{"id":1978,"date":"2011-10-18T04:42:35","date_gmt":"2011-10-18T03:42:35","guid":{"rendered":"https:\/\/blogs.bmj.com\/bjsm\/?p=1978"},"modified":"2011-10-18T20:50:19","modified_gmt":"2011-10-18T19:50:19","slug":"no-magical-therapeutic-benefit-of-prp-in-achilles-tendinopathy-jama-paper-follow-up-and-bjsm-podcast","status":"publish","type":"post","link":"https:\/\/blogs.bmj.com\/bjsm\/2011\/10\/18\/no-magical-therapeutic-benefit-of-prp-in-achilles-tendinopathy-jama-paper-follow-up-and-bjsm-podcast\/","title":{"rendered":"No magical therapeutic benefit of PRP in Achilles tendinopathy &#8212; JAMA paper follow-up and BJSM podcast"},"content":{"rendered":"<p style=\"text-align: center\"><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-2001 aligncenter\" title=\"untitled\" src=\"https:\/\/blogs.bmj.com\/bjsm\/files\/2011\/10\/PRP-Final-BJSM-cover1.jpg\" alt=\"\" width=\"230\" height=\"309\" \/><\/p>\n<p style=\"text-align: left\">My sense is that the popularity of platelet-rich plasma (PRP) is increasing independent of research in this field. BJSM has covered this with front cover attention:<\/p>\n<ul>\n<li><strong><a href=\"http:\/\/bjsm.bmj.com\/content\/44\/9.toc\" target=\"_blank\">Platelet-rich plasma: Debate. <\/a><\/strong><a href=\"http:\/\/bjsm.bmj.com\/content\/44\/9.toc\" target=\"_blank\">Jul 2010, (44)9<\/a><\/li>\n<li><strong><a href=\"http:\/\/bjsm.bmj.com\/content\/44\/15.toc\" target=\"_blank\">IOC consensus paper on the use of platelet-rich plasma in sports medicine.<\/a><span style=\"font-weight: normal\"><a href=\"http:\/\/bjsm.bmj.com\/content\/44\/15.toc\" target=\"_blank\"> Dec 2010, (44)15<\/a><\/span><\/strong><\/li>\n<\/ul>\n<p>Of most interest to blog readers will be the <a href=\"http:\/\/podcasts.bmj.com\/bjsm\/category\/robert-jan-de-vos\/\" target=\"_blank\">Podcast on PRP with\u00a0Robert Jan de Vos and Adam Weir<\/a>. These authors have arguably the highest quality study testing PRP to date.  We congratulate the Dutch researchers on their quality study design and comprehensive investigations.<\/p>\n<p><strong>Conclusions?<\/strong><\/p>\n<p><strong> <\/strong> &#8211; No clinical benefit in 6 months:<\/p>\n<ul>\n<li><a href=\"http:\/\/jama.ama-assn.org\/content\/303\/2\/144.abstract\" target=\"_blank\">de Vos, R, Weir, A et al. 2010. <\/a><strong><a href=\"http:\/\/jama.ama-assn.org\/content\/303\/2\/144.abstract\" target=\"_blank\">Platelet-Rich Plasma Injection for Chronic Achilles Tendinopathy. <\/a><\/strong><a href=\"http:\/\/jama.ama-assn.org\/content\/303\/2\/144.abstract\" target=\"_blank\">JAMA, 303(2)<\/a><\/li>\n<\/ul>\n<p>&#8211;\u00a0\u00a0No ultrasound evidence of benefit:<\/p>\n<ul>\n<li><a href=\"http:\/\/bjsm.bmj.com\/content\/45\/5\/387.full?sid=55e2a47a-e1db-4787-93ec-779603f0fd9e\" target=\"_blank\">de Vos, R, Weir, A et al. 2010. <\/a><strong><a href=\"http:\/\/bjsm.bmj.com\/content\/45\/5\/387.full?sid=55e2a47a-e1db-4787-93ec-779603f0fd9e\" target=\"_blank\">No effects of PRP on ultrasonographic tendon structure and neovascularisation in chronic midportion Achilles tendinopathy. <\/a><\/strong><a href=\"http:\/\/bjsm.bmj.com\/content\/45\/5\/387.full?sid=55e2a47a-e1db-4787-93ec-779603f0fd9e\" target=\"_blank\">BJSM, Online first November, 2010<\/a><\/li>\n<\/ul>\n<p>&#8211; and now no benefit at 12 months:<\/p>\n<ul>\n<li><a href=\"http:\/\/ajs.sagepub.com\/content\/early\/2011\/05\/20\/0363546511404877\" target=\"_blank\"> de Jonge, S, de Vos, R., Weir, A et al. 2011. <\/a><strong><a href=\"http:\/\/ajs.sagepub.com\/content\/early\/2011\/05\/20\/0363546511404877\" target=\"_blank\">One-Year Follow-up of Platelet-Rich Plasma Treatment in Chronic Achilles Tendinopathy: A Double-Blind Randomized Placebo-Controlled Trial. <\/a><cite><abbr title=\"The American Journal of Sports Medicine\"><span style=\"font-style: normal\"><span style=\"font-weight: normal\"><a href=\"http:\/\/ajs.sagepub.com\/content\/early\/2011\/05\/20\/0363546511404877\" target=\"_blank\">AJSM<\/a>. <\/span><\/span><\/abbr><span style=\"font-style: normal\"><span style=\"font-weight: normal\"><a href=\"http:\/\/ajs.sagepub.com\/content\/early\/2011\/05\/20\/0363546511404877\" target=\"_blank\">August \u00a039.<\/a><\/span><\/span><\/cite><\/strong><\/li>\n<\/ul>\n<p>No benefit at 12 months is not a surprise given previous findings. The proposed mechanism for PRP therapy is accelerated early healing. Nevertheless, these data are important as some evangelical PRP providers may be tempted to discount the 6-month results and argue for a &#8216;delayed benefit&#8217;. This is not the last word on PRP and BJSM Associate Editor Kim Harmon (see:\u00a0<strong><a href=\"http:\/\/bjsm.bmj.com\/content\/44\/16\/1135.full?sid=0f982707-136a-4a5a-a9c4-dd8437fb269a\" target=\"_blank\">Musculoskeletal ultrasound: taking sports medicine to the next level<\/a><\/strong>)\u00a0has pointed out reasons for this series of Dutch studies having &#8216;no effect&#8217;.  BJSM is one of the leading venues for rational debate on PRP and we look forward to adding to your knowledge about the clinical utility of this &#8216;hot&#8217; therapy that is gaining clinical popularity. Time for a quality randomized trial of PRP versus the Alfredson program for Achilles tendinopathy?<!--TrendMD v2.4.8--><\/p>\n","protected":false},"excerpt":{"rendered":"<p>My sense is that the popularity of platelet-rich plasma (PRP) is increasing independent of research in this field. BJSM has covered this with front cover attention: Platelet-rich plasma: Debate. Jul 2010, (44)9 IOC consensus paper on the use of platelet-rich plasma in sports medicine. Dec 2010, (44)15 Of most interest to blog readers will be [&#8230;]<\/p>\n<p><a class=\"btn btn-secondary understrap-read-more-link\" href=\"https:\/\/blogs.bmj.com\/bjsm\/2011\/10\/18\/no-magical-therapeutic-benefit-of-prp-in-achilles-tendinopathy-jama-paper-follow-up-and-bjsm-podcast\/\">Read More&#8230;<\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1,202,317],"tags":[1859],"class_list":["post-1978","post","type-post","status-publish","format-standard","hentry","category-uncategorized","category-podcast","category-research","tag-platelet-rich-plasma"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.6 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>No magical therapeutic benefit of PRP in Achilles tendinopathy - JAMA paper follow-up and BJSM podcast - BJSM blog - social media&#039;s leading SEM voice<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/blogs.bmj.com\/bjsm\/2011\/10\/18\/no-magical-therapeutic-benefit-of-prp-in-achilles-tendinopathy-jama-paper-follow-up-and-bjsm-podcast\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"No magical therapeutic benefit of PRP in Achilles tendinopathy - JAMA paper follow-up and BJSM podcast - BJSM blog - social media&#039;s leading SEM voice\" \/>\n<meta property=\"og:description\" content=\"My sense is that the popularity of platelet-rich plasma (PRP) is increasing independent of research in this field. BJSM has covered this with front cover attention: Platelet-rich plasma: Debate. Jul 2010, (44)9 IOC consensus paper on the use of platelet-rich plasma in sports medicine. 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BJSM has covered this with front cover attention: Platelet-rich plasma: Debate. Jul 2010, (44)9 IOC consensus paper on the use of platelet-rich plasma in sports medicine. 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