{"id":122,"date":"2009-10-07T21:50:34","date_gmt":"2009-10-07T20:50:34","guid":{"rendered":"https:\/\/blogs.bmj.com\/bjsm\/?p=122"},"modified":"2009-10-07T21:50:34","modified_gmt":"2009-10-07T20:50:34","slug":"e-letter-prophylactic-use-of-nsaids-in-endurance-runners","status":"publish","type":"post","link":"https:\/\/blogs.bmj.com\/bjsm\/2009\/10\/07\/e-letter-prophylactic-use-of-nsaids-in-endurance-runners\/","title":{"rendered":"E-letter: Prophylactic use of NSAIDs in endurance runners"},"content":{"rendered":"

Click <\/strong><\/em>here<\/strong><\/em><\/a> to read the original article.<\/strong><\/em><\/p>\n

\n

My concern with the prophylactic use of NSAIDs occurs in endurance\u00a0athletes. My anecdotal experience is that endurance runners attempting\u00a0distances categorised as ultra races (ie longer than a marathon) may\u00a0regularly take NSAIDs during an event in a misguided attempt to delay\u00a0muscle fatigue. I have even seen NSAIDs being referred to as “Vitamin\u00a0I”\u00a0in some running literature.<\/p>\n

Acute renal failure with NSAID therapy is mediated hemodynamically\u00a0as a result of decreased renal perfusion after inhibition of\u00a0prostacyclin synthesis. Decreased renal perfusion in ultra distance\u00a0events can be caused by dehydration. Factor into the equation the muscle\u00a0breakdown that occurs in these events and possible rhabdomyolysis.<\/p>\n

This triple insult to the kidneys can lead to renal failure and\u00a0dialysis, if not death. I suspect that many ultra endurance athletes,\u00a0whether this be running or triathlon, are unaware of the possibility of\u00a0renal failure that may occur when prophylactically taking NSAIDs during\u00a0an event.<\/p>\n

Stephen H. Boyce
\nConsultant Emergency Medicine
\nWishaw General Hospital, North Lanarkshire, Scotland<\/p>\n","protected":false},"excerpt":{"rendered":"

Click here to read the original article. My concern with the prophylactic use of NSAIDs occurs in endurance\u00a0athletes. My anecdotal experience is that endurance runners attempting\u00a0distances categorised as ultra races (ie longer than a marathon) may\u00a0regularly take NSAIDs during an event in a misguided attempt to delay\u00a0muscle fatigue. I have even seen NSAIDs being referred […]<\/p>\n

Read More…<\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":["post-122","post","type-post","status-publish","format-standard","hentry","category-uncategorized"],"yoast_head":"\nE-letter: Prophylactic use of NSAIDs in endurance runners - BJSM blog - social media's leading SEM voice<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/blogs.bmj.com\/bjsm\/2009\/10\/07\/e-letter-prophylactic-use-of-nsaids-in-endurance-runners\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"E-letter: Prophylactic use of NSAIDs in endurance runners - BJSM blog - social media's leading SEM voice\" \/>\n<meta property=\"og:description\" content=\"Click here to read the original article. My concern with the prophylactic use of NSAIDs occurs in endurance\u00a0athletes. My anecdotal experience is that endurance runners attempting\u00a0distances categorised as ultra races (ie longer than a marathon) may\u00a0regularly take NSAIDs during an event in a misguided attempt to delay\u00a0muscle fatigue. 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