{"id":11846,"date":"2026-01-23T06:00:53","date_gmt":"2026-01-23T05:00:53","guid":{"rendered":"https:\/\/blogs.bmj.com\/bjsm\/?p=11846"},"modified":"2026-01-22T10:23:28","modified_gmt":"2026-01-22T09:23:28","slug":"cryotherapy-in-the-postoperative-care-of-musculoskeletal-disorders","status":"publish","type":"post","link":"https:\/\/blogs.bmj.com\/bjsm\/2026\/01\/23\/cryotherapy-in-the-postoperative-care-of-musculoskeletal-disorders\/","title":{"rendered":"Cryotherapy in the postoperative care of musculoskeletal disorders"},"content":{"rendered":"<p><b>Key words: <\/b><span style=\"font-weight: 400\">Physical Therapy Modalities; Surgical Procedures; Systematic review.<\/span><\/p>\n<p><b>Why is this study important?<\/b><\/p>\n<p><span style=\"font-weight: 400\">Cryotherapy, the use of ice or cold for therapeutic purposes, is a widely used intervention in the rehabilitation and postoperative care of musculoskeletal injuries. Its popularity likely stems from being low-cost, easy to apply, and accessible for patients. Many recommendations in clinical practice rely on theoretical physiological mechanisms, and some guidelines still endorse cryotherapy on this basis (1, 2). However, the evidence regarding the effectiveness of cryotherapy on clinical outcomes is uncertain (3, 4). To better inform clinicians and patients, it is important to investigate the effectiveness of cryotherapy in postoperative musculoskeletal care, thereby understanding its clinical relevance.\u00a0<\/span><\/p>\n<p><b>How did the study go about this?<\/b><\/p>\n<p><span style=\"font-weight: 400\">We conducted a systematic review of Randomised Controlled Trials (RCTs). Searches were conducted across four scientific databases: MEDLINE, COCHRANE, EMBASE, and PEDro. We included trials involving individuals recovering from musculoskeletal surgeries such as ligament reconstructions, arthroplasties, and arthroscopies, among others. In each study, the experimental groups received cryotherapy, while the comparison groups received identical care without the cold component.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400\">We focused on clinical outcomes, including pain intensity, range of motion, swelling, and function, measured across four time points: immediate (up to 3 days after allocation), short-term (3 to 14 days), medium-term (14 days to 12 weeks), and long-term (&gt;12 weeks). Using meta-analysis, we pooled effect sizes and evaluated whether these differences reach the level of clinical relevance based on the Minimum Clinically Important Difference (MCID).<\/span><\/p>\n<p><b>What did the study find?<\/b><\/p>\n<p><span style=\"font-weight: 400\">We included 28 RCTs. The results are summarised below, expressed as Mean Difference (MD) or Standardised Mean Difference (SMD), along with their respective 95% confidence intervals.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400\">Pain intensity (0-10 scale, 0 meaning no pain and 10 worst pain)<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Immediate term: MD \u22120.77 (\u22121.23 to \u22120.31)<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Short term: MD \u22120.84 (\u22121.17 to \u22120.51)<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Medium term: MD \u22120.41 (\u22120.65 to \u22120.17)<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400\">These differences were statistically significant but did not reach the MCID of 2 points. There was no statistically significant difference in the long term.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400\">Function (0-100 scale, higher values meaning better function)\u00a0<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Short-term: MD 3.45 (0.69 to 6.20)<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400\">This difference was statistically significant but below the MCID of 11 points. There were no statistically significant differences in the medium- and long-term outcomes.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400\">Range of motion<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Immediate term: SMD 0.37 (0.09 to 0.66)<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Short term: SMD 0.51 (0.25 to 0.77)<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Medium term: SMD 0.61 (0.04 to 1.18)<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400\">A sensitivity analysis including only studies evaluating knee flexion range of motion in degrees demonstrated the following results:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Immediate term: MD 10.43\u00b0 (0.31 to 20.55)<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Short-term: MD 0.51\u00b0 (0.25 to 0.77)<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Medium-term: MD 4.82\u00b0 (1.30 to 8.34)<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400\">Swelling<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Short term: SMD \u22120.35 (\u22120.64 to \u22120.05)\u00a0<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400\">No statistically significant difference was found in either the immediate or medium-term. A sensitivity analysis including only studies evaluating limb circumference in centimetres showed reductions of:\u00a0<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Immediate term: MD \u22120.69 cm (\u22120.99 to \u22120.39)<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Short-term: MD \u22120.70 cm (\u22120.98 to \u22120.42)<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Medium-term: MD \u22120.73 cm (\u22121.26 to 0.20)<\/span><\/li>\n<\/ul>\n<p><b>What are the key take-home points?<\/b><\/p>\n<p><span style=\"font-weight: 400\">Cryotherapy demonstrated statistically significant differences in pain intensity and range of motion from the immediate to the medium term. No statistically significant difference was found in any of the long-term outcomes. These effects may be too small to be considered clinically relevant, as the differences did not reach the MCIDs. Therefore, cryotherapy may not be an indispensable intervention in the postoperative management of musculoskeletal disorders due to its minor effect size and no impact in the long term. Its use must be carefully considered in terms of time, cost, patient preference, and the availability of alternative interventions with stronger evidence of effectiveness.\u00a0<\/span><\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"alignnone wp-image-11847\" src=\"https:\/\/blogs.bmj.com\/bjsm\/files\/2026\/01\/BJSM_last-version-257x300.jpg\" alt=\"\" width=\"646\" height=\"753\" srcset=\"https:\/\/blogs.bmj.com\/bjsm\/files\/2026\/01\/BJSM_last-version-257x300.jpg 257w, https:\/\/blogs.bmj.com\/bjsm\/files\/2026\/01\/BJSM_last-version-768x896.jpg 768w, https:\/\/blogs.bmj.com\/bjsm\/files\/2026\/01\/BJSM_last-version-640x747.jpg 640w, https:\/\/blogs.bmj.com\/bjsm\/files\/2026\/01\/BJSM_last-version.jpg 1134w\" sizes=\"auto, (max-width: 646px) 100vw, 646px\" \/><\/p>\n<p><b>References<\/b><\/p>\n<p><span style=\"font-weight: 400\">(1) Racinais S, Dablainville V, Rousse Y, <\/span><i><span style=\"font-weight: 400\">et\u00a0al<\/span><\/i><span style=\"font-weight: 400\">. Cryotherapy for treating soft tissue injuries in sport medicine: a critical review. <\/span><i><span style=\"font-weight: 400\">Br J Sports Med<\/span><\/i><span style=\"font-weight: 400\"> 2024;58:1215\u201323.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400\">(2) Vuurberg G, Hoorntje A, Wink LM, <\/span><i><span style=\"font-weight: 400\">et\u00a0al<\/span><\/i><span style=\"font-weight: 400\">. Diagnosis, treatment and prevention of ankle sprains: update of an evidence-based clinical guideline. <\/span><i><span style=\"font-weight: 400\">Br J Sports Med<\/span><\/i><span style=\"font-weight: 400\"> 2018;52:956.<\/span><\/p>\n<p><span style=\"font-weight: 400\">(3) Miranda JP, Silva WT, Silva HJ, <\/span><i><span style=\"font-weight: 400\">et\u00a0al<\/span><\/i><span style=\"font-weight: 400\">. Effectiveness of cryotherapy on pain intensity, swelling, range of motion, function and recurrence in acute ankle sprain: A systematic review of randomized controlled trials. <\/span><i><span style=\"font-weight: 400\">Phys Ther Sport<\/span><\/i><span style=\"font-weight: 400\"> 2021;49:243\u20139.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400\">(4) Aggarwal A, Adie S, Harris IA, <\/span><i><span style=\"font-weight: 400\">et\u00a0al<\/span><\/i><span style=\"font-weight: 400\">. Cryotherapy following total knee replacement. <\/span><i><span style=\"font-weight: 400\">Cochrane Database Syst Rev<\/span><\/i><span style=\"font-weight: 400\"> 2023;9:CD007911.\u00a0<\/span><\/p>\n<p><b>Author and affiliations<\/b><\/p>\n<p><span style=\"font-weight: 400\">J\u00falio Pascoal de Miranda\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400\">Postgraduate Program in Rehabilitation and Functional Performance, Universidade Federal dos Vales do Jequitinhonha e Mucuri, Diamantina, Brazil. <\/span><a href=\"http:\/\/orcid.org\/0000-0002-7125-8813\"><span style=\"font-weight: 400\">http:\/\/orcid.org\/0000-0002-7125-8813<\/span><\/a><\/p>\n<p><span style=\"font-weight: 400\">Rafaela Calixto Cortez Figueiredo\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400\">Postgraduate Program in Rehabilitation and Functional Performance, Universidade Federal dos Vales do Jequitinhonha e Mucuri, Diamantina, Brazil\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400\">Bruno Tirotti Saragiotto\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400\">Discipline of Physiotherapy, University of Technology Sydney, Sydney, New South Wales, Australia. <\/span><a href=\"http:\/\/orcid.org\/0000-0003-4409-8057\"><span style=\"font-weight: 400\">http:\/\/orcid.org\/0000-0003-4409-8057<\/span><\/a><\/p>\n<p><span style=\"font-weight: 400\">Vin\u00edcius Cunha Oliveira\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400\">Postgraduate Program in Rehabilitation and Functional Performance, Universidade Federal dos Vales do Jequitinhonha e Mucuri, Diamantina, Brazil. <\/span><a href=\"http:\/\/orcid.org\/0000-0002-8658-3774\"><span style=\"font-weight: 400\">http:\/\/orcid.org\/0000-0002-8658-3774<\/span><\/a><!--TrendMD v2.4.8--><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Key words: Physical Therapy Modalities; Surgical Procedures; Systematic review. Why is this study important? Cryotherapy, the use of ice or cold for therapeutic purposes, is a widely used intervention in the rehabilitation and postoperative care of musculoskeletal injuries. Its popularity likely stems from being low-cost, easy to apply, and accessible for patients. Many recommendations in [&#8230;]<\/p>\n<p><a class=\"btn btn-secondary understrap-read-more-link\" href=\"https:\/\/blogs.bmj.com\/bjsm\/2026\/01\/23\/cryotherapy-in-the-postoperative-care-of-musculoskeletal-disorders\/\">Read More&#8230;<\/a><\/p>\n","protected":false},"author":463,"featured_media":11848,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[3002,16068,3014],"class_list":["post-11846","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-uncategorized","tag-cryotherapy","tag-featured","tag-systematic-review"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.6 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Cryotherapy in the postoperative care of musculoskeletal disorders - BJSM blog - social media&#039;s leading SEM voice<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/blogs.bmj.com\/bjsm\/?p=11846\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Cryotherapy in the postoperative care of musculoskeletal disorders - BJSM blog - social media&#039;s leading SEM voice\" \/>\n<meta property=\"og:description\" content=\"Key words: Physical Therapy Modalities; Surgical Procedures; Systematic review. Why is this study important? Cryotherapy, the use of ice or cold for therapeutic purposes, is a widely used intervention in the rehabilitation and postoperative care of musculoskeletal injuries. Its popularity likely stems from being low-cost, easy to apply, and accessible for patients. 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