/07\/09\/the-bmj-today-the-safety-of-ssris-during-pregnancy\/\">More&#8230;<\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[5750],"tags":[],"class_list":["post-34668","post","type-post","status-publish","format-standard","hentry","category-the-bmj-today"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.5 - 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