{"id":31917,"date":"2014-07-09T09:25:31","date_gmt":"2014-07-09T08:25:31","guid":{"rendered":"https:\/\/blogs.bmj.com\/bmj\/?p=31917"},"modified":"2014-07-09T09:25:31","modified_gmt":"2014-07-09T08:25:31","slug":"sean-roche-resistance-what-society-needs-to-learn-from-the-microbes","status":"publish","type":"post","link":"https:\/\/blogs.bmj.com\/bmj\/2014\/07\/09\/sean-roche-resistance-what-society-needs-to-learn-from-the-microbes\/","title":{"rendered":"Sean Roche: Resistance\u2014what society needs to learn from the microbes"},"content":{"rendered":"<p><a href=\"https:\/\/blogs.bmj.com\/bmj\/2013\/06\/17\/sean-roche-wake-up-and-smell-the-coffee-or-the-essential-non-being-of-the-francis-report\/sean_roche\/\" rel=\"attachment wp-att-27171\"><img loading=\"lazy\" decoding=\"async\" class=\"alignleft size-full wp-image-27171\" src=\"https:\/\/blogs.bmj.com\/bmj\/files\/2013\/06\/sean_roche.jpg\" alt=\"sean_roche\" width=\"160\" height=\"120\" \/><\/a>The first week in July saw <a href=\"http:\/\/www.bmj.com\/content\/349\/bmj.g4472\">extensive media coverage<\/a> of the looming specter of microbial antibiotic resistance. The basic problem: Big Pharma isn\u2019t developing new antibiotics. We look on, seemingly helpless, in the face of ever evolving strains of dangerous, resistant \u201csuperbugs.\u201d<\/p>\n<p>The logic of this scenario is familiar, and mirrors perfectly our apparent helplessness in the wake of the slow motion unfolding of the planet\u2019s ecological collapse. We know that fossil fuels are toxic for the environment, and yet Big Oil continues its voracious extraction, unabated, as the climate warms year on year.<!--more--><\/p>\n<p>What is the underlying pathology here? Put simply, we live in a world in which the profit motive overrides the human motive. Of course, free market converts see no problem with this. A central doctrine of free market fundamentalism is belief in the market\u2019s benevolent \u201cinvisible hand,\u201d a hand that opens generously and gives in the face of human needs. This miraculous \u201cinvisible hand,\u201d devotees claim, will ensure that profit and human interests are aligned. And yet, as experience teaches so often, this hand delivers a bloody punch on the nose instead.<\/p>\n<p>It\u2019s sad to say, but Big Pharma seems much more interested in the health of shareholder portfolios than the health of the global citizenry. If the human motive (affordable drugs for poor countries, new antibiotics, etc.) does not align with the profit motive, then that\u2019s just too bad.<\/p>\n<p>New antibiotics are simply not profitable. They will be costly to develop, and then held in special clinical reserve to use only when other agents fail. By comparison, they just don\u2019t compete with cholesterol lowering drugs. If there\u2019s one thing the world (and shareholders) can do with, it\u2019s yet another statin. This absurd situation belies another myth: that of the endless beneficial progress of capitalism. On the contrary, the profit motive can keep innovation on a tight leash\u2014progress can\u00a0be stifled as often as it is set free.<\/p>\n<p>The list of Big Pharma\u2019s sins is well known: disease mongering, overpricing, bribery, falsification and concealment of data, and pulling research from unprofitable areas such as neuroscience. And so on. Alas, like a toxin, the profit motive spreads and pervades all the tissues of the social body. We need to learn the Darwinian lessons from our microbial ancestors. We need to resist, evolve, and adapt.<\/p>\n<p>In the face of the evolving crisis that is antibiotic resistance, the logical adaptation is to wrest control of the research agenda from Big Pharma\u2019s executive boardroom, and hand it back to a state whose interest is more invested in the health of its citizens. And yes, perhaps ultimately the pharmaceutical industry should be in public, not private hands. The human motive must triumph over the profit motive. Resistance is the key.<\/p>\n<p><em><strong>Sean Roche<\/strong>\u00a0is a consultant psychiatrist in North London, and was a visiting research fellow in philosophy at King\u2019s College London 2012-14. After completing his philosophy PhD in 2011 he has maintained a research interest in philosophical and political issues that are relevant to both psychiatry and medicine.<\/em><\/p>\n<p>I declare that I have read and understood the BMJ policy on declaration of interests and I have no relevant interests to declare.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>The first week in July saw extensive media coverage of the looming specter of microbial antibiotic resistance. The basic problem: Big Pharma isn\u2019t developing new antibiotics. We look on, seemingly [&#8230;]<\/p>\n<p><a class=\"btn btn-secondary understrap-read-more-link\" href=\"https:\/\/blogs.bmj.com\/bmj\/2014\/07\/09\/sean-roche-resistance-what-society-needs-to-learn-from-the-microbes\/\">More&#8230;<\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[223],"tags":[],"class_list":["post-31917","post","type-post","status-publish","format-standard","hentry","category-guest-bloggers"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.6 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Sean Roche: Resistance\u2014what society needs to learn from the microbes - The BMJ<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/blogs.bmj.com\/bmj\/2014\/07\/09\/sean-roche-resistance-what-society-needs-to-learn-from-the-microbes\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Sean Roche: Resistance\u2014what society needs to learn from the microbes - The BMJ\" \/>\n<meta property=\"og:description\" content=\"The first week in July saw extensive media coverage of the looming specter of microbial antibiotic resistance. 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